Modulation of SLFN11 induces changes in DNA Damage response in breast cancer by Christophe Michel Raynaud (17449906)

“…The use of a CRISPR-dCas9 UNISAM and KRAB system could increase or decrease SLFN11 expression significantly (up to fivefold), stably and specifically in BT-549 and T47D cancer cell lines. …”

Phosphorus supplementation recovers the blunted diet-induced thermogenesis of overweight and obese adults by Bassil, Maya S.

“…Overweight/obese subjects had a blunted DIT with placebo, while P supplementation induced a 23% increase in their DIT area under the curve (p < 0.05), which was associated with a significant increase in carbohydrate oxidation. …”
Get full text
Get full text
Get full text
Get full text

Molecular Mechanisms of Adiponectin-Induced Attenuation of Mechanical Stretch-Mediated Vascular Remodeling by Crystal M. Ghantous (14571292)

“…Mechanical stretch significantly increased p-ERK1/2 after 10 minutes, whereas APN significantly reduced stretch-induced ERK1/2 phosphorylation. …”

DNA damage induced by micellar-delivered doxorubicin and ultrasound: comet assay study by Husseini, Ghaleb

“…However, when ultrasound was applied, a rapid and significant increase in DNA damage was observed (P=0.0001). …”
Get full text

Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats by Azar Hosseini (33501)

“…Histopathological studies of the cardiac tissue showed isoprenaline-induced injury that was significantly attenuated by the extract.…”

Peripherally injected cholecystokinin-induced neuronal activation is modified by dietary composition in mice by Zeeni, N.

“…In addition, a significant interaction was found between CCK administration and the HF diet, shown by an increased activation in the PVN, which suggests a decrease the inhibiting action of CCK. …”
Get full text
Get full text
Get full text
Get full text

The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis by Daaboul, Hamid E.

“…Only Cisplatin treatment caused a significant decrease in body weight and increase in serum ALT. …”
Get full text
Get full text
Get full text
Get full text

Sleeping habits during COVID-19 induced confinement: A study from Jordan by Mahmoud A. Alomari (14780446)

“…<p dir="ltr">Sleep can significantly modulate the immune response to infectious agents. …”

Cafeteria diet-fed mice is a pertinent model of obesity-induced organ damage by Zeeni, Nadine

Get full text
Get full text
Get full text
Get full text

IL-1 stimulates ceramide accumulation without inducing apoptosis in intestinal epithelial cells by Homaidan, Fadia R.

“…Neither IL-1 nor ceramide induced apoptosis in IEC, but they increased bcl-2 levels and decreased bax and p21 levels without affecting bcl-x and p53 levels. …”
Get full text
Get full text
Get full text

Kefir induces cell-cycle arrest and apoptosis in HTLV-1-negative malignant T-lymphocytes by Rizk, Sandra

“…Conclusion: In conclusion, kefir is effective in inhibiting proliferation and inducing apoptosis of HTLV-1-negative malignant T-lymphocytes. …”
Get full text
Get full text
Get full text

Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats by Bylan, Diana

“…In addition, a significant decrease in serum creatinine was observed in groups receiving cannabis extract at the doses of 5 and 10 mg/kg. …”
Get full text
Get full text
Get full text

Synthetic Cannabinoid AB-FUBINACA Negatively Impacted the Male Fertility and Induced Testicular Toxicity by Ayman Alzu’bi (13162392)

“…AB-FUBINACA treatment also causes a significant dose related decrease in sperm viability. …”

Therapeutic Effect of Lebanese Cannabis Oil Extract in the Management of Sodium Orthovanadate-Induced Nephrotoxicity in Rats by Habchy, Chistabel

“…All doses of Cannabis oil caused significant decrease in serum urea, as well as in serum creatinine at a dose of 20mg/Kg. …”
Get full text
Get full text
Get full text

Prevention of carcinogen-induced mouse skin papilloma by Daucus carota (wild carrot) aqueous extract by Mroueh, M.

“…Intraperitoneal treatment decreased hyperplasia and dermal infiltration with an increase in the level of hyperkeratosis. …”
Get full text
Get full text
Get full text
Get full text

Arginine Deprivation in AML Cells Induces Ferroptosis, a Type of Autophagy-Mediated Cell Death by Tohme, Sara

“…Overall, these findings provide evidence that arginine deprivation induced by [HuArgI(Co)-PEG5000] leads to increased ROS production, lipid peroxidation, and dysregulation of iron metabolism and antioxidant pathways, all of which are hallmarks for the occurrence of ferroptosis in AML cells following arginine deprivation. …”
Get full text
Get full text
Get full text

The role of twinning and stacking fault-induced plasticity on the mechanical properties of aluminum-lithium-graphene nanocomposites by Sara I. Ahmad (16936923)

Hepatoprotective Effect of Oleuropein-Rich Extract from Olive Leaves against Cadmium-Induced Toxicity in Mice by Hedya Jemai (14571781)

“…Results showed that Cd induced a significant increase in liver injury biomarkers coupled with enhanced lipid peroxidation (MDA) and significant depletion of antioxidants (CAT and SOD). …”

Cucurbita pepo inhibits benign prostatic hyperplasia induced by testosterone in sprague-dawley rats. (c2011) by Nawfal, Tania M.

Get full text
Get full text

Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice by Ayman, Alzu'bi

“…Our results revealed that the administration of AB-FUBINACA induced a significant impairment in recognition memory associated with histopathological changes in the hippocampus. …”
Get full text
Get full text
Get full text