بدائل البحث:
significantly mediate » significantly mediated (توسيع البحث), significantly predicted (توسيع البحث), significantly mitigated (توسيع البحث)
mediate decrease » mediated defense (توسيع البحث)
teer decrease » greater decrease (توسيع البحث)
significantly mediate » significantly mediated (توسيع البحث), significantly predicted (توسيع البحث), significantly mitigated (توسيع البحث)
mediate decrease » mediated defense (توسيع البحث)
teer decrease » greater decrease (توسيع البحث)
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
منشور في 2025"…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…"
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Eggs jointly coordinate a caspase-1 and caspase-8 dependent pyroptotic cell death.
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related to Fig 4. ROS, K+ efflux and cathepsin B do not affect TNFα production in response to eggs.
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ROS, K<sup>+</sup> efflux and cathepsin B are required for NLRP3 activation.
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The loss of NLRP3 and AIM2 results in reduced Th17 and enhanced Th2 cytokine responses.
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Egg-induced IL-1β and IL-17 production is dependent on both Caspase-1 and Caspase-8.
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