Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf by Nineth Rossi (22355524)

“…Introduction<p>Long COVID and post-COVID syndromes represent a significant global health crisis and a substantial societal challenge. …”

Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Image1_Characterization of GABAergic marker expression in prefrontal cortex in dexamethasone induced depression/anxiety model.jpeg by Ling Hu (374570)

“…Furthermore, DEX treatment reduced the expression levels of a GABA-synthesizing enzyme (GAD67), Reelin, calcium-binding proteins (parvalbumin and calretinin) and neuropeptides co-expressed in GABAergic neurons (somatostatin, neuropeptide Y and vasoactive intestinal peptide) in the PFC were reduced after 21 days of DEX treatment; these reductions were accompanied by decreases in brain size and cerebral cortex thickness.…”

Table 1_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Table 4_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Table 2_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Table 3_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…(<b>F</b>) Brightfield images of wild type (f1), control <i>Notch3</i> heterozygote (f2) compared to homozygote <i>Nodal</i> mutants with decreased <i>Notch3</i> (f3) at E9.5, in a ventral view. …”

supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…(right): Self-renewal capacity of RD and AD-RD cells assessed by a sphere formation assay (n = 4). Statistical significance: ****p < 0.0001. c (top): Immunoblots from in vitro kinase assays treated with hit compounds and with EGFR inhibitors. …”

Supplementary file 1_Tapered fiber probe-based optical cardiac pacemaker.docx by Yanzheng Xie (22596953)

“…Calcium imaging confirmed a photothermal mechanism wherein optical absorption of irradiated myocardial tissue activates thermosensitive protein channels, triggering calcium ion influx and subsequent depolarization.…”

Changes in Culicoides sonorensis feeding behavior following sublethal insecticide exposure by Parker Mullins (22079690)

“…We identified a significant inhibition of engorgement by permethrin up to 12 hours post-exposure, as well as by fluralaner up to 6 hours post-exposure. …”

Readiness Through International Cooperation: Finnish Defence Industrial Strategy in Changing Operational Environment from the Mid-1990s to the Early 2020s by Heikki Roiko-Jokela (22265501)

“…<p>After the Cold War, European defence industrial capacity decreased; however, in the 2020s, there is again a need for products of the defence industry. …”

Figure 7 from KDM6 Demethylases Contribute to EWSR1::FLI1-Driven Oncogenic Reprogramming in Ewing Sarcoma by Elisabet Figuerola-Bou (22618659)

“…<p>KDM6B KO decreases tumor growth. <b>A,</b> Colony formation assay of KDM6B KO cells (sgRNA#1 and sgRNA#2) compared with parental and sgCTRL A-673 cells. …”

Additional file 2 of Evobrutinib mitigates neuroinflammation after ischemic stroke by targeting M1 microglial polarization via the TLR4/Myd88/NF-κB pathway by Yixiang Jiang (2580220)

“…Statistical analysis revealed no significant differences in CD80+ expression between MCAO and Evobrutinib group while the expression of MHCII+ microglia decreased in Evobrutinib group compared to MCAO. …”

PTEN KD induces EMT in epithelial CRC cells. by Ahmed H. Ghobashi (12705573)

“…EZH2i treated EV and PTEN KD cells act as a control for decreased H3K27me3 levels. <b>(C)</b> H3K27me3 band quantification for untreated EV and PTEN KD in HT29 and LS174T cells in (B). …”

Data Sheet 1_Modeling lymphocyte subset dynamics after ublituximab therapy in patients with multiple sclerosis: an Italian prospective study.pdf by Aurora Zanghì (9202094)

“…Mixed-effects models showed a significant effect of time on all lymphocyte subsets. …”

Statistical data. by Bo Yang (104813)

“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”

Sensitivity of land types to threat factors. by Bo Yang (104813)

“…The results show that: (1) Habitat quality shows significant gradient characteristics, and the overall decreases from southeast to northwest. …”

Figure 2 from Loss of Sorting Nexin 10 Accelerates KRAS-Induced Pancreatic Tumorigenesis by Kohinoor Khan (22206206)

“…<p>OE of SNX10 decreased cell proliferation in AsPC1 and HPAF-II PDAC cell lines. …”