Image 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif حسب Chanchan Xiao (9522614)

"…</p>Results<p>Our findings revealed that mutant epitopes in the Omicron variant led to escape from antigen presentation and diminished CD8 T-cell immune responses. We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …"

Data Sheet 1_Campylobacter colonization and undernutrition in infants in rural eastern Ethiopia — a longitudinal community-based birth cohort study.docx حسب Dehao Chen (4966207)

"…We measured anthropometry, surveyed sociodemographic determinants, and collected stool and urine samples. …"

Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx حسب Wenjun Li (41954)

"…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …"

Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf حسب Wenjun Li (41954)

"…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …"

30-year trends in incidence of acute STEMI and NSTEMI in the Belgian Province of Luxembourg. A long-term follow-up of the MONICA-BELLUX registry حسب Bernhard L. Gerber (10171583)

"…</p><p>b) What this study adds</p><p>In a 30-year registry in Luxembourg using modern AMI definitions, overall, AMI incidence decreased significantly, primarily due to a 3.8-fold reduction in STEMI.…"

Ultimate Lateral resistance of Tetrapod Pile Foundation in Rate-dependent and Strain-softening Clay حسب Zi-hao Zhao (21085578)

"…The effect of the reciprocal of soil sensitivity is more significant, while the strain rate <b>exhibits</b> a linear positive interaction with the ultimate lateral resistance. …"

Data Sheet 1_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... حسب Ettore Silvagni (9576002)

"…When assessing the interaction between the period of drug delivery and the treatment with JAKis on the risk of new CVEs, no significant interaction was observed (p = 0.838), while the interaction was statistically significant for baseline CV risk (p = 0.007).…"

Data Sheet 2_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... حسب Ettore Silvagni (9576002)

"…When assessing the interaction between the period of drug delivery and the treatment with JAKis on the risk of new CVEs, no significant interaction was observed (p = 0.838), while the interaction was statistically significant for baseline CV risk (p = 0.007).…"

Table 1_A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism.docx حسب Grace E. Shryack (21596426)

"…</p>Results<p>Progressing gestation in both CD and GDM dams significantly decreased protein and mRNA markers of hepatic mitochondrial biogenesis (Pgc1-α, Tfam), autophagy (Atg5, Sqstm1), mitophagy (Pink1, Bnip3) and lipid handling (Ampk, pAMPK/AMPK, FAS, ACC, pACC, Mttp) with a main effect for time (P<0.05). …"

Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... حسب Xuan Chen (158617)

"…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …"

Table 6_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx حسب Zemin Liu (224306)

"…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …"

Table 3_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx حسب Songqin Chen (9625886)

"…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…"

Table 2_Sodium nitroprusside improves circulatory failure in rabbit acute pulmonary embolism combined with shock model possibly by enhancing NO release and inhibiting TLR4/NF-кB/HI... حسب Yuchan Zhou (10928151)

"…Pulmonary angiography showed that the mean pulmonary artery pressure increased significantly and the mean arterial pressure decreased significantly in the model group, which could be reversed by SNP treatment. …"

Table_3_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.DOCX حسب Ling Li (38566)

"…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …"

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx حسب Yingchao Wu (2870927)

"…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…"

Table 7_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx حسب Zemin Liu (224306)

"…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …"

Data_Sheet_1_miR-124 Alleviates Ischemic Stroke-Induced Neuronal Death by Targeting DAPK1 in Mice.docx حسب Yan Shi (166398)

"…</p>Results<p>In vivo and in vitro results demonstrated that levels of miR-124 were significantly decreased following stroke, whereas changes in death-associated protein kinase 1 (DAPK1) levels exhibited the converse pattern. …"

Supplementary Material for: How the COVID-19 Pandemic Impacted Neurological Hospital Admissions in Germany - A Retrospective Analysis حسب figshare admin karger (2628495)

"…While overall admissions decreased, average case severity was significantly higher. …"

Table 5_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx حسب Zemin Liu (224306)

"…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …"

Data Sheet 4_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.pdf حسب Yingchao Wu (2870927)

"…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…"