Research instrument validation. by Jing Zhu (27724)

“…</p><p>Results</p><p>The results confirmed that emotional exhaustion and organizational identification are crucial mediators. Three significant indirect pathways were identified: (1) a simple mediation path through emotional exhaustion; (2) a simple mediation path through organizational identification; and (3) a chained mediation path where job insecurity increased emotional exhaustion, which in turn decreased organizational identification, ultimately leading to lower OCB. …”

Competition constrains the resistance and recovery of fungi to heat stress under low nutrient concentration by Jingjing Shi (20738168)

“…Specifically, competition decreased the recovery of <i>M. elata</i> and the resistance of <i>T. atroviride</i> under low nutrient concentration. …”

Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…The primary outcomes included relapse rates, Expanded Disability Status Scale (EDSS) scores, and survival outcomes.</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Image 2_Bacterial peptidoglycan levels have brain area, time of day, and sleep loss-induced fluctuations.jpg by Erika L. English (21725081)

“…After 3 h of sleep disruption, PG levels increased in the somatosensory cortex, but decreased in brainstem, and hypothalamus. …”

Supplementary Material for: Status of inpatients with pediatric epilepsy in children’s hospitals in China (2016–2021) by Wang J. (3112815)

“…The disease burden decreased from 17.26% to 12.11% with a significant upward trend (P=0.02417, R2=0.8817). …”

QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells by Neha Laxane (19851759)

“…</p> <p>Protamine coating was clearly visible on images using transmission electron microscopy analysis.</p> <p>Significant reduction in IC₅₀ values showing increased cytotoxicity was observed.…”

Data Sheet 3_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.csv by Jiaxin Wu (540397)

“…Notably, both strains demonstrated decreased unsaturated lipid intensity alongside increased malondialdehyde levels—a key oxidative stress marker. …”

Data Sheet 2_The impact of sublethal antimicrobial blue light on lipidomic changes of Escherichia coli and Salmonella Typhimurium.csv by Jiaxin Wu (540397)

“…Notably, both strains demonstrated decreased unsaturated lipid intensity alongside increased malondialdehyde levels—a key oxidative stress marker. …”

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Reduced Aqueous Retinol Binding Protein 3 Concentration is Associated with Diabetic Macular Edema and Progression of Diabetic Retinopathy by Tanvi Chokshi (12970453)

“…Aqueous RBP3 decreased from a median of 2.1nM [IQR 0.8-3.4nM] in eyes with no DR to 1.5nM [0.8-3.8nM] in eyes with mild-moderate NPDR (P=0.047). …”

Evolutionarily conserved and functionally important amino acids in Artemis. by Ziwen Huang (17562948)

“…<b>(D)</b> Several mutations of human Artemis found in ClinVar decreased its activity in CJ formation after cleavage of MmuRAG1/2 in 293T^{<i>Artemis−/−</i>} cells. …”

Supplementary Material for: Retrospective Analysis of Allergen Characteristics in Patients with Allergic Diseases in Sanmen, Zhejiang Province by figshare admin karger (2628495)

“…The serum total IgE positivity rate was highest in the ≤12 age group and declined with age, with a resurgence observed in individuals over 60. Similarly, the positivity rates for Dermatophagoides spp. allergens and cow's milk also decreased with age. …”

Height and canopy measurements of native shrubs in southern California by Emma Underwood (22077698)

“…We identified four key findings: (1) shrub biomass increased with time since last fire and the proportion of resprouting species, and decreased with distance to coast and solar radiation; (2) species with the ability to resprout (obligate resprouter and facultative seeders) contributed greater biomass at all post-fire time periods and locations when compared with obligate seeders; (3) we found higher average biomass contributed by both obligate seeder and obligate resprouter species in plots closer to the coast than interior plots; and (4) fourth, we found a significant positive relationship between woody shrub richness and biomass. …”

Fig 4 - by Helene Dumont (19812720)

“…</b> A difference is significant when the CrI of the parameters of the inversion effect (blue) and negation effect (yellow) do not overlap. …”

Thymoquinone loaded nanoemulgel in streptozotocin induced diabetic wound by Urati Anuradha (20306190)

“…</p> <p>In diabetic wound animal model nanoemulgel showed significant decreased levels of TNF-α, IL-6, MMP-9 and IL-1β. …”

<p></p><p></p><p dir="ltr"><b>Trends in GP dispensing of thickeners in the NHS England, 2019-24</b></p> by ARLENE MCCURTIN (22819052)

“…Thickened liquids is primarily an intervention for older people although there was a significant decreasing trend in dispensed thickener items in adult populations. …”

Figure 4 from Impact of Glucocorticoids on Immune Checkpoint Inhibitor Efficacy and Circulating Biomarkers in Non–Small Cell Lung Cancer Patients by Lauren Polyakov (21672045)

“…<p>Continued use of corticosteroids during anti–PD-L1 therapy correlates with decreased survival in a preclinical model. …”

Internal states adjust the Brp compartmental heterogeneity through octopamine. by Hongyang Wu (8856740)

“…<b>(C)</b> Sleep deprivation for 12 h decreases Brp::rGFP heterogeneity level in a <i>T</i>β<i>h-</i>dependent manner. …”