Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway حسب Kirti.S. Prabhu (17191231)

"…<p dir="ltr">Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options. …"

Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance حسب Gh Rasool Bhat (13038132)

"…These processes are pivotal in the development and progression of tumors, contributing to the multifaceted nature of cancer and the challenges associated with its treatment. Despite significant advancements in targeted therapies, cancer cell adaptability and subsequent therapy-induced resistance remain persistent obstacles in achieving consistent, successful cancer treatment outcomes. …"

Is embolization of segment 4 portal veins before extended right hepatectomy justified? حسب Kishi, Yoji

"…Results After a median of 27 days, the S2+3 volume increased significantly after both RPVE and RPVE+4, but the absolute increase was significantly higher for RPVE+4 (median, 106 mL vs 141 mL; P = .044), as was the hypertrophy rate (median, 26% vs 54%; P = .021). …"
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The chemical analysis of Lebanese olive oil and the influence of oil enriched diet on Plasma Lipid profile in rats. (c2002) حسب Zarikian, Karen Awadis

"…Following ten week low fat verses high fat diet, no significant difference was observed among the various groups in lipid profile, insulin and Apo B 100 & 48 levels. …"
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Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation حسب Shilpa Kuttikrishnan (3520079)

"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"

Application of the electric resistance tomographic technique to investigate its efficacy in cuttings transport in horizontal drilling scenarios حسب Muhammad Saad Khan (16724634)

"…Inner pipe rotations also significantly enhanced the cuttings transport by adding induced helical motion and vorticities in the annulus. …"

Introducing a Novel Figure of Merit for Evaluating Stability of Perovskite Solar Cells: Utilizing Long Short-Term Memory Neural Networks حسب Zahraa Ismail (22457644)

"…The comparative analysis of model complexity confirmed that increasing the sophistication of the LSTM model significantly enhances predictive accuracy and generalization capabilities. …"

Long-Chain Acyl-CoA Synthetase 1 Role in Sepsis and Immunity: Perspectives From a Parallel Review of Public Transcriptome Datasets and of the Literature حسب Jessica Roelands (7516439)

"…Finally, while ACSL1 expression was induced in blood in vitro by a wide range of pathogen-derived factors as well as TNF, induction of ACSL4 appeared restricted to flagellated bacteria and pathogen-derived TLR5 agonists and IFNG. …"

Detecting Mental Stress using EEG and Deep Learning حسب Badr, Yara

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The role of methanolic extract of Quercus infectoria bark in lipemia, glycemia, gastric ulcer and bacterial growth حسب Khouzami, L.

"…After one month of chronic extract (0.5% w/v) intake via drinking water, there was a significant increase in serum HDL-cholesterol level. …"
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Wild carrot pentane-based fractions suppress proliferation of human HaCaT keratinocytes and protect against chemically-induced skin cancer حسب Shebaby, Wassim N.

"…Additionally, F2 fraction treatment caused an up-regulation of the expression of pro-apoptotic (Bax) and down-regulation of the expression of anti-apoptotic (Bcl2) proteins. A decrease in the phosphorylation of AKT and ERK was also observed. …"
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Synthesis and evaluation of novel Cu-based adsorbent-containing catalysts for CO₂ hydrogenation to methanol and value-added products حسب Rim Ismail (18192922)

"…Increased Cu content from 10 wt% to 30 wt% with fixed CaO content of 10 wt% resulted in a small increase in CO₂ conversion where the highest CO₂ conversion of 16.44% and the highest methanol selectivity (17.75%) were obtained for catalyst containing 20 wt% of copper. …"

Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... حسب Mohamed Yassin (4166515)

"…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …"

Exergames versus self-regulated exercises with instruction leaflets to improve adherence during geriatric rehabilitation: a randomized controlled trial حسب Peter Oesch (3572426)

"…Adherence was comparable at day one (38 min. in the EG and 42 min. in the CG) and significantly higher in the CG at day 10 (54 min. in the CG while decreasing to 28 min. in the EG, <i>p</i> = 0.007, ES 0.94, 0.39–0.151). …"

Upgrading co-pyrolysis products from ternary biomass: An investigative study of commercial and locally-made catalysts حسب Sabah Mariyam (14150859)

"…At higher temperatures, secondary decompositions become prominent, leading to increased gas yields and decreased char and liquid oil yields. The introduction of catalysts generally enhances char yields across both temperature regimes. …"

An additive manufacturing approach based on electrohydrodynamic printing to fabricate P3HT:PCBM thin films حسب Zulfikre Esa (19457344)

"…As the annealing temperature and the flow rate were increased, discernible alterations in the PCBM clusters were consequently observed in the blends of the film and the size of the PCBM clusters has decreased by 3% while the distance between them was highly reduced by as much as 82%.…"

Effect of Mg incorporation on the properties of PCL/Mg composites for potential tissue engineering applications حسب Sumama Nuthana Kalva (19206064)

"…However, the elastic modulus decreased by around 50% for the same composition. The thermal study revealed a significant reduction in the degradation temperature from above 400°C for pure PCL to around 300°C for PCL/Mg composite having 15% Mg. …"

Friction stir extrusion of ultra-thin wall biodegradable magnesium alloy tubes — Microstructure and corrosion response حسب Vasanth C. Shunmugasamy (10474766)

"…Upon exposure to Hank’s balanced salt solution at 37 ◦C, microgalvanic coupling resulting from the gradient through-the-thickness grain size and texture differences between the tube inner and outer surfaces, and residual strain arising from the FSE process, promoted a localized attack that preferentially initiated on the outer tube surface and progressed inwards. Static recovery induced by a short duration heat treatment at low temperature did not alter the microstructure but promoted a more general corrosion attack with a significantly reduced corrosion rate. …"

Combined effects of treated domestic wastewater, fly ash, and calcium nitrite toward concrete sustainability حسب Abdelrahman Abushanab (17268940)

"…It was also shown that the addition of FA significantly decreased the chloride permeability of TWW concrete by 55%–71%. …"

Metabolomics analyses reveal the crucial role of ERK in regulating metabolic pathways associated with the proliferation of human cutaneous T‐cell lymphoma cells treated with Glabri... حسب Abdul Q. Khan (14153247)

"…Interestingly, results further show that Glabridin induces PCD in CTCL cells by targeting MAPK signalling pathways, particularly the activation of ERK. …"