Showing 1 - 20 results of 2,765 for search '(( significantly mediated decrease ) OR ( significant source decrease ))', query time: 0.37s Refine Results
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    Source data file. by Laura Mora-Bitria (20477525)

    Published 2024
    “…We conclude that iKIRs significantly decrease HLA class II protective associations and suggest that iKIRs regulate CD4<sup>+</sup> T cell responses in T1D.…”
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    Source data for Fig 2. by Qi Xu (134661)

    Published 2025
    “…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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    Source data for lung metabolomics. by Qi Xu (134661)

    Published 2025
    “…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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    Source data for Fig 5. by Qi Xu (134661)

    Published 2025
    “…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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    Source data for Fig 1. by Qi Xu (134661)

    Published 2025
    “…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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    Source data for Fig 3. by Qi Xu (134661)

    Published 2025
    “…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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    Source data for Fig 4. by Qi Xu (134661)

    Published 2025
    “…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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