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β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
Published 2017“…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …”
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Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma
Published 2020“…However, only in lower dose of sumac were significant decreases in the expression of oncogenic miR210 and increase of tumor-suppressive miR145 (miR21, miR22, and miR155 were not changed) observed. …”
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87
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…ResultsShade analysis revealed that, in the short term, HP treatment significantly increased lightness and Hue and decreased chroma compared to DW (p < 0.05); however, 1 week after treatment some of the initial gains in tooth lightness were partially lost. …”
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88
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
Published 2019“…Moreover, an overexpression of histone acetylation enzymes was observed in tumorspheres suggesting the active involvement of histone modifications in EMT-induced PD-L1 expression. …”
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The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…</p><h3>Results</h3><p dir="ltr">Shade analysis revealed that, in the short term, HP treatment significantly increased lightness and Hue and decreased chroma compared to DW (<i>p </i>< 0.05); however, 1 week after treatment some of the initial gains in tooth lightness were partially lost. …”
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Colloid retention and mobilization mechanisms under different physicochemical conditions in porous media: A micromodel study
Published 2021“…However, for hydrophobic colloids, changes in solution chemistry significantly increase colloid retention where the colloid interaction become attractive with the increase in ionic strength and decrease in pH values. …”
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Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon
Published 2011“…Increasing the dose to 500 mg/kg body weight caused a significant decrease in stool water content. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…Mice treatment (IP) with HC caused a significant decrease in tumor incidence and size. Similar effects were observed with cisplatin treatment. …”
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The Protective Effects of Daucus carota L. ssp. carota and Cannabis sativa L. Extracts against Cisplatin Induced Nephrotoxicity in Animal Models
Published 2021“…All used doses of COE showed significant decrease in serum urea; however, a significant decrease in serum creatinine was observed only at 20 mg/kg COE. …”
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94
A lipidomic screen of hyperglycemia-treated HRECs links 12/15-Lipoxygenase to microvascular dysfunction during diabetic retinopathy via NADPH oxidase
Published 2015“…In the presence of arachidonic acid, additional eicosanoids generated by 12/15-LOX, including 12- and 11-HETEs, were significantly increased. Fluorescein angiography and retinal albumin leakage showed a significant decrease in retinal hyperpermeability in streptozotocin-induced diabetic mice lacking 12/15-LOX compared with diabetic WT mice. …”
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Fourier Transform Infrared Imaging—A Novel Approach to Monitor Bio Molecular Changes in Subacute Mild Traumatic Brain Injury
Published 2021“…Significant decrease in methyl content and a significant increase in olefinic content were observed in Co and CC regions of mTBI rat brain tissues. …”
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Investigating the Therapeutic Effects of Small Molecule Imipridones In Pediatric Neuroblastoma
Published 2020“…Drug treatment in these cells significantly reduced cellular proliferation, viability, migration and increased apoptosis. …”
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98
Nox2 Activity Is Required in Obesity-Mediated Alteration of Bone Remodeling
Published 2018“…HFD also significantly increased the number of adipocytes in the bone marrow microenvironment of WT mice as compared to KO mice. …”
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Cognitive Vigilance Enhancement using Audio Stimulation of Pure Tone at 250 Hz
Published 2021“…The entropy measures show that the temporal profile of the EEG signals has significantly increased with VE. The classification results showed that SVM technique with DE features across all frequency bands can detect VE levels with accuracy varying between (92.10±02.24)% to (98.32±01.14)%, sensitivity of (92.50±02.33)% to (98.66±01.00)%, and specificity of (91.70±02.32)% to (97.99±01.05)%. …”
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Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
Published 2024“…Interestingly, BTZ treatment induced autophagy, which is evident from the increased expression of microtubule-associated proteins nucleoporin p62 and LC-3A/B. …”
