Search alternatives:
significantly longer » significantly lower (Expand Search), significantly larger (Expand Search), significantly shorter (Expand Search)
longer decrease » larger decrease (Expand Search), linear decrease (Expand Search), largest decrease (Expand Search)
decrease ros » increased ros (Expand Search), decreased mor (Expand Search), decrease rice (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
significantly longer » significantly lower (Expand Search), significantly larger (Expand Search), significantly shorter (Expand Search)
longer decrease » larger decrease (Expand Search), linear decrease (Expand Search), largest decrease (Expand Search)
decrease ros » increased ros (Expand Search), decreased mor (Expand Search), decrease rice (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
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An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals
Published 2019“…<div><p>Findings</p><p>Here, we demonstrate that OP2113 (5-(4-Methoxyphenyl)-3H-1,2-dithiole-3-thione, CAS 532-11-6), synthesized and used as a drug since 1696, does not act as an unspecific antioxidant molecule (i.e., as a radical scavenger) but unexpectedly decreases mitochondrial reactive oxygen species (ROS/H<sub>2</sub>O<sub>2</sub>) production by acting as a specific inhibitor of ROS production at the I<sub>Q</sub> site of complex I of the mitochondrial respiratory chain. …”
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Time-varying effect of anti-coagulation regime on sub-distribution hazards for all-cause mortality.
Published 2022Subjects: -
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Unadjusted cumulative incidence of stroke and all-cause mortality by type of anti-coagulant.
Published 2022Subjects: -
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