Down-regulation of VANGL2 in IBD patients triggers overt activation of NLRP3 inflammasome. by Huaji Jiang (16907514)

Structure–Activity Relationships of Azaquinazolinone Derivatives as ¹⁸F‑Labeled PET Probes Targeting Ghrelin Receptors by Hiroyuki Watanabe (312793)

Subjects:

pRPS6 and proliferation rates of starved Vasa2+/Piwi1+ cells were independent on the daytime of refeeding, and phospho-RPS6 was found in S- and M-phase Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

Lys823 in NLRP3 is essential for its K27-linked ubiquitination and autophagic degradation. by Huaji Jiang (16907514)

VANGL2 specifically inhibits the activation of NLRP3 inflammasome. by Huaji Jiang (16907514)

Effect of imidacloprid and rutin administration on wet mass, dry mass, and water content of the thorax in Africanized honey bee foragers. by Juan P. Hernández (22216133)

Effect of imidacloprid (Im) and rutin (Ru) administration on evaporation dynamics of extracellular fluid (ECF) extracted from thoraxes of Africanized honey bee foragers. by Juan P. Hernández (22216133)

Effect of imidacloprid (Im) and rutin (Ru) administration on thoracic electrical impedance in Africanized honey bee foragers. by Juan P. Hernández (22216133)

VANGL2 recruits NLRP3 to OPTN for selective autophagic degradation. by Huaji Jiang (16907514)

VANGL2 recruits MARCH8 to promote the K27-linked ubiquitination of NLRP3. by Huaji Jiang (16907514)

Thioflavin-T (ThT) fluorescence analysis of amyloid fibril formation in wild-type and p.R163C mutant αB-crystallin under thermochemical stress. by Aref Baharvand (21713886)

Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents by Marcian E. Van Dort (21374093)

“…Additionally, compound LP-65 demonstrated significant modulation of MEK and mTOR signaling activity in human glioma cells (D54) and human melanoma cells (A375), with a corresponding decrease in cellular proliferation and migration. …”

Study Data. by Jonathan S. Jahr (2709088)

“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”

Study outcomes. by Jonathan S. Jahr (2709088)

“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”

Number of visits per clinic type, 2013-2015. by Jacob Dreiher (14856863)

“…During PE, statistically significant longer waiting times were found for surgery (+1.0 day) and imaging (+1.1 days), while a 2.4 days decrease was noted in pediatrics, controlled for age, sex, ethnicity and the daily number of visits. …”

Patient characteristics. by Jonathan S. Jahr (2709088)

“…It has also been hypothesized that the bradycardia and rare instances of cardiac arrest occurring after the use of sugammadex may be due to a transient decrease in circulating corticosteroids, causing a temporary ‘mini Addisonian crisis.’ …”

Feeding and starvation affect the proportion and cell cycle activity of Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

Changes in the active H3K27ac and repressive H3K27me3 histone marks among Vasa2+/Piwi1+ and all cells in fed, starved, and refed juvenile polyps. by Eudald Pascual-Carreras (12115380)

“…Between fed, T_5ds and T_20ds timepoints, MFI levels of H3K27ac progressively and significantly decreased while levels H3K27me3 (M) did not change significantly (N). …”

The effect of feeding and starvation on the proliferative competence and onset of cell cycle re-entry in all cell cycle-gated cells. by Eudald Pascual-Carreras (12115380)

The TOR inhibitors Rapamycin and AZD-8055 strongly reduce RPS6 phosphorylation and cell proliferation in Vasa2+/Piwi1+ cells. by Eudald Pascual-Carreras (12115380)

“…<i>n</i> = 2–4 biological replicates per condition, with 15 individuals per replicate. Significance levels for Student <i>t</i> test are indicated for adjusted <i>p</i> values: *<i>p</i> < 0.05, ***<i>p</i> < 0.001, ***<i>p</i> < 0.0001. d: day(s), n.s.: non-significant. …”