The characteristics of <i>CALR</i> mutations in myeloproliferative neoplasms: a clinical experience from a tertiary care center in Qatar and a literature review by Mostafa Najim (14150400)

“…</p><h3>Conclusion</h3><p dir="ltr">The data shows a significant rise in CALR-positive MPN diagnoses in younger people, emphasizing the need for a better assessment tool to improve disease management and reduce complications.…”

Factors associated with mental health outcomes among medical residents exposed to COVID-19 by Mohamed Adil Shah Khoodoruth (14722588)

“…However, data on the psychological impact of infectious disease outbreaks, and COVID-19 in particular, on medical residents are relatively lacking.…”

Challenges of morbid obesity in gynecological practice by Albert A. Opoku (17019078)

“…Obesity affects several aspects of health, with increased risks of cardiovascular disease, diabetes, metabolic syndrome, and several malignancies.…”

A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle by Sanjay Kumar (8853)

“…By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. It increases the solubility of flavonoids leading to reduced toxicity and higher bioavailability. …”

Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line by Toutounji, Mohamad

“…The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran sulfate sodium (DSS)-induced IBD-like phenotype of intestinal Caco-2 cells in culture. DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …”
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Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

“…In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …”

Prevalence, correlates and management of hyperglycemia in diabetic non-critically Ill patients at a tertiary care center in Lebanon by El Khoury, Ghada

“…Background: Diabetes Mellitus is a chronic metabolic disease that affects 387 million people around the world. …”
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Type II diabetes mellitus and hyperhomocysteinemia: a complex interaction by Daniel E. Platt (13982757)

“…</p><h3>Results</h3><p dir="ltr">We found that Hc levels were significantly reduced among subjects with diabetes compared to those without diabetes when adjusted for all potential confounders (OR 0.640; 95% CI [0.44–0.92]; <i>p</i> = 0.0200). …”

Whole-Genome Molecular Characterization and Typing of Staphylococcus aureus Isolated from Lebanon by El Hassan, Sarah

“…Using the SCCmecFinder, we were able to predict the mec cassettes and showed that the SSA11 harbored a pseudo-SCCmec element resembling the one detected SCCmec type IV(2B). …”
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Prognostic effects of cardiopulmonary resuscitation (CPR) start time and the interval between CPR to extracorporeal cardiopulmonary resuscitation (ECPR) on patient outcomes under e... by Amir Vahedian-Azimi (11177056)

“…This understanding of their distinct predictive abilities enables medical professionals to identify high-risk patients more accurately and customize their interventions accordingly.…”

Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases by Hirbli, K.

“…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …”
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Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report by Fawzia M. Elgharbawy (17045534)

“…(lle259*). Sirolimus significantly reduced DNTs and substantially relieved the patient’s clinical symptoms.…”

A GHRHR founder mutation causes isolated growth hormone deficiency type IV in a consanguineous Pakistani family by Safeer Ahmad (9079257)

“…</p><h3>Results</h3><p dir="ltr">All affected individuals presented with a short stature without gross skeletal anomalies and significantly reduced serum GH levels. Genetic mapping revealed a homozygous nonsense mutation [NM_000823:c.G214T:p.…”

Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide. by Sara, Sokary

“…Semaglutide also slowed weight regain and promoted weight loss after failed bariatric surgery. It also significantly reduced ad libitum energy intake, decreased hunger, and increased satiety in multiple trials. …”
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Cathelicidin LL-37-induced transcriptome of human keratinocyte identifies chemokine CXCL10 link to T cell-mediated rosacea pathogenesis via JAK-1/STAT-1 pathway by Abdul W. Ansari (14557391)

“…<p dir="ltr">Rosacea is a chronic inflammatory disease of facial skin with unknown pathophysiology. …”

Initial risk assessment for pulmonary hypertension in patients with COPD by Yammine, Joe

“…Diffusion capacity was lower but did not reach statistical significance (P = 0.07). In multivariate analysis, statistically significant independent variables were >3% decrease in exercise oxyhemoglobin saturation and decline in prebronchodilator FEV1 (P = 0.01 and P = 0.04, respectively). …”
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Encapsulation and Release of Calcein from Herceptin-conjugated eLiposomes by Zafar, Mah Noor

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Carbon dioxide insufflation during ERCP for reduction of postprocedure pain by Azar, Riad

“…Patients: This study involved consecutive patients presenting for ERCP, excluding those with significant preprocedure pain or obstructive lung disease. …”
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The role of protective genetic variants in modulating epigenetic aging by Yosra Bejaoui (8552574)

“…At the same time, several protective variants have also been discovered that can reduce the risk of developing certain age-related disorders. …”

The Impact of Adopting Positive Education and Wellbeing Culture on Learners with Special Educational Needs and Disabilities (SEND) in a Private and Mainstream School in Dubai: An E... by Keis, Yasmina

“…It is worth mentioning that during Covid-19, schools across the globe and in UAE were closed as an effective control and safety measure to reduce the spread of the disease (Viner et al. 2020) and distance learning (DL) was introduced in March 2020. …”
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