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121
The Relationship between Smoking Cessation and Health Insurance Coverage: An Analysis of Cost Saving and Health Outcomes
منشور في 2023"…The use of tobacco products remains a significant public health concern worldwide, with smoking being a leading cause of preventable death and disease. …"
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122
Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis
منشور في 2020"…Remarkably, Africans seem to carry extremely lower frequencies of SARS-CoV-1 susceptibility alleles, reaching to 32-fold decrease compared to other populations.</p><h3>Conclusion</h3><p dir="ltr">Multiple genetic variants, which could potentially modulate SARS-CoV-2 infection, are significantly variable between populations, with the lowest frequency observed among Africans. …"
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123
Challenges in child and adolescent health across the Arab Gulf countries—Focus on metabolic health
منشور في 2025"…The combination of an increasing youth population combined with rapid modernisation, increasing per capita income and the paradigm shift towards unhealthy and affluent lifestyles has created a significant burden of non‐communicable diseases (NCDs), especially obesity and diabetes. …"
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124
Do near-bedtime usage of smartphones and problematic internet usage really impact sleep? A study based on objectively recorded usage data
منشور في 2023"…</p><h3> Results</h3><p dir="ltr">The multivariate linear regression showed that the increase in PIU (β = −0.231, p < 0.001) and smartphone usage two hours before sleep (β = −0.246, p < 0.001) led to decrease in sleep duration. Regarding sleep distraction, multivariate linear regression analysis revealed that two hours before sleep was a significant and positive predictor of sleep distraction (β = 0.197, p = 0.003), whereas PIU was not significant. …"
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125
Type II diabetes mellitus and hyperhomocysteinemia
منشور في 2017"…Results We found that Hc levels were significantly reduced among subjects with diabetes compared to those without diabetes when adjusted for all potential confounders (OR 0.640; 95% CI [0.44–0.92]; p = 0.0200). …"
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126
The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects
منشور في 2022"…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …"
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127
Efficacy and safety of aldafermin in non-alcoholic steatohepatitis: A systematic review and meta-analysis of randomized controlled trials
منشور في 2024"…<h3>Background</h3><p dir="ltr">Non-alcoholic steatohepatitis (NASH) is an advanced subtype of non-alcoholic fatty liver disease (NAFLD). NASH prevalence is increasing exponentially and carries a high risk for disease progression, cirrhosis, and liver-related mortality. …"
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128
Why do some countries produce more capital intensive output than others?
منشور في 2016"…Based on my model I offer an explanation for the variation in physical capital intensity across countries where the model predictions show that a lower quality of governance in a country results in a decrease in the output of capital-intensive goods and an increase in the output of labor-intensive goods. …"
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129
On the benefits of sleep
منشور في 2015"…It is well known that sleep deprivation can significantly affect cognitive functions such as attention and memory. …"
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130
Safety and efficacy of ensifentrine in COPD: A systemic review and meta-analysis
منشور في 2024"…<h3>Background</h3><p dir="ltr"><u>Chronic obstructive pulmonary disease </u>(COPD) significantly impacts global health due to persistent airflow limitation and inflammation. …"
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131
Comparative Transcriptome Analysis Reveals That Exendin-4 Improves Steatosis in HepG2 Cells by Modulating Signaling Pathways Related to Lipid Metabolism
منشور في 2022"…We compared the transcriptome profiles of untreated steatotic, and Ex-4-treated steatotic cells, and used Ingenuity Pathway Analysis (IPA) to identify the signaling pathways and associated genes involved in the protective effect of Ex-4. Ex-4 treatment significantly reduces steatosis. RNA-seq analysis revealed 209 differentially expressed genes (DEGs) between steatotic and untreated cells, with farnesoid X receptor/retinoid X receptor (FXR/RXR) (p = 8.9 × 10<sup>−7</sup>) activation being the top regulated canonical pathway identified by IPA. …"
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132
The characteristics of <i>CALR</i> mutations in myeloproliferative neoplasms: a clinical experience from a tertiary care center in Qatar and a literature review
منشور في 2024"…</p><h3>Conclusion</h3><p dir="ltr">The data shows a significant rise in CALR-positive MPN diagnoses in younger people, emphasizing the need for a better assessment tool to improve disease management and reduce complications.…"
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133
Factors associated with mental health outcomes among medical residents exposed to COVID-19
منشور في 2021"…However, data on the psychological impact of infectious disease outbreaks, and COVID-19 in particular, on medical residents are relatively lacking.…"
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134
Challenges of morbid obesity in gynecological practice
منشور في 2023"…Obesity affects several aspects of health, with increased risks of cardiovascular disease, diabetes, metabolic syndrome, and several malignancies.…"
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135
A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle
منشور في 2022"…By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. It increases the solubility of flavonoids leading to reduced toxicity and higher bioavailability. …"
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136
Dextran Sodium Sulfate-Induced Impairment of Protein Trafficking and Alterations in Membrane Composition in Intestinal Caco-2 Cell Line
منشور في 2020"…The present study investigates endoplasmic reticulum (ER) stress in addition to alterations in protein and membrane trafficking in a dextran sulfate sodium (DSS)-induced IBD-like phenotype of intestinal Caco-2 cells in culture. DSS treatment significantly reduced the transepithelial electric resistance (TEER) and increased the epithelial permeability of Caco-2 cells, without affecting their viability. …"
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137
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. High expression of <i>CCL5</i> in breast tumors was significantly associated with an increased OVS in all BC patients, but particularly in TNBC/Basal-like patients. …"
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138
Prevalence, correlates and management of hyperglycemia in diabetic non-critically Ill patients at a tertiary care center in Lebanon
منشور في 2019"…Background: Diabetes Mellitus is a chronic metabolic disease that affects 387 million people around the world. …"
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139
Type II diabetes mellitus and hyperhomocysteinemia: a complex interaction
منشور في 2017"…</p><h3>Results</h3><p dir="ltr">We found that Hc levels were significantly reduced among subjects with diabetes compared to those without diabetes when adjusted for all potential confounders (OR 0.640; 95% CI [0.44–0.92]; <i>p</i> = 0.0200). …"
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140
Whole-Genome Molecular Characterization and Typing of Staphylococcus aureus Isolated from Lebanon
منشور في 2020"…Using the SCCmecFinder, we were able to predict the mec cassettes and showed that the SSA11 harbored a pseudo-SCCmec element resembling the one detected SCCmec type IV(2B). …"
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masterThesis