Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains حسب Riachi, Naji J.

"…MPTP-induced mortality was not affected, but striatal dopamine depletion was prevented, by MAO inhibition. …"
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A population study of clinically actionable genetic variation affecting drug response from the Middle East حسب Puthen Veettil Jithesh (12040358)

"…On average, Qataris carry 3.6 actionable genotypes/diplotypes, affecting 13 drugs with guidelines for clinical implementation, and 99.5% of the individuals had at least one clinically actionable genotype/diplotype. Increased risk of simvastatin-induced myopathy could be predicted in ~32% of Qataris from the diplotypes of SLCO1B1, which is higher compared to many other populations, while fewer Qataris may need tacrolimus dosage adjustments for achieving immunosuppression based on the CYP3A5 diplotypes compared to other world populations. …"

The antiproliferative and pro-apoptotic effect of kefir on human leukemic cell lines. (c2008) حسب Maalouf, Katia E.

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Environmental enrichment and cafeteria diet synergistically modify the response to chronic variable stress in rats حسب Zeeni, Nadine

"…In addition, there was a significant interaction between diet and EE (P=0.02) on serum CORT levels: the CVS-induced increase in CORT was attenuated in the presence of EE and the CAF diet independently and in a synergistic manner. …"
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Experimental validation of numerical model for thermomechanical performance of material extrusion additive manufacturing process: Effect of infill design & density حسب Ans Al Rashid (14777050)

"…The current practices of the experimental optimization process require significant resources, which can be limited through numerical modeling and simulation techniques. …"

Functional Connectivity Analysis under Vigilance Decrement and Enhanced Mental States حسب Hassanin, Omnia

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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications حسب Sumama Nuthana Kalva (17302906)

"…The results from the compression study showed that increasing magnesium content showed improved mechanical properties, with 15 % WE43 showing the highest strength value of 740.6 MPa and elastic modulus of 6.45 GPa. Also, significant calcium phosphate deposition was observed in the bioactivity study and higher degradation was observed for higher magnesium content scaffolds. …"

Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar حسب Shikha Patel (14151027)

"…Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). Notably, built-up areas and desert lands consistently recorded the highest mean LST in both seasons in all observed years. …"

Waterpipe Tobacco Smoke Nicotine Mediates Resilience to Chronic Stress by Activating BDNF Signaling حسب Khalifeh, Mohamad Rabieh

"…Even though initially, WTS decreased anxiety-like behaviors it was found that prolonged exposure after the completion of CSDS significantly induced anxiety-like behaviors. Finally, we showed that nicotine mediates the effects of WTS only on resilience to stress by increasing BDNF and TRKB levels and signaling. …"
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Effect of chronic and non-chronic moderate wine consumption upon rat lipoprotein profile in the blood. (c2002) حسب Slaiby, Rita

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Chemical characterization and cytotoxic activity evaluation of Lebanese propolis حسب Faour, Wissam H.

"…Toxicity started early after 24 h of incubation and remained till 72 h. Interestingly, the decrease in cell viability was accompanied by a significant increase in p53 protein expression levels and PARP cleavage. …"
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Nonlinear effects in locally resonant nanostrip phononic metasurface at GHz frequencies حسب Feng Gao (3548)

"…Due to the nonlinearity, the resonance frequency of the device decreases with the increase in stimulation power. The underlying mechanism of the nonlinearity is found to be the power-dependent coupling of the adjacent nanostrips. …"

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

"…No differences in macrophage infiltration were apparent throughout primary tumor development, though at 10 weeks a drop in neutrophil infiltrates was observed in Mmp8-wild-type tumors. Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …"

Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties حسب Al Zaabi, Alanood

"…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …"
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An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE حسب ABU-QULBAIN, LANA

"…Outdoor school spaces are significant spaces which, regardless of a child’s residential area, provide great opportunity for outdoor space exploration leading to overall enhancement to the students’ wellbeing. …"
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A cafeteria diet modifies the response to chronic variable stress in rats حسب Zeeni, N.

"…These results show that a highly palatable diet, offering a choice of food items, is associated with a reduction in the response to CVS and could validate a stressor-induced preference for comfort food that in turn could increase body weight.…"
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Transcriptome and Literature Mining Highlight the Differential Expression of ERLIN1 in Immune Cells during Sepsis حسب Susie S. Y. Huang (2824502)

"…In vitro expression of the ERLIN1 gene and proteins was measured by stimulating the whole blood of healthy volunteers to a combination of lipopolysaccharide and peptidoglycan. Septic stimulation induced a significant increase in ERLIN1 expression; however, ERLIN1 was differentially expressed among the immune blood cell subsets. …"

Proteome analysis of Candida albicans cell wall mutants. (c2011) حسب Koussa, Joseph Wissam

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National innovation capacity and the drivers of energy efficiency R&D in the OECD حسب Ashraf Galal Eid (16982736)

"…Contrary to the <u>induced innovation</u> hypothesis, oil price increases consistently depress energy efficiency R&D, suggesting that higher energy costs divert resources from innovation. …"

Outcomes of POCUS‐Guided Peripheral Intravenous Access in Difficult Venous Access Patients: A Systematic Review and Meta‐Analysis حسب Hany A. Zaki (17337673)

"…A systematic review of 15 studies with 1485 patients, sourced from five databases, including PubMed, Cochrane Library, MEDLINE, Web of Science, and Google Scholar, showed POCUS significantly improved success rates (OR: 4.25), first‐attempt success (OR: 5.31), reduced attempts (MD: −0.83), and decreased procedure time (MD: −9.75 min). …"