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Orofacial Clefts
Published 2021“…We also found an increased RhoA activation in these cells which could be causative of the observed increase in focal adhesions as well as a decreased Cdc42 activation which could further explain the loss in cell polarity. …”
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323
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …”
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324
Evaluation of Lycopus uniflorus water extract for anti-inflammatory, anti-ulcerogenic and antioxidant activities
Published 2009“…The highest inhibition of edema development was achieved at 100mg/kg BW dose and the edema was decreased by 67% compared with diclofenac (60%) at 10mg/kg BW. …”
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325
A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation
Published 2021“…Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). …”
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326
Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
Published 2022“…<p dir="ltr">Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and <u>type</u><u> </u><u>2 diabetes</u> has increased rapidly and has become one of the leading causes of death worldwide. …”
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Visible Light Photocatalytic Activity of Ag/WO<sub>3</sub> Nanoparticles and its Antibacterial Activity Under Ambient Light and in The Dark
Published 2022“…Ultraviolet–visible spectra analysis observed a large redshift in the absorbing band edge and decreased bandgap energy from 2.6 to 2.1 eV. …”
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The clinical characteristics and outcomes of patients with pulmonary hypertension in association with hyperthyroid state: A systematic review
Published 2022“…<h3>Background</h3><p dir="ltr">Pulmonary hypertension (PHTN) may occur in thyroid disorders, especially in hypothyroidism. However, there is increasing evidence of PHTN in hyperthyroidism (HTH). …”
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330
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Similarly, we observed decreased in vivo ectopic bone formation. …”
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Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi...
Published 2011“…Moreover, AEBP1 has been shown to promote macrophage inflammatory responsiveness by inducing nuclear factor (NF)-κB activity via IκBα downregulation. …”
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332
Insulin detemir in combination with oral antidiabetic drugs improves glycemic control in persons with type 2 diabetes in Near East countrie
Published 2017“…The percentage of persons who achieved the target of HbA1c<7% increased from .7% at baseline to 39% at week 24. Mean FPG decreased significantly from 213.7 ± 60.1 mg/dL to 120.3 ± 25.7 mg/dL (P<.001), and mean PPG from 271 ± 65.3 mg/dL to 158.1 ± 36.4 mg/dL (P<.0001). …”
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333
Effect of partial medial meniscectomy on anterior tibial translation in stable knees
Published 2013“…Our values might reflect a temporarily increase of anterior laxity under specific conditions but whether a significant laxity remains in some knees, such changes may lead to higher cartilage loading and early osteoarthritis.…”
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334
Andrographolide potentiates the antitumor effect of topotecan in acute myeloid leukemia cells through an intrinsic apoptotic pathway
Published 2018“…Background Topotecan (TP) is an anticancer drug acting as topoisomerase I inhibitor that is used in the treatment of many types of cancers including leukemia, but it has significant side effects. Andrographolide, a compound extracted from Andrographis paniculata, was recently proven to inhibit the growth of cancer cells and can induce apoptosis. …”
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335
Prevalence of bullying and violence among adolescents in Arab Gulf countries: a systematic review
Published 2025“…Academic impacts included increased absenteeism (24–29%) and decreased performance.</p><h3 dir="ltr">Conclusion</h3><p dir="ltr">This review highlights the widespread prevalence and serious consequences of bullying among adolescents in AGC, with clear gender differences and significant impacts on mental health and academic performance. …”
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Investigation of Groundwater Depletion in the State of Qatar and Its Implication to Energy Water and Food Nexus
Published 2021“…Results show a substantial depletion in the groundwater thickness (0.24 ± 0.20 cm/year) during the period of observation (2002–2020). Long-term temperature data indicates that the annual mean temperature increased significantly by 1.02 °C between 1987 and 2016, while total rainfall exhibited a slight decreasing trend. …”
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COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
Published 2020“…These protein panels target biological processes involved in vessel damage, platelet degranulation, the coagulation cascade and the acute phase response [1], with greater protein changes dependent on the COVID-19 severity. However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …”
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Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…Notable COX-2 inhibitory activities (IC<sub>50</sub> = 0.065–0.24 μM) were observed relative to celecoxib (IC<sub>50</sub> = 0.049 μM). …”
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Effect of Surface Treatment of Halloysite Nanotubes (HNTs) on the Kinetics of Epoxy Resin Cure with Amines
Published 2020“…At high heating rates, a similar behavior but not that significant was observed due to the accelerated gelation in the system. …”
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The anti-neoplastic activity of novel platinum II and IV complexes against A549 lung cancer cells
Published 2021“…Western blots experiments were also carried out to observe the effect of the drugs on key apoptotic proteins. Data revealed a significant drop in procaspase 3 and a significant increase in Bax/Bcl2 ratio, Cytochrome c, Parp and procaspase 8. …”
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masterThesis