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101
Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma
منشور في 2020"…Drug treatment in these cells significantly reduced cellular proliferation, viability, migration and increased apoptosis. …"
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masterThesis -
102
Alpha lipoic acid attenuates ER stress and improves glucose uptake through DNAJB3 cochaperone
منشور في 2020"…Treatment of C2C12 cells with 0.3 mM of ALA triggers a significant increase in the expression of DNAJB3 mRNA and protein. …"
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103
Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
منشور في 2018"…HFD also significantly increased the number of adipocytes in the bone marrow microenvironment of WT mice as compared to KO mice. …"
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104
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
منشور في 2024"…Interestingly, BTZ treatment induced autophagy, which is evident from the increased expression of microtubule-associated proteins nucleoporin p62 and LC-3A/B. …"
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105
Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury
منشور في 2021"…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …"
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106
Cognitive Vigilance Enhancement using Audio Stimulation of Pure Tone at 250 Hz
منشور في 2021"…The entropy measures show that the temporal profile of the EEG signals has significantly increased with VE. The classification results showed that SVM technique with DE features across all frequency bands can detect VE levels with accuracy varying between (92.10±02.24)% to (98.32±01.14)%, sensitivity of (92.50±02.33)% to (98.66±01.00)%, and specificity of (91.70±02.32)% to (97.99±01.05)%. …"
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article -
107
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108
Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients
منشور في 2018"…Here, we demonstrated for the first time that an increase of reactive oxygen species (ROS) generation induced by sera from IPF patients drives both collagen type I deposition and proliferation of primary human pulmonary artery smooth muscle cells (HPASMCs). …"
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109
Mechanical stretch and prostaglandin E2 modulate critical signaling pathways in mouse podocytes
منشور في 2010"…These results show that cellular signaling in podocytes is significantly altered under diabetic conditions (i.e., hyperglycemia and increased Pgc). …"
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article -
110
Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts
منشور في 2015"…The results reconfirm the well-known observations that minimum film thickness is very little affected by lubricant compressibility while central film thickness decreases linearly with the increase in volume compression of the lubricant. …"
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article -
111
Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Additionally, after β-catenin silencing, OA treatment significantly increased the expression of nuclear transcription factors SREBP-1 and TCF4, whereas Ex-4 significantly decreased this upregulation. …"
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112
Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
منشور في 2019"…Amino acid profiles were unaffected by an acute increase in IR induced by the lipid infusion. IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …"
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113
Breast cancer cells and bone marrow mesenchymal stromal cells
منشور في 2017"…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …"
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114
Modification of glucocorticoid effects on body weight gain, plasma lipids by changes in diet composition
منشور في 2003"…The HC diet induced a statistically significant increase in TG concentration. …"
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article -
115
In vivo assessment of the nephrotoxic effects of the synthetic cannabinoid AB-FUBINACA
منشور في 2024"…<h3>Background</h3><p dir="ltr">The widespread misuse of synthetic cannabinoids (SCs) has led to a notable increase in reported adverse effects, raising significant health concerns. …"
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116
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117
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118
Antibacterial Properties of Polysulfone Membranes Blended with Arabic Gum
منشور في 2019"…Possible mechanisms for the prevention of bacterial colonization were discussed. Significantly, the inhibition of bacterial attachment and growth on PS/AG membranes was observed for both Gram-positive and Gram-negative bacterial models, rendering these novel membranes with strong biofouling resistance attractive for water treatment applications.…"
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119
Comparative outcome analysis of home-initiated non-medical interventions among toddlers with orally ingested substances
منشور في 2015"…In regression: intervention significantly increased length of stay (t = 0.213, adj. …"
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120