Glycogen synthase kinase 3 promotes the proliferation of porcine epidemic diarrhoea virus by phosphorylating the nucleocapsid protein by Xiangchao Jia (21392720)

“…The phosphorylation level significantly decreased after mutation of threonine (Thr) to serine (Ser). …”

High-throughput single-cell analysis reveals Omp38-specific monoclonal antibodies that protect against <i>Acinetobacter baumannii</i> infection by Yiwei Zhang (1448599)

“…Intravenous administration of the Omp38-specific mAbs significantly improved the survival rate and reduced the bacterial load in a mouse model of lethal <i>A. baumannii</i> infection. …”

Data Sheet 1_The response regulator CrsR positively regulates ansamitocin P-3 biosynthesis in Actinosynnema pretiosum.docx by Peipei Zhang (1360440)

“…Deletion of the response regulator gene crsR drastically decreased AP-3 production. RNA-seq revealed CrsR’s global regulatory role, significantly altering transcription of primary metabolic genes, especially those in purine metabolism. …”

Further characterization of N19 and calcium dependence. by Elham Karamooz (2584474)

“…<p>(<b>A</b>) N19 decreases MR1 presentation of Mtb when added at the same time as infection. 25µM N19 was added to BEAS-2Bs the same time as Mtb (MOI 8). …”

Data Sheet 1_The CML experience to elucidate the role of innate T-cells as effectors in the control of residual cancer cells and as potential targets for cancer therapy.pdf by Amandine Decroos (20222913)

“…Perforin, a key cytotoxic immune player, was expressed in a significantly higher proportion of both innate CD8 T-cell and NK-cell subsets in non-relapsed patients, compared with relapsed patients at D0. …”

Image 2_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Molecular characterization of zinc metalloproteinase Nas-14 from Trichinella spiralis and its participation in intestinal invasion by Qingbo Lv (21676001)

“…In addition, the direct incubation of rTsNas14 with claduin-1 showed that rTsNas14 could significantly degrade claudin-1. In vivo studies have demonstrated that inhibition of TsNas14 expression significantly impairs the infectivity of T. spiralis in mice, resulting in a decreased AW and muscle larval burden. …”

Image 1_Impaired K48-polyubiquitination downmodulates mouse norovirus propagation.tiff by Emmrich Wakeford (21249104)

“…Consequently, the number of viral genome copies or viral titers were also significantly decreased in the YFP-Ubiquitin_K48R cells compared to the YFP-Ubiquitin_WT cells. …”

Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

“…Additionally, gene and protein expression levels of P-glycoprotein (P-gp) and organic cation transporter 1 (OCT1) were assessed to explore the mechanisms by which HH affects pitolisant’s pharmacodynamics.</p>Results<p>A 40 mg/kg dose of pitolisant significantly improved learning, memory, cognitive, and motor functions in sleep-deprived mice under HH conditions (P < 0.05). …”

Raw data WB.pdf by Grazia Serino (21164993)

“…Moreover, miR-369-3p significantly decreased the release of pro-inflammatory cytokine IL-8. …”

Oligonucleotides used for vector clone. by Mingyi Xu (5575871)

“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

Information of chemicals used in this study. by Mingyi Xu (5575871)

“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

Oligonucleotides used for amplification. by Mingyi Xu (5575871)

“…In this work, we found that RNA2.7 deletion significantly decreased the viability of HCMV-infected cells, while treatment with ferroptosis inhibitor Fer-1 rescued the infection-induced cell death, demonstrating an anti-ferroptosis role of RNA2.7. …”

Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025 by Alexandre Berthier (16876311)

“…</p><h3>Results</h3><p dir="ltr">Our study shows that temporarily blocking the insulin receptor in young mice leads to later-life liver issues by hindering PPARα-mediated adaptation to a high-fat diet. This is linked to decreased histone active marks at PPARα sites and reduced endogenous PPARα ligands. …”

The effect of Tawny crazy ants on the abundance of aboveground insect abundance in Texas by Ryan Reihart (9174179)

“…We also found that in areas where <i>N. fulva </i>were abundant, there was a significantly greater abundance of honeydew-producing hemiptera from the Cicadellidae family, which is a likely factor aiding in the dominance and further spread of <i>N. fulva</i>. …”

Disruption of <i>CmHmgr1</i> triggers apoptosis and causes defects in growth, conidiogenesis, and mycoparasitism of <i>Coniothyrium minitans</i> by Xiaoxiang Yang (5945225)

“…This mutant exhibited significantly reduced hyphal development, poor conidiation, and decreased sclerotial mycoparasitism. …”

Table 4_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls by Genet Atsbeha (17595417)

“…The majority of the discovered resistance quantitative trait loci (QTLs) were located on the same chromosomes as previously reported QTLs for yellow rust resistance, specifically on chromosomes 1A, 1B, 2A, 2B, 2D, 3A, 3B, 3D, 5A, 5B, 5D, 6A, 6B, 6D, 7A, 7B, and 7D. …”

Table 5_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls by Genet Atsbeha (17595417)

“…The majority of the discovered resistance quantitative trait loci (QTLs) were located on the same chromosomes as previously reported QTLs for yellow rust resistance, specifically on chromosomes 1A, 1B, 2A, 2B, 2D, 3A, 3B, 3D, 5A, 5B, 5D, 6A, 6B, 6D, 7A, 7B, and 7D. …”

Table 6_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.xls by Genet Atsbeha (17595417)

“…The majority of the discovered resistance quantitative trait loci (QTLs) were located on the same chromosomes as previously reported QTLs for yellow rust resistance, specifically on chromosomes 1A, 1B, 2A, 2B, 2D, 3A, 3B, 3D, 5A, 5B, 5D, 6A, 6B, 6D, 7A, 7B, and 7D. …”

Table 2_Genome-wide association study of seedling–plant resistance to stripe rust in bread wheat (Triticum aestivum L.) genotypes.doc by Genet Atsbeha (17595417)

“…The majority of the discovered resistance quantitative trait loci (QTLs) were located on the same chromosomes as previously reported QTLs for yellow rust resistance, specifically on chromosomes 1A, 1B, 2A, 2B, 2D, 3A, 3B, 3D, 5A, 5B, 5D, 6A, 6B, 6D, 7A, 7B, and 7D. …”