يعرض 101 - 120 نتائج من 258 نتيجة بحث عن '(( significantly lower decrease ) OR ( significantly mediate decrease ))~', وقت الاستعلام: 0.47s تنقيح النتائج
  1. 101

    Data Sheet 1_Association of the dietary index for gut microbiota with sleep disorder among US adults: the mediation effect of dietary inflammation index.docx حسب Yingying Li (50341)

    منشور في 2025
    "…A higher DI-GM score is associated with a lower incidence of sleep disorders, while the DII significantly mediated the relationship between DI-GM and sleep disorders. …"
  2. 102
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  4. 104

    Table 1_Linking the Planetary Health Diet Index to sarcopenia: the mediating effect of the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (N... حسب Huan Chen (6545)

    منشور في 2025
    "…Analysis of the dose–response curve suggested a linear relationship between PHDI and sarcopenia. Furthermore, a significant positive association was identified between NHHR and sarcopenia [OR = 1.09, 95% CI: 1.03, 1.16], with NHHR found to decrease as PHDI increased [beta coefficient (β) = −0.09, 95% CI: −0.11, −0.06]. …"
  5. 105

    Table 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.docx حسب Kexin Xu (757891)

    منشور في 2025
    "…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…"
  6. 106

    Image 1_CD3zeta-mediated modulation of TCR signaling: a novel strategy for neuroprotection in retinal ganglion cell degeneration.jpeg حسب Kexin Xu (757891)

    منشور في 2025
    "…The neuroprotective effect of CD3ζ knockdown was accompanied by the restoration of MAPK signaling, specifically the phosphorylation of ERK and p38, and attenuation of NF-κB activation, indicated by decreased p65 phosphorylation. Furthermore, CD3ζ knockdown reduced the levels of proinflammatory mediators (IL-1β, TNF-α, and MMP-9) and increased that of the anti-inflammatory cytokine IL-10, creating a retinal microenvironment conducive to neuroprotection.…"
  7. 107
  8. 108

    Supplementary file 1_The mediating role of Body Roundness Index in the association between Life’s Crucial 9 and infertility: a cross-sectional study using NHANES 2013–2018.docx حسب Ying Wang (11406)

    منشور في 2025
    "…</p>Conclusion<p>There is a significant negative correlation between LC9 and infertility, with BRI playing a partial mediating role. …"
  9. 109

    Table 1_Association between Life’s Crucial 9 and metabolic dysfunction-associated steatotic liver disease: the mediating role of neutrophil-percentage-to-albumin ratio.docx حسب Na Zhu (331131)

    منشور في 2025
    "…</p>Conclusion<p>Good CVH status (high LC9 score) was associated with lower prevalence of MASLD and liver fibrosis, and NPAR partially mediated the association between LC9 and MASLD. …"
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  11. 111

    <i>Salmonella </i>Typhimurium <i>StiP</i>-mediated upregulation of membrane protein Alx drives complement evasion via CFI-dependent C3b degradation حسب jin guan (21792620)

    منشور في 2025
    "…We further explored the role of <i>StiP</i> in host blood environment adaptation and found that 263<i>ΔStiP</i> displayed 3.12-fold reduced HeLa cell adhesion, 3.74-fold lower HeLa cell invasion, 1.92-fold decreased intra-macrophage survival, and 50% reduced serum resistance versus wild-type 263 (WT263), collectively indicating that <i>StiP</i> is critical for host blood environment adaptation in invasive <i>S</i>. …"
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    Presentation1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance fo... حسب Holger Neb (13018218)

    منشور في 2025
    "…Among increased lipids, the remarkable changes in 1-AG, 2-AG, and to a lower extent of 6-keto-PGF<sub>1-alpha</sub> plasma levels showed a certain agreement with inflammatory phases. …"
  14. 114

    Presentation1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance fo... حسب Holger Neb (13018218)

    منشور في 2025
    "…Among increased lipids, the remarkable changes in 1-AG, 2-AG, and to a lower extent of 6-keto-PGF<sub>1-alpha</sub> plasma levels showed a certain agreement with inflammatory phases. …"
  15. 115
  16. 116

    DataSheet1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for s... حسب Holger Neb (13018218)

    منشور في 2025
    "…Among increased lipids, the remarkable changes in 1-AG, 2-AG, and to a lower extent of 6-keto-PGF<sub>1-alpha</sub> plasma levels showed a certain agreement with inflammatory phases. …"
  17. 117

    DataSheet1_Analysis of fatty acid-derived lipids in critically ill patients after cardiac surgery yields novel pathophysiologically relevant mediators with possible relevance for s... حسب Holger Neb (13018218)

    منشور في 2025
    "…Among increased lipids, the remarkable changes in 1-AG, 2-AG, and to a lower extent of 6-keto-PGF<sub>1-alpha</sub> plasma levels showed a certain agreement with inflammatory phases. …"
  18. 118

    Data Sheet 1_The mediating role of body surface area-adjusted basal metabolic rate: effects of low muscle mass and central obesity on cognitive impairment in Chinese patients with... حسب Ya-Jie Zhai (20609765)

    منشور في 2025
    "…Mediation analysis suggested that BMR/BSA played a significant mediating role in WC, ASM and FFM on CI risk, with a mediation proportion ranging from 45.73% to 50.87%.…"
  19. 119

    Image 4_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg حسب Xiao Li (107004)

    منشور في 2024
    "…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …"
  20. 120

    Image 2_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg حسب Xiao Li (107004)

    منشور في 2024
    "…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …"