Search alternatives:
significantly increased » significant increase (Expand Search)
significant binding » significant burden (Expand Search), significant benefits (Expand Search)
increased decrease » increased release (Expand Search), increased crash (Expand Search)
binding decrease » binding database (Expand Search)
significantly increased » significant increase (Expand Search)
significant binding » significant burden (Expand Search), significant benefits (Expand Search)
increased decrease » increased release (Expand Search), increased crash (Expand Search)
binding decrease » binding database (Expand Search)
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Impact of Gemin5 in protein synthesis: phosphoresidues of the dimerization domain regulate ribosome binding
Published 2025“…We show that the activation of signalling pathways in response to a dsRNA mimic, which leads to phosphorylation of eIF2α, enhanced the intensity of Gemin5 binding to a cognate RNA ligand. In addition, ribosome binding decreased when Ser/Thr 847 and 852–854 are substituted by a non-phosphorylatable residue, consistent with decreased protein stability, and reduced number of associated factors. …”
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1932
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<b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b>
Published 2025“…Age-corrected data revealed decreased islet frequency and increased inter-islet distances in the type 1 diabetes pancreas. …”
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1937
Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx
Published 2025“…</p>Conclusion<p>This study integrated meta-analysis, murine model validation, and single-cell transcriptomic profiling to demonstrate a significant reduction of BDNF in CKD. Furthermore, renal BDNF expression decreased locally, predominantly originating from proximal tubule cells, macrophages, and podocytes, possibly epigenetically inhibited by the upregulation of lnc RNA Bdnf-as.…”
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