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81
IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells
منشور في 2002"…Neither IL-1 nor ceramide induced apoptosis in IEC, but they increased bcl-2 levels and decreased bax and p21 levels without affecting bcl-x and p53 levels. …"
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82
Long-term antibiotic resistance surveillance of gram-negative pathogens suggests that temporal trends can be used as a resistance warning system
منشور في 2002"…Resistance levels for norfloxacin showed the same high statistical significance in terms of the temporal trend. …"
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83
Meal pattern of male rats maintained on histidine-, leucine-, or tyrosine-supplemented diet.
منشور في 2007"…Both histidine and tyrosine supplementation elevated fasting plasma insulin levels and suppressed fasting glucose significantly. …"
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84
Reducing injuries among young drivers: what kind of measures are needed?
منشور في 2015"…Keskinen (1996) divided the task of driving into four separate levels (4. goals for life and skills for living, 3. goals and context of driving, 2. mastering traffic situations and 1. vehicle maneuvering) in which the higher levels are considered to always affect behavior on the lower levels.The idea behind a hierarchical approach is that success as well as failure on the higher levels will affect the demand on lower levels (Hatakka et al. 2002). …"
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85
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
منشور في 2025"…The most common symptoms reported were fatigue, dizziness, and pallor. Hemoglobin levels significantly increased from 6.4 to 11.1 g/dl (<i>p</i> < 0.001) after IV iron treatment, as did ferritin levels, while total iron-binding capacity decreased. …"
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86
Immunoprofile of childhood diabetes
منشور في 2023"…<p><strong>Poster by Meritxell Espino-Guarch (Sidra Medicine), Rana Nahas (Sidra Medicine), Taushif Khan (Sidra Medicine), Susi Huang (Sidra Medicine), Anna Halama (Weill Cornell Medicine-Qatar), Khalid Hussain (Sidra Medicine), and Nicholas van Panhuys (Sidra Medicine)</strong></p> <p>Background: The incidence of T2D has increased significantly in recent years and is characterized by impaired insulin secretion, glucose intolerance and hyperglycemia and is highly associated with a modern sedentary lifestyle and obesity. …"
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87
Corporate Governance, Disclosure Content and Shareholder Value
منشور في 2013"…Banks market capitalisation dropped significantly, risk levels increased and stakeholders’ confidence was shaken. …"
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masterThesis -
88
Intratumoral FoxP3<sup>+</sup>Helios<sup>+</sup> Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
منشور في 2017"…In this preliminary study, we report that the majority of CD3<sup>+</sup> T cells in the TME are CD4<sup>+</sup> T cells with high co-expression of programmed death 1 (PD-1)/cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and PD-1/CD39 molecules. Levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs were significantly increased in the TME. …"
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89
Cerebrospinal α‐Synuclein Oligomers Reflect Disease Motor Severity in DeNoPa Longitudinal Cohort
منشور في 2023"…CSF oligomeric-α-synuclein levels appear to increase with diseases severity and reflect PD motor rather than cognitive trajectories. © 2021 The Authors. …"
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90
Enhancing eggplant (Solanum melongena L.) yield and water use efficiency through optimized irrigation and nitrogen practices in open field conditions
منشور في 2024"…While average fruit weight did not differ significantly across nitrogen levels, the highest fruit yield was recorded under F1 and F2 treatments. …"
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91
Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line
منشور في 2020"…This was associated with an alteration in the expression levels of inflammatory factors in addition to an increase in the expression of the ER stress protein markers, namely immunoglobulin-binding protein (BiP), C/EBP homologous protein (CHOP), activation transcription factor 4 (ATF4), and X-box binding protein (XBP1). …"
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92
Hyperthyroidism‐Induced Nondiabetic Ketoacidosis: A Rare Case Report
منشور في 2025"…<p dir="ltr">Hyperthyroidism, marked by excess thyroid hormones (T4 and T3), presents with symptoms like palpitations, heat intolerance, anxiety, and weight loss despite a normal or increased appetite. Diagnosis involves low serum TSH levels and elevated free T4 and/or T3. …"
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93
Exploring beyond numeric weight loss: The metabolic effects of semaglutide
منشور في 2025"…Semaglutide also slowed weight regain and promoted weight loss after failed <u>bariatric surgery.</u> It also significantly reduced ad libitum <u>energy intake</u>, decreased hunger, and increased satiety in multiple trials. …"
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94
Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care
منشور في 2025"…However, it did not reach statistical significance. 75% of patients with VTE had low anti-Xa levels, while 20% of those with bleeding had high anti-Xa levels.…"
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95
Beyond the needle: How nonsurgical management transforms foot and ankle ability in male footballers with posterior ankle impingement- a longitudinal study
منشور في 2024"…Tenderness and ROM showed significant changes after 4 and 8 weeks. The FAAM% score significantly increased (p < 0.001) after 8 weeks, reflecting enhanced overall functional ability. …"
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96
Modulation of Human Valve Interstitial Cell Phenotype and Function Using a Fibroblast Growth Factor 2 Formulation
منشور في 2015"…Aspect ratio and size were both significantly higher in DMEM (p<0.01). The level of expression of α-SMA was significantly reduced in fibroblast media at day 2 after isolation (p<0.01) and the expression of α-SMA, SM22 and EDA-fibronectin was significantly reduced in fibroblast media at days 7 and 12 post-isolation (p<0.01). …"
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97
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98
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"
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99
Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
منشور في 2014"…Results: The prevalence of T2DM significantly increased with increasing BMI (p < 0.0001). …"
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100
Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity
منشور في 2022"…Functional enrichment analysis revealed long-chain polyunsaturated fatty acids (n-3 and n-6) as the pathway exhibiting the most significant changes with increased disease severity in hypertensive patients (FDR = 0.07).…"