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significantly increased » significant increase (Expand Search)
increased decrease » increased release (Expand Search), increased crash (Expand Search)
small decrease » small increased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
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12641
Alteration of Ubiquitination in the Brain of ENOPH1 Knockout Mice after Early Ischemic Stroke
Published 2025“…Our results showed that 4000 ubiquitination-modified sites in 1613 proteins were quantified, with 772 ubiquitinated sites in 464 proteins significantly decreasing or increasing after ENOPH1 knockout (fold change >1.5 or <1/1.5, <i>p</i> < 0.05). …”
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12642
Data Sheet 1_Distribution of different plant life forms on tropical islands: patterns and underlying mechanisms.docx
Published 2025“…</p>Results<p>The results indicate that species richness increases with island area and decreases with isolation, which aligns with the classic predictions of island biogeography. …”
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12643
Data Sheet 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf
Published 2025“…Introduction<p>Kidney allograft fibrosis accelerates the progression of chronic kidney disease (CKD), leads to allograft failure, and increases patient mortality. Emerging evidence suggests that metabolic syndrome in transplant recipients is associated with fibrosis development. …”
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12644
Data Sheet 4_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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12645
Table 3_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
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12646
Data Sheet 1_Acupoint catgut embedding alleviates experimental autoimmune encephalomyelitis by modulating neuroinflammation and potentially inhibiting glia activation through JNK a...
Published 2025“…The ACE treatment restored immune imbalance in the EAE mice by decreasing Th17 and Th1 cells, while increasing Treg cells in peripheral immune organs and reducing serum inflammatory cytokine levels. …”
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12647
Health Risks of Low-Dose Dietary Exposure to Triphenyl Phosphate and Diphenyl Phosphate in Mice: Insights from the Gut–Liver Axis
Published 2025“…TPHP intake affected the levels of short-chain fatty acids and bile acids in the gut, enhancing the production of 29 medium- and long-chain fatty acids in the liver by 3.72-fold and significantly increasing hepatic lipid and cholesterol levels. …”
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12648
Table 1_Esmolol improves sepsis outcomes through cardiovascular and immune modulation.docx
Published 2025“…Additionally, Esmolol treatment resulted in bidirectional regulation of T-cell counts, increasing CD4<sup>+</sup> and CD8<sup>+</sup> T-cell counts in patients with higher baseline immune function and decreasing these counts in patients with lower baseline levels (P < 0.01).…”
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12649
Table 2_Global, regional and national patterns and gender disparity of intraocular foreign bodies from 1990 to 2021.doc
Published 2025“…The increase in the all-age DALYs of IOFBs was lowest compared with other eye diseases in GBD 2021. …”
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12650
Data Sheet 1_Inhibition SIRT1 to regulate FOXP3 or RORγt can restore the balance of Treg/Th17 axis in ulcerative colitis and enhance the anti-inflammatory effect of moxibustion.pdf...
Published 2025“…Finally, in vivo studies, the results have shown that administering EX-527 to inhibit SIRT1 leads to an increasing in FOXP3 expression and a decreasing in RORγt expression in UC colon tissue. …”
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12651
Table 5_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”
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12652
Data Sheet 1_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx
Published 2025“…</p>Results<p>Post-COVID-19, there was a significant increase in the scores for theoretical knowledge (77.10 ± 14.83 vs. 63.10 ± 15.11, p < 0.001) and understanding of infectious disease regulations (54.78 ± 15.94 vs. 50.85 ± 12.52, p = 0.001) among grassroots hospital physicians compared to pre-COVID-19 levels, albeit with room for further improvement. …”
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12653
Table 1_ADAM8 in macrophages exacerbates sepsis-induced cardiomyopathy by impeding efferocytosis.docx
Published 2025“…Mechanistically, ADAM8 deficiency promoted macrophage efferocytosis by increasing phagocytic receptors (MerTK) while reducing soluble Mer (sMer) generation. …”
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12654
Table 4_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx
Published 2025“…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …”
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12655
Supplementary file 1_Effects of education level on natural language processing in cardiovascular health communication.xlsx
Published 2025“…</p>Results<p>Readability decreased significantly with increasing education level across all models (p < 0.001). …”
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12656
Data Sheet 1_Exploring the effects of exercise on T cell function and metabolism in cancer: a scoping review protocol.pdf
Published 2025“…This interaction may not only be linked to the benefits of exercise in decreasing cancer risk and increasing survival but may also have the potential to be harnessed to enhance current forms of immunotherapy. …”
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12657
Tanshinone I as a novel therapeutic agent targeting von Willebrand factor-binding protein to mitigate <i>Staphylococcus aureus</i> pathogenicity
Published 2024“…Our findings revealed that tanshinone I significantly inhibited vWbp-induced coagulation without affecting the proliferation of <i>S. aureus</i>. …”
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12658
Table 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.xls
Published 2025“…Introduction<p>Kidney allograft fibrosis accelerates the progression of chronic kidney disease (CKD), leads to allograft failure, and increases patient mortality. Emerging evidence suggests that metabolic syndrome in transplant recipients is associated with fibrosis development. …”
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12659
Data Sheet 5_The power of GM-CSF: immune regulation in the defense against Phialophora verrucosa infection.pdf
Published 2025“…</p>Results<p>Compared to WT mice, GM-CSF deficiency significantly delayed fungal clearance and prolonged disease progression, accompanied by reduced inflammatory responses and decreased neutrophil infiltration. …”
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12660
Table 2_Speckle tracking technology and investigation of risk factors for premature ventricular contraction-induced cardiomyopathy.pdf
Published 2025“…Regression analysis revealed that asymptomatic PVCs, paired/interpolated PVCs, wide QRS duration (≥150 ms), and higher PVC burden were significantly associated with decreased GLS and GCS magnitude. …”