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significantly lower » significantly higher (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
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6101
Data Sheet 1_Synergistic effect of regorafenib with aminoglycosides in ferroptosis-mediated liver injury.docx
Published 2025“…</p>Conclusion<p>Thus, combination therapy of regorafenib with amikacin and gentamycin causes significant elevation of iron and lipid peroxidation levels and alteration in protein expressions, which mediates ferroptotic cell death and leads to liver injury.…”
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6102
Data Sheet 1_Distinct gut microbiota and metabolomic profiles in HBV-related liver cirrhosis: insights into disease progression.pdf
Published 2025“…</p>Conclusions<p>HBV-LC patients displayed significant alterations in gut microbiota and fecal metabolites, which correlated closely with disease severity and inflammatory status. …”
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6103
DataSheet1_CircFOXO3 upregulation mediates the radioresistance of glioblastoma by affecting cellular metabolome.DOCX
Published 2024“…Metabolic alterations are known to contribute to radioresistance by activating antioxidant responses and promoting DNA repair. …”
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6104
Table1_CircFOXO3 upregulation mediates the radioresistance of glioblastoma by affecting cellular metabolome.XLSX
Published 2024“…Metabolic alterations are known to contribute to radioresistance by activating antioxidant responses and promoting DNA repair. …”
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6105
Supplementary file 1_Multimodal MRI study of gray matter and functional connectivity abnormalities in adolescents with bipolar disorder.docx
Published 2025“…VBM analysis demonstrated decreased GMV in the left cerebellum. No significant correlations were found between imaging measures and clinical scale ratings.…”
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6106
Image 1_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Furthermore, our investigation unearthed profound alterations in the immune and glial cell populations within the CNS. …”
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6107
Image 4_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Furthermore, our investigation unearthed profound alterations in the immune and glial cell populations within the CNS. …”
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6108
Image 3_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Furthermore, our investigation unearthed profound alterations in the immune and glial cell populations within the CNS. …”
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6109
Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff
Published 2025“…Furthermore, our investigation unearthed profound alterations in the immune and glial cell populations within the CNS. …”
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6110
Image 2_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
Published 2025“…Furthermore, our investigation unearthed profound alterations in the immune and glial cell populations within the CNS. …”
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6111
Data Sheet 1_PM2.5 exposure reprograms cell cycle dynamics in uterine immune cells at single-cell resolution.docx
Published 2025“…Cell cycle analysis demonstrated cell type-specific responses to PM2.5 exposure: macrophages showed increased G1 phase representation (53.45%, +7.37%) with decreased G2M phase cells (18.97%, -12.79%), while NK cells exhibited relatively modest cell cycle alterations (G1: 28.6%, +2.5%; G2M: 45.1%, +2.6%; S: 26.4%, -5.1%). …”
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6112
Image 2_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb...
Published 2024“…Sequencing analysis revealed significant alterations in the microbiota composition at both the phylum and genus levels during phage therapy. …”
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6113
Image 1_Phage therapy for extensively drug resistant Acinetobacter baumannii infection: case report and in vivo evaluation of the distribution of phage and the impact on gut microb...
Published 2024“…Sequencing analysis revealed significant alterations in the microbiota composition at both the phylum and genus levels during phage therapy. …”
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6114
Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025
Published 2025“…Transient insulin receptor blockade also altered the liver's molecular clock, particularly affecting PPARα transcriptional responsiveness.…”
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6115
S1_Figure.pdf
Published 2025“…We observed no age-associated changes in coupling efficiency (ADP:O) of mitochondrial reticulum preparations, but respiratory control (RCR) was decreased in older mice. Additionally, older skeletal muscle exhibited subtle yet significant reductions in the expression of proteins functionally related to substrate uptake and oxidation (mMCT1, mPC1, CPT1b, HADH). …”
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6116
Heterogeneity dynamics: influencing rock type responses to overburden pressure, Permian–Triassic of the Persian Gulf
Published 2025“…Findings showed limestone’s frequent rock type changes under reservoir pressure <i>via</i> the Winland method, while dolomite samples showed significant alterations using the flow zone indicator method. …”
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6117
Table 1_Deep brain stimulation for obsessive compulsive disorder leads to symptom changes of comorbid irritable bowel syndrome.docx
Published 2025“…Introduction<p>Irritable bowel syndrome (IBS) is a common condition characterized by abdominal pain and altered bowel habits, affecting around 11% of individuals globally. …”
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6118
Table 7_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
Published 2025“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”
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6119
Table 1_The impact of Helicobacter pylori infection and eradication therapies on gut microbiota: a systematic review of microbial dysbiosis and its implications in gastric carcinog...
Published 2025“…H. pylori infection resulted in significant alterations in gut and gastric microbiota, with a notable increase in inflammation-associated bacteria, such as Proteobacteria and Streptococcus. …”
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6120
Table 1_Changes in white matter microstructure in the brain of patients with inflammatory bowel disease are associated with abdominal pain.docx
Published 2025“…</p>Conclusions<p>In patients with inflammatory bowel disease, particularly those with Crohn’s disease, alterations in the white matter microstructure that are primarily involved in pain processing have been observed.…”