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Predictors of Mortality in Veno-Arterial Extracorporeal Membrane Oxygenation Regardless of Early Left Ventricular Unloading: A National Experience
منشور في 2025"…In-hospital 30-day mortality occurred in 42.7% among those who received VA-ECMO support regardless of IABP use, while it was 46.9% among those receiving early LV unloading with IABP. The significant positive predictors of mortality with VA-ECMO regardless of IABP in CS were CPR > 20 minutes (aOR 14.74, 95% CI 2.02-107.41; p-value= 0.008), older age (i.e., greater than 55 years) and LM disease of more than 50% stenosis were associated with a fourfold increase in the odds of mortality while on VA-ECMO. …"
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Circulating Endothelial Microparticles Reduce in Concentration Following an Exercise Programme in Women With Polycystic Ovary Syndrome
منشور في 2019"…</p><h3>Results</h3><p dir="ltr">CD105+MP significantly reduced in women with PCOS from pre to post-exercise programme, with CD105+ MP reducing from 2114 CD105+ MP per μl platelet free plasma (PFP) to 424 CD105+ MP per μl PFP (<i>p</i> = 0.025). …"
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Two-surgeon technique of parenchymal transection contributes to reduced transfusion rate in patients undergoing major hepatectomy
منشور في 2010"…Although transfusion rates can be reduced to almost 0 in uncomplicated hepatectomies, the blood transfusion rates associated with liver resection remain significant at tertiary referral centers, such as ours. …"
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Extended Preoperative Chemotherapy Does Not Improve Pathologic Response and Increases Postoperative Liver Insufficiency After Hepatic Resection for Colorectal Liver Metastases
منشور في 2010"…Results Treatment consisting of ≥9 cycles was not associated with an increase in complete or major pathologic response (SD vs. …"
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28
An imageable retinoid acid derivative to detect human cancer xenografts and study therapeutic dosing to reduce its toxicity
منشور في 2010"…Those agents will specifically target the disease markers for diagnosis and apply the biologically effective dose for treatment. …"
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29
Does colchicine reduce mortality in patients with COVID-19 clinical syndrome? An umbrella review of published meta-analyses
منشور في 2023"…BackgroundDespite significant improvements in both treatment and prevention strategies, as well as multiple commissioned reviews, there remains uncertainty regarding the survival benefit of repurposed drugs such as colchicine in patients with Coronavirus Disease 2019 (COVID-19) clinical syndrome. …"
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Does colchicine reduce mortality in patients with COVID-19 clinical syndrome? An umbrella review of published meta-analyses
منشور في 2023"…<h3>Background</h3><p dir="ltr">Despite significant improvements in both treatment and prevention strategies, as well as multiple commissioned reviews, there remains uncertainty regarding the survival benefit of repurposed drugs such as colchicine in patients with Coronavirus Disease 2019 (COVID-19) clinical syndrome.…"
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Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients
منشور في 2022"…Vaccinating diabetic patients against influenza would significantly reduce hospitalization due to disease severity. …"
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Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases
منشور في 2017"…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…"
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Being female with vitiligo disease in traditional societies within North Africa
منشور في 2024"…However, the illness profoundly impacted patients’ lives emotionally, with clear consequences, including diminished emotional satisfaction and reduced social participation. The results of this study highlight the negative effects that vitiligo disease can have on women’s quality of life within traditional Libyan society. …"
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Systematic analysis of healthcare big data analytics for efficient care and disease diagnosing
منشور في 2022"…It contains a gigantic amount of data, especially a plethora of data types that has been significantly useful in diverse research domains. In healthcare domain, the researchers use computational devices to extract enriched relevant information from this data and develop smart applications to solve real-life problems in a timely fashion. …"
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Air pollution burden of disease over highly populated states in the Middle East
منشور في 2023"…</p><h3>Conclusions </h3><p dir="ltr">The results indicate a significant impact of air pollution due to long-term exposure to fine particles resulting in early mortality. …"
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease
منشور في 2015"…For patients not sufficiently controlled on a single long-acting bronchodilator, a combination of different bronchodilators has shown a significant increase in lung function. Tiotropium, a once-daily dosing LAMA, demonstrated sustained improvements in lung function as well as improved health-related quality of life, reduced exacerbations, and increased survival without altering the rate of decline in the mean forced expiratory volume in 1 second (FEV1) with fairly tolerable side effects. …"
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Gut Microbiota in Familial Mediterranean Fever: Insights into Microbial Patterns and Disease Severity
منشور في 2025"…Our findings revealed no significant differences in gut microbiota composition or diversity between FMF patients and healthy controls, nor among FMF subgroups stratified by disease severity. …"
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masterThesis -
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Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease
منشور في 2023"…<p dir="ltr">Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. …"
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Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway
منشور في 2022"…Further treatment with 200 nM Ex-4 for 3 h significantly reduced the OA-induced lipid accumulation (p < 0.05). …"