Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…</p> <p>Our research shows a link between slower walking pace and higher COPD hospitalization risk, as well as decreased lung function (PEF, FEV1, FVC). We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

P4HA3 deficiency increased sensitization to immune checkpoint inhibitors and P4HA3 could predict the clinical therapeutic effect of PD-1 inhibitor (Camrelizumab). by Hong Yan Huang (20135965)

“…Breast MRI scan images showed that the tumor size of the two patients was significantly reduced after immunotherapy, and the tumor of second TNBC patient was achieved a pathological complete response (pcr), The red rectangles indicated tumors. …”

Data Sheet 1_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Data Sheet 2_Efficacy and safety of Tongxinluo capsules combined with conventional therapy for acute myocardial infarction: a systematic review and meta-analysis.zip by Dan Ouyang (554436)

“…The meta-analysis revealed that Tongxinluo capsule combined with conventional treatment significantly decreased the 1-month MACCE rate (RR = 0.62, 95% CI 0.47 to 0.81; p = 0.0007), along with the individual risks of 1-month MACCE, including cardiac death (RR = 0.68, 95% CI 0.50 to 0.93; p = 0.02) and myocardial reinfarction (RR = 0.11, 95% CI 0.01 to 0.94; p = 0.04). …”

Location of the study area. by Yunxia Zhang (30848)

“…<div><p>It is significant to explore the evolution pattern and driving mechanism of non-grain of cultivated land in the main grain-producing areas to promote the sustainable development of agriculture and guarantee national food security. …”

Image 1_Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers.tiff by Gaetano Zizzo (15853004)

“…Median length of stay (LOS) was 14 days, and mean ward-to-intensive care unit (ICU) transfer and in-hospital mortality rates were 11 and 26%, respectively; significant differences were observed over the years, with LOS peaks preceding mortality peaks by 1 year. …”

Table 1_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Influencing factor index system. by Yunxia Zhang (30848)

“…<div><p>It is significant to explore the evolution pattern and driving mechanism of non-grain of cultivated land in the main grain-producing areas to promote the sustainable development of agriculture and guarantee national food security. …”

Table 1_Burden of heart failure attributable to chronic kidney disease in older adults (1990–2021): an analysis from the global burden of disease study.docx by Wenli Liu (400084)

“…Background<p>Heart failure (HF) is a critical global health issue, with chronic kidney disease (CKD) as a significant contributing factor. Both primarily affect older adults, with prevalence rising substantially after age 60. …”

Data Sheet 1_Polyphenol-mediated microbiome modulation in STEMI patients: a pilot study.zip by Argul Issilbayeva (21398168)

“…Polyphenol supplementation significantly decreased the Firmicutes/Bacteroidetes ratio (p = 0.04) and increased beneficial bacteria such as Roseburia (p = 0.01), Agathobaculum sp. …”

Table 4_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”

Ozone-Induced Alterations in Rhizospheric Nitrogen Pools and Their Implications for N₂O Emissions in Rice Soil by Ziom Adam Michael (21751928)

“…Rhizospheric denitrifier populations decreased by 11%, whereas seasonal N₂O emission was decreased by 21% under e[O₃] as compared to CC. …”

Data Sheet 1_The effect of mepolizumab dosage form on treatment outcomes in severe asthma.pdf by Martina Vetchá (21143222)

“…</p>Results<p>Three months after initiation of administration, all methods showed improvement compared to the values at the beginning of treatment, with ER decreasing from a median of 4 to 0. Similarly, the median OCS decreased from 5 mg to 0 mg across all methods throughout the treatment. …”

Table 2_Burden of heart failure attributable to chronic kidney disease in older adults (1990–2021): an analysis from the global burden of disease study.docx by Wenli Liu (400084)

“…Background<p>Heart failure (HF) is a critical global health issue, with chronic kidney disease (CKD) as a significant contributing factor. Both primarily affect older adults, with prevalence rising substantially after age 60. …”

Image 2_Activation of mechanoreceptor Piezo1 inhibits enteric neuronal growth and migration in vitro.jpeg by Chioma Moneme (20457845)

“…Piezo1 inhibition also led to significantly increased neuronal migration, whereas Piezo1 activation resulted in significantly decreased neuronal migration and slower neuronal recovery from injury.…”

Image 1_Assessment of microstructural abnormalities in gray and white matter of minimal hepatic encephalopathy patients using diffusion kurtosis imaging and their associations with... by Qing Sun (492552)

“…</p>Results<p>The TBSS analysis results showed that MHE patients had significantly decreased fractional anisotropy (FA) in the temporal part of the left superior longitudinal fasciculus and decreased kurtosis fractional anisotropy (KFA) in the left corticospinal tract and anterior thalamic radiation (p < 0.05, threshold-free cluster enhancement corrected). …”

Supplementary Material for: Fetoscopic endoluminal tracheal occlusion in congenital diaphragmatic hernia: Unraveling the impact of prematurity and suboptimal fetal lung growth by figshare admin karger (2628495)

“…In univariate analyses, the balloon inflation duration (p=0.05), the use of extracorporeal life support (p=0.04), and the post-balloon o/e LHR (p=0.04) were associated with survival, while in a multivariable logistic regression, the change in o/e-LHR after FETO (OR=1.07, p=0.05) was the only variable found to be significantly associated with survival. Conclusion Prematurity and SFLG are critical factors linked to decreased survival in FETO, with improved o/e-LHR correlating with better outcomes. …”

<b>Contrasting strategies, shared risk: 12-yr nitrogen addition compromises hydraulic safety in young and mature trees via distinct pathways</b> by Shijie Ning (17757825)

“…We found that, in young trees, N50 decreased soluble sugars in leaves, twigs, and branches, but increased in roots, suggesting a preferential belowground allocation, whereas N20 responses were limited. …”

Table 1_Clinical outcomes of frozen-thawed blastocysts with twice noninvasive chromosome screenings.docx by Yu Qiao (462684)

“…Compared with the morphological grading before the first freezing, the ICM grade of two embryos decreased from A to B, and the TE grade of two embryos decreased from B to C before the second freezing. …”

Table 2_Mendelian randomization and bioinformatics unveil potential links between gut microbial genera and colorectal cancer.xlsx by Long Wu (655081)

“…Background<p>Colorectal cancer (CRC) poses a significant global health burden, with high incidence and mortality rates. …”