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Phosphorylation as an Effective Tool to Improve Stability and Reduce Toxicity of Antimicrobial Peptides
Published 2024“…Among them, W<sub>3</sub>BipY<sub>8</sub>-P stood out as the most promising peptide, exhibiting similar antibacterial activity as its unphosphorylated analog W<sub>3</sub>BipY<sub>8</sub> but with significantly reduced hemolytic activity (19-fold decrease), cytotoxicity (3.3-fold decrease), and an extended serum half-life 6.3 times longer than W<sub>3</sub>BipY<sub>8</sub>. …”
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Average days to heal a wound in 2022 and 2023.
Published 2025“…</p><p>Results</p><p>Average healing time for all wounds decreased significantly from 62.5 days in 2022 to 38.6 days in 2023, a 38.2% improvement (p < 0.001). …”
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CONSORT flow diagram.
Published 2024“…The interventions had statistically significant effects only on decreasing the prevalence of overweight and obesity. …”
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Recruitment flow diagram of the current study.
Published 2025“…In phase 2, EQ-5D-5L summary improved most in participants with higher education levels and longer recovery expectations; EQ-VAS improved most in cyclists and patients with longer recovery expectations.…”
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Table2_Significant nocturnal wakefulness after sleep onset in metabolic dysfunction–associated steatotic liver disease.DOCX
Published 2024“…HC 8.5 vs. 5.5, p = 0.0036), longer wakefulness after sleep onset (MASLD vs. HC 45.4 min vs. 21.3 min, p = 0.0004), and decreased sleep efficiency (MASLD vs. …”
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Table1_Significant nocturnal wakefulness after sleep onset in metabolic dysfunction–associated steatotic liver disease.DOCX
Published 2024“…HC 8.5 vs. 5.5, p = 0.0036), longer wakefulness after sleep onset (MASLD vs. HC 45.4 min vs. 21.3 min, p = 0.0004), and decreased sleep efficiency (MASLD vs. …”
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DataSheet1_Significant nocturnal wakefulness after sleep onset in metabolic dysfunction–associated steatotic liver disease.PDF
Published 2024“…HC 8.5 vs. 5.5, p = 0.0036), longer wakefulness after sleep onset (MASLD vs. HC 45.4 min vs. 21.3 min, p = 0.0004), and decreased sleep efficiency (MASLD vs. …”
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DataSheet3_Significant nocturnal wakefulness after sleep onset in metabolic dysfunction–associated steatotic liver disease.PDF
Published 2024“…HC 8.5 vs. 5.5, p = 0.0036), longer wakefulness after sleep onset (MASLD vs. HC 45.4 min vs. 21.3 min, p = 0.0004), and decreased sleep efficiency (MASLD vs. …”
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DataSheet2_Significant nocturnal wakefulness after sleep onset in metabolic dysfunction–associated steatotic liver disease.PDF
Published 2024“…HC 8.5 vs. 5.5, p = 0.0036), longer wakefulness after sleep onset (MASLD vs. HC 45.4 min vs. 21.3 min, p = 0.0004), and decreased sleep efficiency (MASLD vs. …”
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DataSheet4_Significant nocturnal wakefulness after sleep onset in metabolic dysfunction–associated steatotic liver disease.PDF
Published 2024“…HC 8.5 vs. 5.5, p = 0.0036), longer wakefulness after sleep onset (MASLD vs. HC 45.4 min vs. 21.3 min, p = 0.0004), and decreased sleep efficiency (MASLD vs. …”
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GRADE judgements.
Published 2025“…The study results demonstrated that physical exercise combined with conventional rehabilitation significantly improved VO<sub>2Peak</sub> (MD = 4.91, 95% CI: 3.52–6.29, P < 0.001), 6MWT (MD = 37.11, 95% CI: 11.72–62.51, P = 0.004), FVC% (MD = 6.54, 95% CI: 4.9–8.17, P < 0.001), and FEV<sub>1</sub>% (MD = 8.27, 95% CI: 7.39–9.14, P < 0.001) in burn patients compared to conventional rehabilitation. …”
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Basic characteristics of the included studies.
Published 2025“…The study results demonstrated that physical exercise combined with conventional rehabilitation significantly improved VO<sub>2Peak</sub> (MD = 4.91, 95% CI: 3.52–6.29, P < 0.001), 6MWT (MD = 37.11, 95% CI: 11.72–62.51, P = 0.004), FVC% (MD = 6.54, 95% CI: 4.9–8.17, P < 0.001), and FEV<sub>1</sub>% (MD = 8.27, 95% CI: 7.39–9.14, P < 0.001) in burn patients compared to conventional rehabilitation. …”
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The data of meta-analysis.
Published 2025“…The study results demonstrated that physical exercise combined with conventional rehabilitation significantly improved VO<sub>2Peak</sub> (MD = 4.91, 95% CI: 3.52–6.29, P < 0.001), 6MWT (MD = 37.11, 95% CI: 11.72–62.51, P = 0.004), FVC% (MD = 6.54, 95% CI: 4.9–8.17, P < 0.001), and FEV<sub>1</sub>% (MD = 8.27, 95% CI: 7.39–9.14, P < 0.001) in burn patients compared to conventional rehabilitation. …”
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Risk of bias.
Published 2025“…The study results demonstrated that physical exercise combined with conventional rehabilitation significantly improved VO<sub>2Peak</sub> (MD = 4.91, 95% CI: 3.52–6.29, P < 0.001), 6MWT (MD = 37.11, 95% CI: 11.72–62.51, P = 0.004), FVC% (MD = 6.54, 95% CI: 4.9–8.17, P < 0.001), and FEV<sub>1</sub>% (MD = 8.27, 95% CI: 7.39–9.14, P < 0.001) in burn patients compared to conventional rehabilitation. …”
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Overall risk of bias assessment.
Published 2025“…The study results demonstrated that physical exercise combined with conventional rehabilitation significantly improved VO<sub>2Peak</sub> (MD = 4.91, 95% CI: 3.52–6.29, P < 0.001), 6MWT (MD = 37.11, 95% CI: 11.72–62.51, P = 0.004), FVC% (MD = 6.54, 95% CI: 4.9–8.17, P < 0.001), and FEV<sub>1</sub>% (MD = 8.27, 95% CI: 7.39–9.14, P < 0.001) in burn patients compared to conventional rehabilitation. …”
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Funnel plot of VO<sub>2Peak</sub> inclusion studies.
Published 2025“…The study results demonstrated that physical exercise combined with conventional rehabilitation significantly improved VO<sub>2Peak</sub> (MD = 4.91, 95% CI: 3.52–6.29, P < 0.001), 6MWT (MD = 37.11, 95% CI: 11.72–62.51, P = 0.004), FVC% (MD = 6.54, 95% CI: 4.9–8.17, P < 0.001), and FEV<sub>1</sub>% (MD = 8.27, 95% CI: 7.39–9.14, P < 0.001) in burn patients compared to conventional rehabilitation. …”
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Analysis of subgroups.
Published 2025“…The study results demonstrated that physical exercise combined with conventional rehabilitation significantly improved VO<sub>2Peak</sub> (MD = 4.91, 95% CI: 3.52–6.29, P < 0.001), 6MWT (MD = 37.11, 95% CI: 11.72–62.51, P = 0.004), FVC% (MD = 6.54, 95% CI: 4.9–8.17, P < 0.001), and FEV<sub>1</sub>% (MD = 8.27, 95% CI: 7.39–9.14, P < 0.001) in burn patients compared to conventional rehabilitation. …”
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Grid division diagram.
Published 2025“…When the height is 2.5m and above, the windbreak efficiency is greater than 90%, and the windbreak effect is significantly improved. (2) The change of sand barrier height has a significant effect on the windbreak efficiency between the second and third sand barriers. (3) Among the three sand-blocking fences, when the height of the sand-blocking fence is 2.5m, the thickness of the sand is 50.51% and 58.33% higher than that of the 2m high sand-blocking fence, and the sand-blocking effect is the most significant. …”