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181
Bortezomib exerts its anti-cancer activity through the regulation of Skp2/p53 axis in non-melanoma skin cancer cells and C. elegans
Published 2024“…Interestingly, BTZ treatment induced autophagy, which is evident from the increased expression of microtubule-associated proteins nucleoporin p62 and LC-3A/B. …”
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182
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…No differences in macrophage infiltration were apparent throughout primary tumor development, though at 10 weeks a drop in neutrophil infiltrates was observed in Mmp8-wild-type tumors. Using quantitative real-time RT-PCR, we tracked the expression of the entire Mmp and Timp gene families, observing a significant decrease in Mmp3 expression in Mmp8-null tumors compared to wild-type and heterozygotes throughout the time course of the model, which was confirmed at the protein level. …”
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183
Effects of the addition of a high energy density fuel, adamantane to diesel on its cetane number, sooting propensity, and soot nanostructural properties
Published 2022“…The addition of up to 6.75 wt% of adamantane in diesel significantly increased the smoke point of diesel from 18 to 29 mm (and threshold sooting index decreased by 44%), indicating a drastic drop in fuel sooting tendency. …”
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184
An Analysis of Thermal Comfort at the School Outdoor Spaces: A Case Study of the American School of Creative Science, Dubai, UAE
Published 2022“…Outdoor school spaces are significant spaces which, regardless of a child’s residential area, provide great opportunity for outdoor space exploration leading to overall enhancement to the students’ wellbeing. …”
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185
Outcomes of POCUS‐Guided Peripheral Intravenous Access in Difficult Venous Access Patients: A Systematic Review and Meta‐Analysis
Published 2025“…A systematic review of 15 studies with 1485 patients, sourced from five databases, including PubMed, Cochrane Library, MEDLINE, Web of Science, and Google Scholar, showed POCUS significantly improved success rates (OR: 4.25), first‐attempt success (OR: 5.31), reduced attempts (MD: −0.83), and decreased procedure time (MD: −9.75 min). …”
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186
Estimation of power grid topology parameters through pilot signals
Published 2016“…The distribution grid has been the source of an increased amount of electricity production in recent years. …”
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187
Towards secure private and trustworthy human-centric embedded machine learning: An emotion-aware facial recognition case study
Published 2023“…However, despite the significant impact of AI design on human interests, the security and trustworthiness of edge AI applications are not foolproof and ethicalneither foolproof nor ethical; Moreover, social norms are often ignored duringin the design, implementation, and deployment of edge AI systems. …”
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188
The Impact of Nutritional Supplementation During Pregnancy on the Incidence of Gestational Diabetes and Glycaemia Control
Published 2022“…The release of placental hormones during pregnancy induces/ increases maternal insulin resistance and promotes nutrition utilization by the fetus. …”
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189
Intratumoral FoxP3<sup>+</sup>Helios<sup>+</sup> Regulatory T Cells Upregulating Immunosuppressive Molecules Are Expanded in Human Colorectal Cancer
Published 2017“…Levels of CD4<sup>+</sup>FoxP3<sup>+</sup>Helios<sup>+</sup> Tregs were significantly increased in the TME. Furthermore, we observed increased levels of PD-1/CTLA-4 and PD-1/CD39 co-expressing cells within FoxP3<sup>+</sup>Helios<sup>+</sup> and FoxP3<sup>+</sup>Helios<sup>−</sup> Treg subsets, indicative of their potent immunosuppressive potential. …”
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190
A Comprehensive Method of Ion Exchange Resins Regeneration and Its Optimization for Water Treatment
Published 2020“…Water conductivity, as an indicator of regeneration efficiency, was monitored over time at the different conditions and scenario. In general, it was observed that the conductivity decreases with time until one point is reached and then starts to increase as a result of resin saturation. …”
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191
Accelerating Care: Enhancing Patient Satisfaction through a Quality Initiative in the Obstetrics and Gynaecology Emergency Department at Al Wakra Hospital, Qatar
Published 2023“…The proportion of patients spending less than 8 hours in the OB ED observation beds rose from 74% in January 2022 to over 98% in 2023. …”
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192
Turkronicles: diachronic resources for the fast evolving Turkish language
Published 2025“…Our analysis reveals that the vocabulary has changed significantly and multiple spellings exist for several words. …”
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193
Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis
Published 2025“…Meta-regression showed a significant decrease in SSI incidence in HICs. Maternal factors, procedural aspects, and care quality were associated with SSI. …”
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194
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
Published 2022“…Moreover, MM, and QM induced a good elastase inhibition at 100 µg/ml compared to the standard epigallocatechin gallate. …”
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195
Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
Published 2019“…Amino acid profiles were unaffected by an acute increase in IR induced by the lipid infusion. IS was lower in PCOS (p < 0.001) and was further decreased by the lipid infusion in both PCOS and controls. …”
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196
Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
Published 2016“…Cell cycle arrest in the S phase was detected with each compound separately, while combined treatment only increased the production of fragmented DNA. Both compounds induced apoptosis through the extrinsic pathway after 24 hours; however, after 48 hours, the intrinsic pathway was activated by topotecan treatment only. …”
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197
CFD modeling of particle settling in drilling fluids: Impact of fluid rheology and particle characteristics
Published 2021“…This is more important for small particles where the Newtonian behavior is dominant and particle-induced shear rate is low. Ellipsoidal cuttings exhibited significantly greater resistance to settling as compared to spherical particles, mainly due to the increased drag force. …”
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198
Phase-separated polyvinylidene fluoride/ZnO composite microspheres as sunlight-driven photocatalysts
Published 2024“…The incorporation of 1–3 wt% ZnO increases the decomposition temperature to approximately 480 °C. …”
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199
A Comprehensive Review on Membrane Fouling: Mathematical Modelling, Prediction, Diagnosis, and Mitigation
Published 2021“…Membrane-based separation has gained increased popularity over the past few decades, particularly reverse osmosis (RO). …”
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200
Nutritional Status and Clinical Outcomes of Children with Medical Complexity in the United Arab Emirates: A Retrospective Cross-Sectional Study
Published 2025“…According to the CIAF, 75.1% exhibited at least one form of anthropometric failure, while 54.9% presented with multiple concurrent forms. No significant differences in WAZ, LAZ, or WLZ scores were observed based on sex or nationality. …”
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