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significantly increased » significant increase (Expand Search)
significant decrease » significant increase (Expand Search)
increased decrease » increased release (Expand Search), increased crash (Expand Search)
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19961
Data Sheet 2_Effects and safety of Salvia miltiorrhiza on the improvement of renal function, inflammatory factors, and vascular endothelium in patients with diabetic kidney disease...
Published 2025“…Notably, the safety profile remained sound, with no significant differences in adverse event rates between the two groups (P > 0.05).…”
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19962
Presentation_1_Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunc...
Published 2024“…This research study is significant as it aims to assess the neuroprotective properties of vitamin E (VE) analog Trolox in an Aβ<sub>1 − 42</sub>-induced AD mouse model. …”
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19963
Table 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.xlsx
Published 2025“…ARL5B expression was significantly downregulated in treated Y79 and Weri-RB1 cells. …”
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19964
Image5_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellula...
Published 2024“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”
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19965
Data Sheet 1_Deep learning-based image reconstruction benefits diffusion tensor imaging for assessing severity of depression.docx
Published 2025“…</p>Results<p>Twenty-eight patients with mild-to-moderate depression and 24 with severe depression were included. No significant differences were observed between the two groups in terms of gender (p = 0.115), age (p = 0.603), or educational background (p = 0.148). …”
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19966
Table 2_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx
Published 2025“…Crim1 encodes a type I transmembrane protein that is expressed at the cell membrane of lens epithelial and fiber cells at the stage of lens pit formation. Decreased Crim1 expression in the mouse reduced the number of lens epithelial cells and caused defective adhesion between lens epithelial cells and between the epithelial and fiber cells.…”
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19967
Table 1_Real-world first-line serplulimab therapy for advanced esophageal cancer: effectiveness, safety, and clinical implications.docx
Published 2025“…Objective<p>The phase III ASTRUM-007 trial demonstrated significant clinical benefit in patients with PD-L1-positive esophageal squamous cell carcinoma (ESCC) treated with first-line serplulimab plus chemotherapy. …”
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19968
Table 1_Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center.docx
Published 2025“…TMA event-free status was reached in 15 (63%) patients. Significant improvements were observed in platelet count (63%), lactate dehydrogenase levels (76% within the first week), hemoglobin (60%), and estimated glomerular filtration rate (79%); while CH-50 levels decreased. …”
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19969
Image10_Integrating anoikis and ErbB signaling insights with machine learning and single-cell analysis for predicting prognosis and immune-targeted therapy outcomes in hepatocellul...
Published 2024“…Background<p>Hepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. …”
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19970
Table1_Causal association between matrix metalloproteinases and diabetic neuropathy: a two-sample Mendelian randomization study.docx
Published 2025“…Objective<p>Diabetic neuropathy (DN), a common and debilitating complication of diabetes, significantly impairs the quality of life of affected individuals. …”
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19971
Data - <i>trus</i>RNAi wing size measurement.
Published 2025“…In mutant larvae, we found decreased cell proliferation and growth defects in the brain and imaginal discs. …”
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19972
Characteristics of children in the study.
Published 2025“…</p><p>Conclusions:</p><p>This study found a significant association between myopia and worse HRQOL in primary and secondary school children. …”
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19973
Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx
Published 2025“…Among 15 lupus nephritis patients, 86.7% achieved complete renal response. Significant hematologic improvement was observed in autoimmune hemolytic anemia and thrombocytopenia. …”
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19974
Image 3_Changes in symptom pattern in Meniere's disease by duration: the need for comprehensive management.tif
Published 2024“…The frequency and duration of vertigo attacks generally decreased over time, with attacks becoming shorter and less severe as the disease progressed. …”
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19975
Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i>
Published 2025“…Research has shown that the absence of Cdc4, an F-box protein in <i>C. neoformans</i>, decreases virulence, yet the mechanisms by which Cdc4 affects these processes remain unclear. …”
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19976
Image 1_Safety assessment of temozolomidee: real-world adverse event analysis from the FAERS database.png
Published 2025“…Notable PTs included *petechiae* (ROR 9.87), *hemiparesis* (ROR 9.36), and *platelet count decreased* (ROR 8.61). Unexpected AEs, such as *pulmonary embolism* (ROR 4.96) and *Pneumocystis jirovecii pneumonia* (ROR 7.09), were identified. …”
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19977
<i>mig-21</i> sensitizes adult DTCs to polarizing signals.
Published 2025“…However, migration cessation is not rescued; a significant increase in “overmigration” defects is observed between marked control (n=4/57) and <i>mig-21(u787)</i> on <i>vab-3</i> RNAi (n=17/65), p < 0.05. …”
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19978
Excel raw data.
Published 2025“…The effectiveness of currently available antimicrobial is decreasing due to the increasing prevalence of resistant strains among bacterial isolates. …”
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19979
Digitized maps of vascular plant species distributions in Denmark in the early 20th century
Published 2025“…By comparing with modern distribution data, species increases and decreases can be determined, contributing to large-scale synthesis of national, European or worldwide plant diversity changes in the modern era.…”
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19980
<b>Distributed Hydraulic Micro-Cooling (MHD): A Low-Cost, High-Impact Urban Heat Mitigation Strategy</b> / <b>Enfriamiento Hidráulico Micro-Distribuido (MHD): Estrategia Urbana de...
Published 2025“…Large thermal masses such as roofs, asphalt roads, and concrete structures store significant amounts of solar radiation during the day (up to 1200–1600 MJ/m²). …”