Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

“…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”

Reinforced steering Evolutionary Markov Chain for high-dimensional feature selection by Atiq ur Rehman (3044409)

“…(v) The effective size of successful agents is reduced recursively while progressing through different states to further facilitate the speed of convergence and decrease the number of features. (vi) The performance comparison with state-of-the-art feature selection methods shows a significant improvement and promise of the proposed method over the existing methods.…”

Comparison of Myeloid Cells in Circulation and in the Tumor Microenvironment of Patients with Colorectal and Breast Cancers by Salman M. Toor (8854751)

“…We found that both PBC and CRC patients have significantly higher levels of granulocytic and immature myeloid cells in the TME. …”

Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

“…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”

KINETIC DOUBLE SKIN FAÇADE AS AN ENVIRONMENTALLY RESPONSIVE STRATEGY TO REDUCE ENERGY AND IMPROVE LIGHT COMFORT IN AN OFFICE BUILDING IN DUBAI - UAE by ALSALEEM, MOAMIN

“…CFD software used to measure the stack effect of the double skin, and the simulation concurs the disadvantage of high rise scale of double skin façade due to chimney effect factor where wind temperatures increased drastically. The Light performance simulated by Revit light analysis where the criteria of the test identified by scale useful daylight illuminance UDI factor and high level of illuminance HDI and below threshold light factor LDI. …”
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Dynamics of Muslim consumers’ behavior toward Halal products by Osama Sam Al-Kwifi (18061030)

“…</p><h3>Findings</h3><p dir="ltr">Across all participants, the level of brain activation in the ventromedial prefrontal cortex increased significantly when Halal images were presented to them. …”

Combined experimental and computational investigations of the fluorosolvatochromism of chromeno[4,3-b]pyridine derivatives: Effect of the methoxy substitution by Mohanad Shkoor (3768385)

“…The results obtained revealed a significant positive fluorosolvatochromism, with a bathochromic shift in the fluorescence spectrum as the solvent polarity increased. …”

Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

“…</p> <h3>Conclusions</h3> <p>This retrospective study demonstrated that neonates of hypertensive mothers have significant differences in gestational age at birth, birthweight, occurrence of respiratory distress and prematurity. …”

Natural resource dependence and war nexus: new insights by Al Shami, Farah

“…Using a panel probit model, we find that natural resources rents, military expenditures, and the presence of a common law tradition significantly increase the probability of war occurrence. …”
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Voluntary Adoption of Integrated Reporting in an Emerging Market: The Case of UAE by KURDY, DANIA MAHMOUD

“…The study assessed firm-level factors such as profitability, leverage, size, age, and industry, alongside board-level factors including independence, gender diversity, and size. …”
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Improving the Resilience of Smart Distribution Networks against Cyber Attacks by ElYamani, Mohamed ElHusseiny Mohamed

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A combined experimental and computational study of the effect of electron irradiation on the transport properties of aromatic and aliphatic molecular self-assemblies by Y. Tong (18394389)

“…This structural modification also results in a significant decrease of the current. These findings can be useful in understanding the processes during the electron irradiation of molecular SAMs.…”

Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…We characterized variants in <i>CCL5</i> and that of six other CCL5 signaling genes (<i>CCND1, ZMIZ1, CASP8, NOTCH2, MAP3K21, and HS6ST3</i>) among 1,082 unrelated Tunisian subjects (544 BC patients, including 196 TNBC, and 538 healthy controls), assessed the association of the variants with BC-specific overall survival (OVS) and progression-free survival (PFS), and correlated CCL5 mRNA and serum levels with <i>CCL5</i> genotypes. We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”

Effects of statins on clinical outcomes in hospitalized patients with community-acquired pneumonia by Zeenny, Rony M.

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Effects of polyphenol‐rich traditional herbal teas on obesity and oxidative stress in rats fed a high‐fat–sugar diet by Neelam Iftikhar (14778400)

“…Higher doses of <i>Hibiscus rosa-sinensis</i> significantly decreased the levels of AST, ALT, AP, and SC in comparison with the HFSDC group. …”

Beyond the needle: How nonsurgical management transforms foot and ankle ability in male footballers with posterior ankle impingement- a longitudinal study by Gupta, Jyoti

“…Tenderness and ROM showed significant changes after 4 and 8 weeks. The FAAM% score significantly increased (p < 0.001) after 8 weeks, reflecting enhanced overall functional ability. …”
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DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation by Abdelilah Arredouani (10914455)

“…Using JNK1- and IKKβ-dependent luciferase reporters, we show a marked decrease in luciferase activity by DNAJB3 in response to PMA and TNF-α that was consistent with a decrease in the translocation of p65/NF-κB to the nucleus in response to LPS. …”

Effects of organic enrichment on macrofauna community structure: an experimental approach by Rodrigo Riera (10476249)

“…A reduction in abundance of individuals and species richness was found as between the control and organic-enriched treatments. Significant changes in assemblage structure were also found, mainly due to the decrease of the sensitive tanaid Apseudes talpa in organically-enriched treatments. …”

Cognition and physical functioning in patients with schizophrenia: any role for vitamin D? by Azar, Jocelyne

“…Severe VD deficiency was significantly associated with an increase in MRSS score after adjusting for covariates (Beta = 2.44), however, no significant association was found with the BCRS score. …”
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Effect of Climate Change on the Energy Performance and Thermal Conditions of a Single-family Detached House in Canada by Mutasim Baba, Fuad

“…These measures will significantly reduce the energy consumption of buildings. …”
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