Supplementary file 2_Exploring dupilumab for asthma: from mechanistic insights to clinical outcomes, safety, and cost-effectiveness.docx by Omar Z. Ameer (8900039)

“…Clinical trials have demonstrated significant reductions in asthma exacerbation rates, improvements in forced expiratory volume in one second (FEV₁), and decreased oral corticosteroid (OCS) dependence in adults and children with moderate-to-severe asthma. …”

Supplementary file 1_Bioinformatics analysis combined with experimental validation reveals the novel mechanisms of multi-targets of dapagliflozin attenuating diabetic liver injury.... by Pengyu Wang (6680312)

“…Dapagliflozin, a sodium-glucose co-transporter 2 (SGLT2) inhibitor, has shown significant therapeutic benefits in clinical trials for the management of diabetes However, the specific mechanism on the treatment of diabetic liver injury with dapagliflozin is not fully understood. …”

Image 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.png by Li Cui (37567)

“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”

Data Sheet 1_Sex differences in burnout and work-family conflict among Chinese emergency nurses: a cross-sectional study.docx by Dongmei Diao (447916)

“…Multiple linear regression analyses indicated that three dimensions of burnout including emotional exhaustion, depersonalization, and reduced work accomplishment significantly affected work–family role behavior conflict in both sexes. …”

Data Sheet 2_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf by Christina Stevens (9737867)

“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”

Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Table1_Endovascular treatment of aortic coarctation using covered balloon-expandable stents—a systematic review and meta-analysis.pdf by Fei He (145896)

“…The estimated pooled procedural success rate was 100% [95% confidence interval (CI): 98%–100%, I2 = 0, P = 0.78]. Significant decreases in trans-coarctation PGs and SBP were observed. …”

A review of geological characteristics and selenium enrichment in Se-bearing volcanogenic massive sulfide deposits by Wei Zhang (405)

“…<p>Volcanogenic massive sulphide (VMS) deposits consist of upper stratabound massive-to-semimassive sulphide lenses and discordant stringer sulphides in the footwall, hosting significant base metals like Zn, Cu, and Pb, with some enriched in precious (Ag, Au) and semi-metals (like Se and Te). …”

Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif by Khushbu Priya (11863559)

“…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”

Image2_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif by Khushbu Priya (11863559)

“…Background<p>Systemic Lupus Erythematosus (SLE) is characterized by dysregulated immune responses, with neutrophil extracellular traps (NETs) playing a significant role. NETs are recognized by autoantibodies in SLE patients, exacerbating pathology. …”

Supplementary Material for: Primary Vitreoretinal Lymphomas: A Diagnostic Challenge. Report of two recent cases with retinal biopsies and molecular investigations in Halifax, Nova... by figshare admin karger (2628495)

“…She had a further decline in her right eye vision with significant extension of the necrotizing retinitis into the macula and optic disc. …”

Table 5_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx by Wenjun Wang (314231)

“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”

Data Sheet 1_Blue and red LEDs modulate polyphenol production in Precoce and Tardiva cultivars of Cichorium intybus L..pdf by Felicia Menicucci (7495508)

“…The polyphenolic composition of the two cultivars significantly changed depending on the type of LEDs used. …”

Data Sheet 6_Factors influencing, and associated with, physical activity patterns in dogs with osteoarthritis-associated pain.pdf by Christina Stevens (9737867)

“…</p>Results<p>At times of peak activity within a 24-h period, dogs with hindlimb OA pain, higher age, higher Clinical Metrology Instrument scores, higher joint pain, greater Body Condition Score and greater muscle atrophy all had decreased activity profiles. However, only age, hindlimb joint pain, and hindlimb muscle atrophy had statistically significant effects on physical activity.…”

Patient disposition. by Vatsala Rajendram (20691806)

“…Widespread use of the measles vaccine has decreased measles antibody potency in the United States plasma supply. …”

Supplementary file 1_Integrating Drosophila and Vibrio fischeri models for toxicity evaluation: uncovering detoxification trends in psoralea Fructus-TCM formulations.docx by Cheng Zhang (70708)

“…Enzyme assays indicated a decreasing toxicity trend for ESP and SSP compared to PF, with significant changes observed in female flies. …”

Data Sheet 1_Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning.zip by Shuxian Pan (8868356)

“…Based on machine learning-selected indicators, antiviral therapy and The HBV DNA copy number showed a significant correlation with both the occurrence and severity of irAEs. …”

Analysis of potential targets of 20S-protopanaxadiol on diabetic nephropathy based on network pharmacology, molecular docking, and experimental validation by Chenfei Li (5921768)

“…Furthermore, PPD decreased the expression of TGF-β1, p-Smad3, and Smad4 in high glucose-induced HK-2 cells. …”

Table 1_Comparative effectiveness of various combined interventions for type 2 diabetes and obesity: a systematic review and network meta-analysis.docx by Li Cui (37567)

“…ART showed the most significant improvements in BMI, IL-6, and TNF-α levels. …”

Table 12_Identification and validation for biomarkers associated with mitochondrial metabolism in chronic obstructive pulmonary disease.xlsx by Wenjun Wang (314231)

“…The mRNA and protein expression of APRT and LCAT were significantly decreased in COPD patients’ lung tissues.…”