Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …"

Cucurbita pepo inhibits benign prostatic hyperplasia induced by testosterone in sprague-dawley rats. (c2011) حسب Nawfal, Tania M.

احصل على النص الكامل
احصل على النص الكامل

Interleukin-35 and Thymoquinone nanoparticle-based intervention for liver protection against paracetamol-induced liver injury in rats حسب Maisa Siddiq Abduh (16381125)

"…Moreover, levels of Capase-3, and cytochrome C were significantly reduced by THYO or IL35, while, levels of Bcl-2 were markedly increased. …"

Physiological and pharmacological stimulation for in vitro maturation of substrate metabolism in human induced pluripotent stem cell-derived cardiomyocytes حسب Colleen A. Lopez (18520071)

"…In EHT, FAO was significantly higher than in monolayer cells or those on static scaffolds and could be further increased by culture with oleate and WY-14643. …"

<i>Haematococcus pluvialis</i> Microalgae Extract Inhibits Proliferation, Invasion, and Induces Apoptosis in Breast Cancer Cells حسب Nouralhuda Alateyah (21363215)

"…Interestingly, apoptosis was mediated by a significant loss of mutant p53 protein, and increased Bax/Bcl2 ratio. …"

Western diet induces mild metabolic impairment and aggravates neuropathology in an experimental mouse model of traumatic brain injury حسب Judith, Nwaiwu

"…Results showed that while WD significantly increased fat percentage and elevated plasma cholesterol, there was no change in blood glucose level or body weight, indicating an early stage of MetS. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Hypoxic Stress Induces Complement-Mediated Lysis of Mesenchymal Stem Cells by Downregulating Factor H and CD59 حسب Ramada R. Khaswaneh (22224544)

Oral Spirulina Platensis Attenuates Hyperglycemia and Exhibits Antinociceptive Effect in Streptozotocin-Induced Diabetic Neuropathy Rat Model حسب Mohamed M Abdel-Daim (20362725)

"…To assess the antinociceptive effect of oral Spirulina platensis (SP) powder on formalin-induced nociceptive responses in STZ-induced diabetic rats.…"

Neosetophomone B induces apoptosis in multiple myeloma cells via targeting of AKT/SKP2 signaling pathway حسب Shilpa Kuttikrishnan (3520079)

"…Overall, our findings demonstrated that NSP‐B induces caspase‐dependent apoptosis, increases cell damage, and suppresses MM cell proliferation while improving the cytotoxic impact of BTZ. …"

Alterations in blood Lipoprotein & Apolipoprotein B profile induced by moderate acute & chronic alcohol intake in the rat model. (c2002) حسب Berberi, Rania

"…This latter finding, in addition to the observed modest increase in HDL cholesterol, suggests a cardioprotective effect induced by chronic moderate alcohol consumption.…"
احصل على النص الكامل
احصل على النص الكامل

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase حسب Amira Othman (380131)

Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line حسب Toutounji, Mohamad

"…DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Ultrasound-induced doxorubicin release from folate-targeted and non-targeted P105 micelles: a modeling study حسب Martins, Ana M.

احصل على النص الكامل

Gasoline fume inhalation induces apoptosis, inflammation, and favors Th2 polarization in C57BL/6 mice حسب Nour-Eldine, Wared

"…Static gasoline exposure induced a significant increase (+21%) in lungs/body weight (BW) ratio in GE versus control (CON) mice along with a pulmonary inflammation attested by histological staining. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

A jojoba (Simmondsia chinensis) seed cake extracts express hepatoprotective activity against paracetamol-induced toxicity in rats حسب Firas Feki (17545638)

"…After enzyme treatment, simmondsin content decreased from 33.0 % to 3.0 % and glucose content increased from 16.2 % to 27.3 % reflecting simmondsin hydrolysis. …"

A genome-wide transcriptomic analysis of embryos fathered by obese males in a murine model of diet-induced obesity حسب Laura Bernhardt (14152842)

"…Furthermore, we could show a significant increase in expression of both Gata6 and Samd4b during differentiation of stromal vascular cells into mature adipocytes. …"

High phosphorus diet mitigates impairments in lipid and glucose metabolism associated with diet-induced obesity in male sprague dawley rats حسب Bassil, Maya

"…High fat induced obesity significantly (p<0.05) increased serum cholesterol, triglycerides and ALP in HF group (46.1±3.9mg/dl, 38.8±4.4mg/dl and 192.8±55.9U/l, respectively) compared to control (19.8±2.7mg/dl, 26.0.1±3.7mg/dl and 76.6±7.3U/l, respectively) but P supplementation in HFHP prevented this increase. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways حسب Ibraheem M. Attafi (14151735)

"…Treatment of rats with Pb for three consecutive days significantly increased the accumulation of Pb in lung tissues causing severe interstitial inflammation. …"

Resveratrol Inhibits Oxidative Stress and Prevents Mitochondrial Damage Induced by Zinc Oxide Nanoparticles in Zebrafish (<em>Danio rerio</em>) حسب Roberta Giordo (299595)

"…NP-induced vascular structural abnormalities during embryonic fish development were significantly counteracted by resveratrol treatment. …"

An evaluation of sorter induced cell stress (SICS) on peripheral blood mononuclear cells (PBMCs) after different sort conditions - Are your sorted cells getting SICS? حسب Gerald Pfister (17075275)

"…Recently, the flow cytometry community has become increasingly aware about the potential negative effects this could have on sorted cells and the term “sorter induced cell stress” (SICS) has been proposed. …"