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يعرض 1 - 20 نتائج من 322 نتيجة بحث عن '(( significantly large decrease ) OR ( significantly high disease ))', وقت الاستعلام: 0.10s تنقيح النتائج
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    Revisiting high-density lipoprotein cholesterol in cardiovascular disease: Is too much of a good thing always a good thing? حسب Mohammad Al Zein (20090700)

    منشور في 2024
    "…Despite the correlation between low high-density lipoprotein cholesterol (HDLC) and heightened CVD risk, HDL-raising therapies have yet to showcase significant clinical benefits. …"
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    Tumor-Infiltrating Lymphoid Cells in Colorectal Cancer Patients with Varying Disease Stages and Microsatellite Instability-High/Stable Tumors حسب Salman M. Toor (8854751)

    منشور في 2021
    "…We investigated the expression of immune checkpoints (ICs) on lymphoid populations within the CRC TME and compared with cells from normal colon tissues using samples from 50 patients with varying disease stages. We found that the levels of B cells, T cells, and NK cells were similar, IC-expressing CD4+ and CD4+CD8+ double positive T cells were higher, while CD8+ T cells and CD4−CD8− double negative T cells were significantly lower in CRC tumors. …"
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    A clustering metaheuristic for large orienteering problems حسب Almiqdad Elzein (13141038)

    منشور في 2022
    "…The metaheuristic aims to dramatically improve the computation time of a given Orienteering Problem algorithm without a significant decrease in the solution quality of that algorithm, especially for large Orienteering Problems. …"
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    Association of coronary artery disease and chronic kidney disease in Lebanese population حسب Milane, Aline

    منشور في 2015
    "…This correlation remained highly significant despite considerable inter-patient variability and was at its highest at the most advanced stages of both diseases. …"
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    Disease-Associated α-Synuclein Aggregates as Biomarkers of Parkinson Disease Clinical Stage حسب Nour Majbour (3528548)

    منشور في 2022
    "…<h3>Background and Objectives</h3><p dir="ltr">Robust biomarkers that can mirror Parkinson disease (PD) are of great significance. In this study, we present a novel approach to investigate disease-associated α-synuclein (αSyn) aggregates as biomarkers of PD clinical stage.…"
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    Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans حسب Mahmoud Izadi (12899508)

    منشور في 2024
    "…Our result demonstrates that exposing C. elegans to a high tryptophan dosage leads to DNA damage checkpoint activation and a significant increase in the tryptophan metabolites. …"
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    Stemming cardiovascular diseases in Qatar حسب Nature Research (16552612)

    منشور في 2015
    "…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.…"
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    A GRASP Approach for Solving Large-Scale Electric Bus Scheduling Problems حسب Raka Jovanovic (17947838)

    منشور في 2021
    "…The results of the conducted computational experiments indicate that an increase in infrastructure investment through high speed chargers can significantly decrease the size of the necessary fleets. …"
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    Aortic stiffness, kidney disease, and renal transplantation حسب Bahous, Sola Aoun

    منشور في 2009
    "…In subjects with chronic kidney disease (CKD), treatment of high systolic blood pressure is a key element in preventing disease progression and the occurrence of cardiovascular (CV) events. …"
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    Parkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes حسب Kalyani B. Karunakaran (12478431)

    منشور في 2024
    "…<p dir="ltr">Genome-wide association studies suggest significant overlaps in Parkinson’s disease (PD) and schizophrenia (SZ) risks, but the underlying mechanisms remain elusive. …"
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    Olodaterol for the treatment of chronic obstructive pulmonary disease حسب Ramadan, Wijdan H.

    منشور في 2016
    "…Olodaterol (Striverdi Respimat, Boehringer Ingelheim), a LABA with high selectivity for β2-adrenergic receptors, is indicated for the treatment of chronic obstructive pulmonary disease (COPD); the recommended dose is 5 µg, to be delivered once daily via the Respimat inhaler. …"
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    Minor Intron Splicing from Basic Science to Disease حسب Ettaib El Marabti (23276158)

    منشور في 2021
    "…Consequently, uncovering how mi-INTs splicing is regulated in a tissue-specific manner would allow for better understanding of disease pathogenesis and pave the way for novel therapies, which we highlight in this review.…"
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    Association between dental diseases and history of stroke in the United States حسب Hatem A. Alhadainy (14153157)

    منشور في 2023
    "…Multiple logistic regression modeling was used to estimate the effect of these dental diseases on the self-reported history of stroke with intent to adjust for the other potential determinants: age, sex, race, marital status, health insurance, education, exercise, body mass index, smoking, alcohol, hypertension, high serum cholesterol, and diabetes.…"
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    Allergic rhinitis: Disease characteristics and coping measures in Saudi Arabia حسب Almehizia, Abdulmohsin A.

    منشور في 2019
    "…Background Despite allergic rhinitis (AR) being a highly prevalent disease, according to literature, it is often underdiagnosed or undertreated. …"
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    Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 حسب Gregory A. Roth (6302315)

    منشور في 2020
    "…<p>Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. …"
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