Table3_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Image 3_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... by Khalidah Ibraheem (9525220)

“…Optimal cooling at 18°C rescued cell viability, significantly (p < 0.001) restored HF proliferation (42% Ki-67+ cells) and pigmentation, suppressed apoptosis (10% TUNEL+ cells), restored anagen (∼70%) and induced a 2-3-fold increase in hair shaft elongation (p < 0.001), whereas cooling at 26°C was only partially effective. …”

All data. by Ke Li (106849)

“…Metabolomics analysis revealed that inulin treatment significantly modulated the levels of 8 stage-specific metabolites; notably, it increased anti-inflammatory, anti-diabetic and neuroprotective metabolites taurine and dodecanoic acid in prediabetic mice, while decreasing pro-inflammatory mediators including oleamide and adrenic acid. …”

Data Sheet 4_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 5_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 1_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 3_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Data Sheet 2_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dependent g... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

Supplementary file 1_Sirtuin 6 mediates the therapeutic effect of endometrial regenerative cell-derived exosomes in alleviation of acute transplant rejection by weakening c-myc-dep... by Tong Liu (107783)

“…Furthermore, in the recipient mice, ERC-Exo treatment markedly increased the differentiation of regulatory T cells (Tregs) while significantly decreasing that of Th1 and Th17 cells. …”

DataSheet2_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.docx by Marek Sierzega (3846406)

“…Differentially expressed proteins and 5 myokines with increased serum levels generated a significant protein-protein interaction network.…”

DataSheet3_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.xlsx by Marek Sierzega (3846406)

“…Differentially expressed proteins and 5 myokines with increased serum levels generated a significant protein-protein interaction network.…”

DataSheet1_Dissecting the importance and origin of circulating myokines in gastric cancer cachexia.docx by Marek Sierzega (3846406)

“…Differentially expressed proteins and 5 myokines with increased serum levels generated a significant protein-protein interaction network.…”

SERCA is required for Ca²+ transients at E5.5. by Matthew J. Stower (22379321)

“…DMSO treated embryos had a significant decrease in transients (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test; baseline vs. 30 min DMSO <i>p</i> > 0.05), but thapsigargin almost completely abolished transients to a significant effect (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test, baseline vs. 30 min 10 nM thapsigargin <i>p</i> ≤ 0.001), that was significantly lower than DMSO controls (one-way ANOVA, <i>p</i> ≤ 0.001, followed by Tukey’s HSD Test, 30 min DMSO vs. 30 min 10 nM thapsigargin: <i>p</i> ≤ 0.001). …”

Data Sheet 1_Effects of compound fermentation with Limosilactobacillus fermentum HHL-5 and citric acid on wilted king grass silage.pdf by Ying Dou (45956)

“…Lactic acid and acetic acid contents were significantly increased in the LCA group (p < 0.05), whereas lactic acid content was increased and acetic acid content was significantly decreased in the L group (p < 0.05). …”

Table 1_Research on the effect of Rosa roxburghii root in alleviating spleen and stomach damp–heat gastric ulcer by regulating the imbalance of oral–gut axis microbiota.xlsx by Jiangsong Cao (22580375)

“…Following ulcer onset, decreased levels of NO, iNOS, PGE₂, and MTL, alongside increased levels of TNF-α, IL-6, and MDA, directly induce a reduction in the abundance of bacteria, including Rothia, Streptococcus, Corynebacterium, Globicatella, Romboutsia, and Lactobacillus, with this effect being more pronounced in the oral cavity. …”

Data Sheet 1_Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling.docx by Lanlan Sun (1798921)

“…Additionally, the combination of CSA and Clo reduced MDA levels by 13.4%, increased SOD activity by 9.7% and GST activity by 26.7%, while elevating GSSG content by 31.3% compared to Clo alone, ultimately mitigating oxidative damage in maize plants. qRT-PCR analysis showed that the expression of five P450 genes (CYP72A5, CYP81A4, CYP81Q32, CYP81A9, CYP81A36), nine GST genes (GST30, GST31, GSTIV, GSTVI, GST21, GST7, GST37, GST25, IN2-1), and two UGT genes (UGT76C2, UGT83A1) significantly high increased by 6.74-, 10.27-, 4.98-, 10.56-, 25.67-, 16.70-, 46.92-,7.53-, 5.10-, 238.82-, 143.50-, 4.58-, 31.51-, 39.3-, 4.20-, 10.47-fold after CSA+Clo treatment compared to that in the Clo treatment. …”

Data Sheet 1_Longitudinal changes in bodyweight, body condition, and muscle condition in ageing pet cats: findings from the Cat Prospective Ageing and Welfare Study.docx by Christine R. Pye (22118977)

“…All three metrics showed significant non-linear associations with age. Bodyweight increased slightly from age 7 to 10 (estimated marginal mean 4.77–4.82 kg) before decreasing to 4.30 kg by age 16 years. …”

Human Wharton’s jelly-derived mesenchymal stem cells (hWJ-MSCs) and recombinant growth regulated oncogene-alpha (GRO-α) inhibit necroptosis in an mdx mice model. by Sang Eon Park (11243760)

“…The CK levels were significantly decreased in the hWJ-MSC-injected and GRO-α-treated groups. …”

Table 4_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf by Ziqin Feng (22318243)

“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”

Table 2_Transcriptomic analysis reveals the key role of inflammatory and immune signaling in the anti-perimenopausal depression effects of Bushen Shugan Huayu decoction.pdf by Ziqin Feng (22318243)

“…</p>Results<p>Following BSSGHY decoction treatment, patients showed a significant reduction in HAMD scores (p < 0.01), marked symptom relief (p < 0.05), and decreased inflammatory factor levels (p < 0.01). …”