Image 2_PLK1 inhibition impairs erythroid differentiation.jpeg by Peijun Jia (11334594)

“…Although PLK1 inhibitors have emerged as promising therapeutic agents for cancer, their use has been linked to significant anemia in a subset of patients, yet the underlying mechanisms remain poorly understood. …”

Image 1_PLK1 inhibition impairs erythroid differentiation.jpeg by Peijun Jia (11334594)

“…Although PLK1 inhibitors have emerged as promising therapeutic agents for cancer, their use has been linked to significant anemia in a subset of patients, yet the underlying mechanisms remain poorly understood. …”

Discovering a novel dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) inhibitor and its impact on tau phosphorylation and amyloid-β formation by Huang-Ju Tu (630766)

“…Its dysregulation is linked to neurodegenerative disorders like Down syndrome and Alzheimer’s disease. …”

Supplementary Material for: Aberrant Inflammatory Cells of Peripheral Blood in Nasal Inverted Papilloma by figshare admin karger (2628495)

“…Finally, M%L%R level was significantly increased in both Grade-I and Grade-II patients (all p < 0.05). …”

Supplementary Material for: Healing Diabetic Foot Ulcers with Topical Timolol Improves Healed Epithelial Integrity by figshare admin karger (2628495)

“…Results: Transepidermal water loss at 1-, 2- and 3-months post-healing was significantly lower in the timolol group than in the placebo group (p<0.01). …”

Using Penalized Synthetic Controls on Truncated Data: A Case Study on Effect of Marijuana Legalization on Direct Payments to Physicians by Opioid Manufacturers by Bikram Karmakar (6494186)

“…Our analysis finds a significant decrease in direct payments from opioid manufacturers to pain medicine physicians as an effect of MML passage. …”

Supplementary file 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.pd... by Bei Li (90587)

“…</p>Conclusion<p>While there has been a general decrease in the global burden of childhood otitis media linked to secondhand smoke exposure. …”

Table 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.docx by Bei Li (90587)

“…</p>Conclusion<p>While there has been a general decrease in the global burden of childhood otitis media linked to secondhand smoke exposure. …”

Supplementary file 1_Association between the difference in cystatin C and creatinine-based eGFR and risks of multiple cardiovascular diseases: a prospective cohort study.docx by Zhiyu Qiao (12514712)

“…</p>Results<p>During a mean follow-up of 13.1 years, the positive eGFR_diff group exhibited significantly lower mortality, cardiovascular disease (CVD) incidence, and the occurrence of CVD-related conditions. …”

Table 1_Longitudinal changes in vitamin D during twin pregnancy: association with maternal–neonatal outcomes.docx by Zhentong Dai (22629206)

“…The RCS revealed an L-shaped VD-sPTB risk relationship. Each 1 ng/mL VD decrease increased sPTB risk by 14.94% (OR = 0.87). …”

The effect of the supernatants of <i>E</i>. <i>coli</i> 25922 in different conditions on MRSA and MSSA and their self-production of EDF. by Shahriar Bakhti (20391188)

“…In all the analyses, p<0.05 was considered statistically significant. The data were expressed as the mean value plus–minus the standard error of the mean (mean ± SEM).…”

Table 3_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…A substantial correlation was found by multivariate Cox proportional hazards analysis between increased PRR and a lower risk of in-hospital and ICU mortality. Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Table 1_Emergency department utilization among youth in foster care: benefits of a patient-centered medical home.pdf by Nicholas Szoko (11260475)

“…Compared to before the PCMH, ED utilization was significantly lower during engagement with the PCMH [IRR: 0.62 (95% CI: 0.54–0.70)]. …”

Data Sheet 1_A new strategy improving TB diagnosis: stratified urine LAM test based on lymphocyte counts.docx by Hongzhi Li (271473)

“…For patients with lymphocyte counts <0.8 × 10⁹/L, the cost of AIMLAM was further reduced to $67.84 (a 47.74% decrease), which was lower than GeneXpert ($111.65) and sputum culture ($94.28).…”

Table 1_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…A substantial correlation was found by multivariate Cox proportional hazards analysis between increased PRR and a lower risk of in-hospital and ICU mortality. Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Supplementary Material for: Phoxilium® as a Phosphate-Sparing Solution for Continuous Renal Replacement Therapy in Paracetamol-Induced Acute Liver Failure by figshare admin karger (2628495)

“…Phoxilium® patients experienced a small but significant decrease in median arterial pH and standard base excess, which remained within normal limits, but lower than with Accusol® (p = 0.018 and p = 0.046, respectively). …”

Table 2_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…A substantial correlation was found by multivariate Cox proportional hazards analysis between increased PRR and a lower risk of in-hospital and ICU mortality. Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Table 1_Enhancement of oxaliplatin efficacy and amelioration of intestinal epithelial damage by Lactobacillus rhamnosus GG through modulation of gut microbiota.xlsx by Zijie Zhang (2543533)

“…Specifically, the Oxp group exhibited a decrease in Clostridium_XlVa and an increase in Desulfovibrio, indicating a shift in microbial balance. …”

Protein levels of Bcl-2 family markers in limbal stromal cells (LSCs) and in Aniridia-LSCs (AN-LSCs), after treatment with 0 µM, 50 µM and 75 µM Cobalt chloride (CoCl₂),... by Shanhe Liu (5251313)

“…<p>Data represent mean±SD from three independent experiments. Two-way ANOVA followed by Dunnett’s test was used, significant p values are indicated. …”

Table 1_Relationship between plasma atherogenic index and subclinical hypothyroidism: an analysis of NHANES data and animal experiment.docx by Qiwei Chen (1417807)

“…Animal experiments confirmed that compared with the CG, rats in the MG exhibited significantly higher levels of blood lipid, AIP and TSH, but lower levels of FT4 and FT3.…”