بدائل البحث:
significantly impaired » significantly impairs (توسيع البحث), significantly improved (توسيع البحث), significantly improve (توسيع البحث)
significantly mediate » significantly mediated (توسيع البحث), significantly predicted (توسيع البحث), significantly mitigated (توسيع البحث)
impaired decrease » marked decrease (توسيع البحث)
mediate decrease » mean decrease (توسيع البحث), mediated defense (توسيع البحث)
significantly impaired » significantly impairs (توسيع البحث), significantly improved (توسيع البحث), significantly improve (توسيع البحث)
significantly mediate » significantly mediated (توسيع البحث), significantly predicted (توسيع البحث), significantly mitigated (توسيع البحث)
impaired decrease » marked decrease (توسيع البحث)
mediate decrease » mean decrease (توسيع البحث), mediated defense (توسيع البحث)
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2981
Image 1_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
منشور في 2025"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"
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2982
Image 4_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
منشور في 2025"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"
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2983
Image 3_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
منشور في 2025"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"
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2984
Image 5_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tiff
منشور في 2025"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"
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2985
Image 2_Moderate regular physical exercise can help in alleviating the systemic impact of schistosomiasis infection on brain cognitive function.tif
منشور في 2025"…Remarkably, exercise decreased glial cell production of TNFα, suggesting a shift towards a less pro-inflammatory environment. …"
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2986
Data Sheet 1_A dual inhibitor of TrxR1 and XIAP induces pyroptosis in melanoma.docx
منشور في 2025"…Mechanistically, TRI-03 not only increases intracellular reactive oxygen species (ROS) levels by inhibiting TrxR1 activity but also decreases XIAP expression, leading to the activation of the caspase-9/caspase-3/GSDME axis and irreversible GSDME-mediated pyroptosis in melanoma cells. …"
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2987
Table 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati...
منشور في 2025"…Our proteomic analysis revealed AFG3L2 impairment, with significant dysregulation of proteins critical for mitochondrial function, cytoskeletal integrity, and cellular metabolism. …"
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2988
Image 1_Multi-omics-based phenotyping of AFG3L2-mutant lymphoblasts determines key factors of a pathophysiological interplay between mitochondrial vulnerability and neurodegenerati...
منشور في 2025"…Our proteomic analysis revealed AFG3L2 impairment, with significant dysregulation of proteins critical for mitochondrial function, cytoskeletal integrity, and cellular metabolism. …"
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2989
<b><i>N</i></b><sup><strong>6</strong></sup><b>-Methyladenosine demethylase FTO controls</b><b>macrophage homeostasis in diabetic vasculopathy</b>
منشور في 2024"…<p dir="ltr"><b>Abstract</b></p><p dir="ltr">Diabetic vasculopathy, encompassing complications such as diabetic retinopathy, represents a significant source of morbidity, with inflammation playing a pivotal role in the progression of these complications. …"
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2990
Data for the manuscript entitled "The interrelation between family environment, attributional style and aggression related to emotional disorder among children and adolescents"
منشور في 2025"…Most children’s aggressive behavior peaks before age three and then decreases as cognitive abilities and self-control develop. …"
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2991
Table 1_Effect of cholecalciferol on immune and vascular function in non-diabetic chronic kidney disease.docx
منشور في 2025"…A significant increase in mRNA expression of vitamin D-responsive genes (cathelicidin, IL-10, VDR, and CYP27B1) was observed. …"
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2992
Supplementary Material for: Dorsal Column Spinal Cord Stimulation Attenuates Brain-Spine Connectivity through Locomotion and Visuospatial-Specific Area Activation in Progressive Fr...
منشور في 2024"…Introduction: Freezing of gait (FOG) is a clinical phenomenon with major life impairments and significant reduction in quality of life for affected patients. …"
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2993
Table 1_Microplastics in focus: a silent disruptor of liver health- a systematic review.docx
منشور في 2025"…., increased serum cysteine, decreased hepatic cysteine, and disturbed homocysteine metabolism), impair mitochondrial bioenergetics, and lead to significant lipid accumulation after exposures lasting up to 500 h. …"
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2994
Image 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.jpeg
منشور في 2025"…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…"
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2995
Anthropogenic CO2–induced seawater acidification driven the biogeochemical processes of dimethylsulfide in Northwestern Pacific marginal seas
منشور في 2025"…Seawater acidification exerts significant control over marine biogeochemical cycles, including those involving of dimethylsulfide (DMS), a critical climate-regulating sulfur compound. …"
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2996
Table 1_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
منشور في 2025"…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…"
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2997
Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx
منشور في 2024"…Introduction<p>The emergence of the wide variety of novel tigecycline resistance tet(X) variants, including tet(X3), tet(X4), tet(X5), and tet(X6), has raised a serious threat to global public health and posed a significant challenge to the clinical treatment of multidrug-resistant bacterial infections.…"
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2998
Table 2_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
منشور في 2025"…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…"
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2999
Table 3_PCP4 inhibits the progression of prostate cancer through Ca2+/CAMKK2/AMPK/AR pathway.xlsx
منشور في 2025"…A series of molecular and biochemical experiments were carried out in PCa cell lines to investigate the mechanism underlying PCP4-mediated tumor suppression.</p>Results<p>(1) PCP4 gene loss occurs at high frequency in PCa patients, and decreased expression of PCP4 correlates with poor prognosis of PCa, particularly CRPC development; (2) TMPRSS2-ERG fusion frequently co-occurs with PCP4 deletion; (3) PCP4 suppresses prostate cancer progression in vitro and in vivo; (4) PCP4 is an androgen receptor (AR) suppressed gene; (5) PCP4 was involved in the stabilization of CAMKK2 protein; (6) PCP4 inhibits PCa progression by regulating Ca<sup>2+</sup>/CAMKK2/AMPK/AR signaling axis.…"
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3000
Supplemental file for Training alters cytokine and soluble receptor responses
منشور في 2025"…However, in the untrained group, the expression of these soluble receptors either remained unchanged or decreased, suggesting greater cytokine bioavailability. …"