Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation by Shilpa Kuttikrishnan (3520079)

“…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …”

Tryptophanyl-tRNA synthetase-1 (WARS-1) depletion and high tryptophan concentration lead to genomic instability in Caenorhabditis elegans by Mahmoud Izadi (12899508)

“…Our result demonstrates that exposing C. elegans to a high tryptophan dosage leads to DNA damage checkpoint activation and a significant increase in the tryptophan metabolites. …”

Analysis and Design of Circular Shafts Using Finite Element Method by Chehadeh, Ali Saleh

Get full text

Effect of sintering additives on the properties of alumina toughened zirconia (ATZ) by M. K. G. Abbas (18021646)

“…In general, all ATZ samples exhibited a similar trend, as the results showed that the relative density and mechanical properties increased with increasing sintering temperature regardless of the addition of dopants. …”

Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance by Gh Rasool Bhat (13038132)

“…These processes are pivotal in the development and progression of tumors, contributing to the multifaceted nature of cancer and the challenges associated with its treatment. Despite significant advancements in targeted therapies, cancer cell adaptability and subsequent therapy-induced resistance remain persistent obstacles in achieving consistent, successful cancer treatment outcomes. …”

Detecting Mental Stress using EEG and Deep Learning by Badr, Yara

Get full text

Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…The author’s line of argument is that conceptual skills are likely to play a significant role in ambidexterity leadership for innovation. …”
Get full text

Application of the electric resistance tomographic technique to investigate its efficacy in cuttings transport in horizontal drilling scenarios by Muhammad Saad Khan (16724634)

“…Inner pipe rotations also significantly enhanced the cuttings transport by adding induced helical motion and vorticities in the annulus. …”

Water-pipe smoking promotes epithelial–mesenchymal transition and invasion of human breast cancer cells via ERK1/ERK2 pathways by Khaled W. Sadek (14153196)

“…<p>With the increasing popularity of water-pipe smoking (WPS), it is critical to comprehend how WPS may affect women’s health. …”

Introducing a Novel Figure of Merit for Evaluating Stability of Perovskite Solar Cells: Utilizing Long Short-Term Memory Neural Networks by Zahraa Ismail (22457644)

“…The comparative analysis of model complexity confirmed that increasing the sophistication of the LSTM model significantly enhances predictive accuracy and generalization capabilities. …”

Long-Chain Acyl-CoA Synthetase 1 Role in Sepsis and Immunity: Perspectives From a Parallel Review of Public Transcriptome Datasets and of the Literature by Jessica Roelands (7516439)

“…Finally, while ACSL1 expression was induced in blood in vitro by a wide range of pathogen-derived factors as well as TNF, induction of ACSL4 appeared restricted to flagellated bacteria and pathogen-derived TLR5 agonists and IFNG. …”

Synthesis and evaluation of novel Cu-based adsorbent-containing catalysts for CO₂ hydrogenation to methanol and value-added products by Rim Ismail (18192922)

“…Increased Cu content from 10 wt% to 30 wt% with fixed CaO content of 10 wt% resulted in a small increase in CO₂ conversion where the highest CO₂ conversion of 16.44% and the highest methanol selectivity (17.75%) were obtained for catalyst containing 20 wt% of copper. …”

Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department by Atilla Temel (17788481)

“…Thorax ultrasonography is a useful technique with high specificity in diagnosing pneumothorax, but its sensitivity decreases significantly when the size is below 1 cm.…”

High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow i... by Samar, Shurbaji

“…A very strong correlation was also observed between cobas® e 601 serum and Finecare™ serum (r = 0.88; p < 0.0001). …”
Get full text
Get full text
Get full text

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi... by Bogachev, Oleg

“…Moreover, AEBP1 has been shown to promote macrophage inflammatory responsiveness by inducing nuclear factor (NF)-κB activity via IκBα downregulation. …”
Get full text

Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE by SHAREEF, SUNDUS LUAY

“…The research found that a significant variation in building height reduces the cooling load more than a gradual height variation, and consequently offers more energy saving. …”
Get full text

Friction stir extrusion of ultra-thin wall biodegradable magnesium alloy tubes — Microstructure and corrosion response by Vasanth C. Shunmugasamy (10474766)

“…Upon exposure to Hank’s balanced salt solution at 37 ◦C, microgalvanic coupling resulting from the gradient through-the-thickness grain size and texture differences between the tube inner and outer surfaces, and residual strain arising from the FSE process, promoted a localized attack that preferentially initiated on the outer tube surface and progressed inwards. Static recovery induced by a short duration heat treatment at low temperature did not alter the microstructure but promoted a more general corrosion attack with a significantly reduced corrosion rate. …”

One-year experience of hybrid closed-loop system in children and adolescents with type 1 diabetes previously treated with multiple daily injections: drivers to successful outcomes by Goran Petrovski (129836)

“…</p> <h2>Methods</h2> <p>This was a 1-year observational study, as a continuation of the previous 3 months prospective study of pediatric patients with T1D conducted at Sidra Medicine in Qatar. …”

A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle by Sanjay Kumar (8853)

“…By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. It increases the solubility of flavonoids leading to reduced toxicity and higher bioavailability. …”

Anti-xa guided enoxaparin thromboprophylaxis is associated with less thromboembolism than fixed dose dalteparin in trauma patients admitted to intensive care by Ahmad Kloub (16855149)

“…</p><h3>Methods</h3><p dir="ltr">This observational study compared injured patients admitted one year before (pre-P) and after (post-P) implementing a new VTEp protocol. …”