Data Sheet 3_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf حسب Lu Ding (475637)

"…Increased tyrosine, glutamine, phenylalanine, sphingomyelin, glutamate, lactate and glucose, and decreased LysoPC (18:2), histidine, and methionine levels were linked to IS onset. …"

Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table_2_Combinatorial protection of cochlear hair cells: not too little but not too much.docx حسب Arwa Kurabi (344167)

"…The optimal combination of four compounds consisted of an anti-oxidant, an apoptosis inhibitor, an autophagy inhibitor and a protective growth factor. Increasing the number of factors to five or six resulted in decreased protection.…"

Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table 1_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Table_4_Combinatorial protection of cochlear hair cells: not too little but not too much.docx حسب Arwa Kurabi (344167)

"…The optimal combination of four compounds consisted of an anti-oxidant, an apoptosis inhibitor, an autophagy inhibitor and a protective growth factor. Increasing the number of factors to five or six resulted in decreased protection.…"

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx حسب Yutao Liu (87989)

"…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…"

Data Sheet 4_Metabolomics reveals key biomarkers for ischemic stroke: a systematic review of emerging evidence.pdf حسب Lu Ding (475637)

"…Increased tyrosine, glutamine, phenylalanine, sphingomyelin, glutamate, lactate and glucose, and decreased LysoPC (18:2), histidine, and methionine levels were linked to IS onset. …"

Table 1_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc حسب Xianghua Quan (21404606)

"…Dose intensity and reductions in white blood cell (WBC) counts were associated with the risk of OM. Furthermore, increased dose intensity, decreased WBC counts, and a history of cholelithiasis emerged as independent risk factors for the concurrent occurrence of HFS and OM.…"

Data source and description. حسب Yunxia Zhang (30848)

"…The results show that: (1) the level of non-grain of cultivated land in Lianyungang City increased gradually from 6.01% to 11.10% from 2002 to 2022, and grain cultivation was mainly shifted to greenhouse vegetables, construction and development and abandonment. (2) the level of non-grain of cultivated land showed a spatial pattern of high along the north-west-south-east and decreasing to the two sides, and the pattern showed a trend of gradual weakening, with Moran’s I decreased from 0.90 to 0.42. (3) The dominant factors of the spatial differentiation of non-grain of cultivated land in different periods are different, among which GDP, population density, NDVI, and precipitation are always the main influencing factors. …"

Table 3_Analysis of risk factors in breast cancer patients with hand-foot syndrome and oral mucositis caused by pegylated liposomal doxorubicin.doc حسب Xianghua Quan (21404606)

"…Dose intensity and reductions in white blood cell (WBC) counts were associated with the risk of OM. Furthermore, increased dose intensity, decreased WBC counts, and a history of cholelithiasis emerged as independent risk factors for the concurrent occurrence of HFS and OM.…"

Table_1_Combinatorial protection of cochlear hair cells: not too little but not too much.DOCX حسب Arwa Kurabi (344167)

"…The optimal combination of four compounds consisted of an anti-oxidant, an apoptosis inhibitor, an autophagy inhibitor and a protective growth factor. Increasing the number of factors to five or six resulted in decreased protection.…"

Analytical framework. حسب Yunxia Zhang (30848)

"…The results show that: (1) the level of non-grain of cultivated land in Lianyungang City increased gradually from 6.01% to 11.10% from 2002 to 2022, and grain cultivation was mainly shifted to greenhouse vegetables, construction and development and abandonment. (2) the level of non-grain of cultivated land showed a spatial pattern of high along the north-west-south-east and decreasing to the two sides, and the pattern showed a trend of gradual weakening, with Moran’s I decreased from 0.90 to 0.42. (3) The dominant factors of the spatial differentiation of non-grain of cultivated land in different periods are different, among which GDP, population density, NDVI, and precipitation are always the main influencing factors. …"

Data Sheet 1_Global, regional, and national time trends in falls and their predictions: an age-period-cohort analysis of the Global Burden of Disease Study 2021.pdf حسب Huan Jiang (1672375)

"…The cohort effect shows a trend of increasing first (RR: 1.02–1.18) and then decreasing (RR: 1.18–0.40). …"

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf حسب Faruk Hossen (20275670)

"…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …"

DataSheet1_Identification of common signature genes and pathways underlying the pathogenesis association between nonalcoholic fatty liver disease and heart failure.docx حسب Gerui Li (15648920)

"…Experimental validation indicated unbalanced macrophage polarization in HF and NAFLD mouse models, and the expression of CD163 and CCR1 were significantly down-regulated.</p>Conclusion<p>This study identified M2 polarization impairment characterized by decreased expression of CD163 and CCR1 as a common pathogenic pathway in NAFLD and HF. …"

Data Sheet 1_Plausibility of super high-flux dialyzer reuse in maintenance hemodialysis.pdf حسب Piyapun Prapunwatana (22474063)

"…Dialysate albumin loss decreased significantly from 1.01 g during the 1st use to 0.19 g during the 2nd and 0.06 g during the 5th use (p-value < 0.001). …"

Data Sheet 1_Prepandemic levels of cytokines and immunoglobulins and risk of SARS-CoV-2 infection and COVID-19 in the general population of Barcelona.docx حسب Miquel Porta (199379)

"…</p>Results<p>Higher concentrations in 2016–17 of IL-8 and TNF-α significantly decreased the risk of SARS-CoV-2 seropositivity in 2020–21, whereas higher concentrations of MIP-1α were a risk factor for seropositivity. …"

Data Sheet 1_Analyzing patterns of change in the orchid flora of Britain and Ireland with correlated environmental variability.pdf حسب Martha Charitonidou (798109)

"…Since recording began, the number of high diversity hotspots (SR ≥16 species) has decreased in Great Britain (from 107 to 41) and increased in Ireland (up to 6 from none), though many hotspots remain stable.…"

VB2 cell fate analysis of <i>hlh-17</i>, <i>hlh-31</i>, and <i>hlh-32</i> mutant animals. حسب G. Robert Aguilar (13889674)

"…Error bars indicate standard deviation of the mean. ****<i>p</i> ≤ 0.0001, *<i>p</i> ≤ 0.05, ns: not significant. …"