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19381
Table2_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease...
Published 2024“…Despite global declines in IHD incidence over the last three decades, decreasing trends in incidence have slowed and, in some countries, flattened. …”
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19382
The relationship between early-onset preeclampsia and the prognostic nutritional index and inflammatory markers
Published 2024“…The prognostic nutritional index (PNI) was significantly lower in the early-onset preeclampsia group than in the normotensive group (p < 0,001). …”
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19383
Video 2_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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19384
Data Sheet 1_Microbiota profiling from biopsied tissues in complex infections: a diagnostic and prognostic analysis through metagenomic next-generation sequencing.docx
Published 2025“…Early mNGS sampling within 7 days after admission was associated with a significantly decreased risk of all-cause mortality (HR 0.18, 95% CI 0.04–0.94; P=0.04), treatment failure (OR 0.17, 95% CI 0.05–0.66; P=0.01), and increased probability of clinical resolution (OR 3.03, 95% CI 1.24–7.40; P=0.01).…”
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19385
Table 1_Study on Chaiyuwendan decoction’s inhibition of hippocampal neuron apoptosis to alleviating depression by activating the AKT/CREB pathway.docx
Published 2025“…Chaiyuwendan decoction (CYWD) has significant clinical efficacy in treating depression, however, its specific mechanism is still unclear. …”
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19386
Video 5_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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19387
Image 2_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff
Published 2025“…Healthy control also showed globally increased [<sup>18</sup>F]SMBT-1 uptake. There was no significant correlation between the degree of [<sup>18</sup>F]FDOPA uptake and [<sup>18</sup>F]SMBT-1 uptake in any brain region.…”
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19388
Image 4_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff
Published 2025“…Healthy control also showed globally increased [<sup>18</sup>F]SMBT-1 uptake. There was no significant correlation between the degree of [<sup>18</sup>F]FDOPA uptake and [<sup>18</sup>F]SMBT-1 uptake in any brain region.…”
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19389
Table 1_Structural and functional alterations in the contralateral hemisphere following pediatric intracranial surgery: a pilot longitudinal neuroimaging study.docx
Published 2025“…Recent therapeutic advances have significantly improved survival rates, necessitating increased attention to post-operative cognitive outcomes, which are crucial determinants of patients’ quality of life.…”
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19390
Data Sheet 1_2D speckle-tracking echocardiography assessment of left atrial and left ventricular mechanics: outcomes in patients with atrial fibrillation treated with hybrid ablati...
Published 2025“…At follow-up, LAEDV decreased from baseline [44.7 mL vs 53.8 mL, P = 0.025]. …”
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19391
Video 1_Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.mp4
Published 2025“…These metabolic and signalling alterations were associated with decreased tumour proliferation and increased MHC-I surface expression.…”
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19392
Image 2_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif
Published 2025“…We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …”
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19393
Image 2_Analysis and contrast of psoriasis disease burden trends in China and globally from 1990 to 2021.tif
Published 2025“…The AAPC of the ASIR, ASPR, and ASDR in China was 0.7434%, 0.8765%, and 0.8827%, respectively, significantly outpacing the global AAPC of 0.2204%, 0.2220%, and 0.2426%, respectively. …”
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19394
Table 1_Assessing the disease burden of lower respiratory infections attributable to particulate matter pollution: trends from 1990 to 2021 and projections for 2022-2050.xlsx
Published 2025“…Children under 5 years of age group still accounted for the most PMP-related deaths, with the number decreasing from 851,458 (95% UI: 211,026 to 1,363,810) in 1990 to 201,078 (95% UI:61,817 to 337,232). …”
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19395
Data Sheet 1_Overexpression of KPC contributes to ceftazidime-avibactam heteroresistance in clinical isolates of carbapenem-resistant Klebsiella pneumoniae.docx
Published 2024“…Silencing bla<sub>KPC</sub> expression significantly decreased the CZA MIC in resistant subpopulations with high bla<sub>KPC</sub> expression and hindered the emergence of CZA heteroresistance in their parental strains. …”
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19396
Data Sheet 1_Temperature extremes across elevation gradients: evidence from two German mountain observatories.pdf
Published 2025“…Temperature extremes have also changed markedly: cold extremes have declined significantly at both locations (e.g., the duration of cold spells has decreased by 16 days at Hohenpeißenberg and by 10 days at Zugspitze, over the period 1981–2024), while warm extremes exhibit a pronounced rise, especially in the Warm Spell Duration Index (WSDI), which has nearly doubled since the 1980s. …”
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19397
Table 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.docx
Published 2025“…Healthy control also showed globally increased [<sup>18</sup>F]SMBT-1 uptake. There was no significant correlation between the degree of [<sup>18</sup>F]FDOPA uptake and [<sup>18</sup>F]SMBT-1 uptake in any brain region.…”
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19398
Data Sheet 1_Linarin alleviates colonic barrier dysfunction induced by enterotoxic Escherichia coli in weaned piglets by regulating the gut microbiota and metabolic pathways.docx
Published 2025“…</p>Results<p>Linarin supplementation significantly ameliorated colonic crypt hyperplasia, increased goblet cell numbers, and decreased diarrhea incidence following ETEC infusion. …”
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19399
Table1_Global, regional, and national time trends in ischaemic heart disease incidence over three decades (1990–2019): an age-period-cohort analysis of the global burden of disease...
Published 2024“…Despite global declines in IHD incidence over the last three decades, decreasing trends in incidence have slowed and, in some countries, flattened. …”
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19400
The epidemiology and gene mutation characteristics of pyrazinamide-resistant <i>Mycobacterium tuberculosis</i> clinical isolates in Southern China
Published 2025“…These findings indicate that <i>rpsA</i> and <i>panD</i> may not significantly contribute to the development of PZA resistance in clinical <i>M. tuberculosis</i> isolates.…”