Data Sheet 1_FTO rs9939609 and rs17817449 polymorphisms contribute to metabolic syndrome risk by increasing triglyceride and glucose levels.docx by Yongyan Song (4415074)

“…Similarly, rs17817449 G allele was linked to elevated triglycerides, reduced HDL-C, higher FBG, and increased systolic blood pressure (all P < 0.05). …”

Table1_Effect of inflammatory cytokines and plasma metabolome on OSA: a bidirectional two- sample Mendelian randomization study and mediation analysis.pdf by Xin Sun (127355)

“…</p>Conclusions<p>In this study, we uncovered a novel biomarker and identified two previously unknown metabolites strongly linked to OSA. These findings underscore the potential significance of inflammatory factors and metabolites in the genetic underpinnings of OSA development and prognosis.…”

Image 1_STZ-induced hyperglycemia differentially influences mitochondrial distribution and morphology in the habenulointerpeduncular circuit.tiff by Mohammad Jodeiri Farshbaf (20466956)

“…Introduction<p>Diabetes is a metabolic disorder of glucose homeostasis that is a significant risk factor for neurodegenerative diseases, such as Alzheimer’s disease, as well as mood disorders, which often precede neurodegenerative conditions. …”

PRISMA flow chart of study selection. by Tong-jie Yang (20939652)

“…</p><p> Conclusion </p><p>(1) HU can effectively contribute to the evaluation of bone and soft tissue densities in the proximal femur, and reflect local stress changes. (2) In ONFH patients, bone density does not decrease in the necrotic area of the femoral head before collapse. …”

Table2_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.xlsx by Friederike Behler-Janbeck (3384488)

“…Recently, it has been shown that bone turnover decreases shortly after food consumption. This process has been linked to the fermentation of non-digestible food ingredients such as inulin by gut microbes, which results in the production of the short-chain fatty acids (SCFAs) acetate, propionate and butyrate. …”

Table2_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.xlsx by Friederike Behler-Janbeck (3384488)

“…Recently, it has been shown that bone turnover decreases shortly after food consumption. This process has been linked to the fermentation of non-digestible food ingredients such as inulin by gut microbes, which results in the production of the short-chain fatty acids (SCFAs) acetate, propionate and butyrate. …”

Table 1_The mechanism of Guanxin Qiwei dropping pills target Dubosiella to improve atherosclerosis.docx by Yuanhong Liao (359147)

“…The correlation analysis further demonstrated a significant positive correlation between Dubosiella and the aforementioned metabolites.…”

Table 1_Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome.docx by Mohamed A. Abdelnaim (16976001)

“…Introduction<p>Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain and altered bowel habits, affecting around 11% of individuals globally. It is linked to dysregulation of the brain-gut axis, with altered activity and connectivity in various brain regions. …”

DataSheet1_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.pdf by Friederike Behler-Janbeck (3384488)

“…Recently, it has been shown that bone turnover decreases shortly after food consumption. This process has been linked to the fermentation of non-digestible food ingredients such as inulin by gut microbes, which results in the production of the short-chain fatty acids (SCFAs) acetate, propionate and butyrate. …”

DataSheet1_The short-chain fatty acid receptors Gpr41/43 regulate bone mass by promoting adipogenic differentiation of mesenchymal stem cells.pdf by Friederike Behler-Janbeck (3384488)

“…Recently, it has been shown that bone turnover decreases shortly after food consumption. This process has been linked to the fermentation of non-digestible food ingredients such as inulin by gut microbes, which results in the production of the short-chain fatty acids (SCFAs) acetate, propionate and butyrate. …”

Supplementary file 1_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Single-factor comparison, multiple linear regression and logistic regression implied that gender, age, hypertension level, height, dietary habit, physical-exercise duration, physical-exercise history, and smoking history could be closely linked with cognitive decline. We also observed significant differences in height, physical exercise duration, physical-exercise years, and smoking years between the male and female of the participants. …”

Table 1_The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and pulmonary function: evidence from NHANES 2007–2012.docx by Miaoyan Liu (11943570)

“…</p>Results<p>The results manifested a significant correlation between decreased FEV1 and FVC values and elevated NHHR, most notably within the highest quartile of NHHR (Q4), where the association was most pronounced. …”

Supplementary file 4_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Single-factor comparison, multiple linear regression and logistic regression implied that gender, age, hypertension level, height, dietary habit, physical-exercise duration, physical-exercise history, and smoking history could be closely linked with cognitive decline. We also observed significant differences in height, physical exercise duration, physical-exercise years, and smoking years between the male and female of the participants. …”

Supplementary file 5_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Single-factor comparison, multiple linear regression and logistic regression implied that gender, age, hypertension level, height, dietary habit, physical-exercise duration, physical-exercise history, and smoking history could be closely linked with cognitive decline. We also observed significant differences in height, physical exercise duration, physical-exercise years, and smoking years between the male and female of the participants. …”

Supplementary file 3_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Single-factor comparison, multiple linear regression and logistic regression implied that gender, age, hypertension level, height, dietary habit, physical-exercise duration, physical-exercise history, and smoking history could be closely linked with cognitive decline. We also observed significant differences in height, physical exercise duration, physical-exercise years, and smoking years between the male and female of the participants. …”

Supplementary file 2_Protective and risk factors in daily life associated with cognitive decline of older adults.docx by Fang Tong (484200)

“…Single-factor comparison, multiple linear regression and logistic regression implied that gender, age, hypertension level, height, dietary habit, physical-exercise duration, physical-exercise history, and smoking history could be closely linked with cognitive decline. We also observed significant differences in height, physical exercise duration, physical-exercise years, and smoking years between the male and female of the participants. …”

Table 2_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Table 1_Multi-omics identification and validation of oxidative phosphorylation–related hub genes in schizophrenia.docx by Yu Zhou (89766)

“…Extending these findings in vivo, MK-801–treated mice exhibited behavioral and neuronal deficits, reduced ATP5A fluorescence intensity, and decreased ATP concentrations; expression of all four hub genes was significantly altered, with three (MALAT1, PPIL3, and ITM2A) concordant with transcriptomic results. …”

Data Sheet 2_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Table 1_Comparative transcriptomic and molecular biology analyses to explore potential immune responses to Vibrio parahaemolyticus challenge in Eriocheir sinensis.docx by Duanduan Chen (6860495)

“…<p>Vibrio parahaemolyticus is a significant pathogen affecting shrimp and crab farming, particularly strains carrying genes associated with acute hepatopancreatic necrosis syndrome. …”