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20001
Table 2_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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20002
Data Sheet 1_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.xlsx
Published 2025“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”
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20003
Table 11_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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20004
Table 1_Brown adipocyte exosome - derived C22:6 inhibits the IL-1β signaling pathway to alleviate rheumatoid arthritis.docx
Published 2025“…Introduction<p>Rheumatoid arthritis (RA) is an autoimmune disorder characterized by significant disability and teratogenic effects, for which there are few effective curative therapies. …”
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20005
Data Sheet 5_CD44 knockdown alters miRNA expression and their target genes in colon cancer.zip
Published 2025“…Introduction<p>Metastasis formation poses a significant challenge to oncologists, as it severely limits the survival of colorectal cancer (CRC) patients. …”
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20006
Table 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..docx
Published 2025“…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …”
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20007
Table 7_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx
Published 2025“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”
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20008
Table 1_An alternative structured weight management protocol to rapid weight loss in mixed martial arts: a prospective interventional study of pre-competition weight management str...
Published 2025“…Starting 7 days before the weigh-in, athletes consumed 7 liters of fluids per day, with intake gradually decreasing. On the day before the weigh-in, they consumed only 0.5 liters. …”
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20009
Image 1_Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly.png
Published 2025“…No covariates significantly influenced this association (p > 0.05).…”
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20010
Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx
Published 2025“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”
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20011
Yeast strains used in this study.
Published 2025“…Furthermore, as H2A.Z mutants only display significant growth defects in genotoxic stress conditions, a more substantive role for H2A.Z in gene expression may only be uncovered after exposure to cellular stress. …”
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20012
Renal Tubule-Specific Angiotensinogen Deletion Attenuates SGLT2 Expression and Ameliorates Diabetic Kidney Disease in Murine Models of Type 1 Diabetes
Published 2025“…Urinary Agt, Angiotensin II (Ang II) and oxidative stress were decreased in <a href="" target="_blank">Akita RT-<i>Agt</i><sup><em>-/-</em></sup> </a>mice cf. …”
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20013
Table 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx
Published 2024“…</p>Results<p>Bioinformatics analysis revealed significant underexpression of LAMP1 in ccRCC (P<0.001), which correlated with poorer prognosis. …”
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20014
Data Sheet 1_Rutin ameliorates LPS-induced acute lung injury in mice by inhibiting the cGAS-STING-NLRP3 signaling pathway.docx
Published 2025“…Rutin administration significantly alleviated LPS-induced lung injury, reducing oxidative stress, apoptosis, and proinflammatory cytokine levels (IL-6, IL-1β, TNF-α). …”
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20015
Image1_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tiff
Published 2024“…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”
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20016
Data Sheet 1_Case Report: A case of first-line treatment for rare ROS1 fusion mutation lung adenocarcinoma with entrectinib.pdf
Published 2025“…Subsequently, the patient underwent whole-brain radiotherapy. Significant improvements were noted in her headache and insomnia symptoms. …”
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20017
Supplementary file 1_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx
Published 2025“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV<sub>1</sub>), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”
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20018
Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx
Published 2025“…Cognitive impairment was a significant predictor of non-motor symptoms in their top three tiers [odds ratio [OR]: 3.88 (95% CI: 1.647 to 9.169)]. …”
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20019
Data Sheet 1_Reduced hemolytic complement activity in the classical pathway (CH50) is a risk factor for poor clinical outcomes of patients with infections: a retrospective analysis...
Published 2025“…</p>Results<p>Of 2,726 patients who met the inclusion criteria, logistic regression models demonstrated that decreased CH50 is a significant predictor of 180-day mortality (OR: 0.98-0.99). …”
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20020
Pathogenicity and transmissibility differences in goose-originated subgenotype 3 duck Tembusu virus in goose embryos and 3-day-old goslings
Published 2024“…In the autumn of 2022, an outbreak of an infectious disease resembling DTMUV was reported in Guangdong Province, China, which caused significantly high mortality in goose embryos, and decreased egg production. …”