DataSheet1_Feasibility exploration of GSH in the treatment of acute hepatic encephalopathy from the aspects of pharmacokinetics, pharmacodynamics, and mechanism.DOCX by Kangrui Hu (18718429)

“…Additionally, oral GSH demonstrated neuroprotective effects by alleviating the accumulation of intracerebral glutamine, down-regulating glutamine synthetase, and reducing taurine exposure. Pharmacokinetic studies suggested that AHE modeling led to significant decrease in hepatic and cerebral exposure of GSH and cysteine. …”

Data Sheet 1_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.xlsx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Image1_Hemopexin alleviates sterile inflammation in ischemia-reperfusion-induced lung injury.tif by Tomoyuki Nakagiri (3765511)

“…</p>Results<p>Our results demonstrate that treatment with Hx alleviated histopathological signs of inflammation in ischemic lungs, as evidenced by a reduction in the number of infiltrating neutrophils and decreased levels of perivascular edema. In addition, thrombotic vaso-occlusion in pulmonary blood vessels of IRI lungs was reduced by Hx. …”

Enhancing <i>o</i>-cresol biodegradation in wastewater via <i>T. obliquus</i>/TiO₂ composite: construction and mechanistic insights by Daohong Zhang (1746094)

“…The TiO₂ NPs interact with chloroplasts to reduce bandgap, decrease photoelectron-hole recombination, and improve light energy utilization. …”

Data Sheet 2_Investigating the impact of microcalcification size and volume on collagenous matrix and tissue mechanics using a tissue-engineered atherosclerotic cap model.docx by Imke L. Jansen (22089944)

“…To mimic human microcalcification size and volume, hydroxyapatite microparticles, in two size ranges (diameter up to 5 μm or up to 50 μm) and two volumes (1 v/v% and 5 v/v%) were incorporated homogenously throughout the tissue-engineered model. 5 v/v% of particles caused a significant lowering of the mechanical properties as was shown by a decrease in stiffness and ultimate tensile stress under uniaxial tensile loading. …”

Tailoring Optical and Structural Properties of PVP/Chitosan Blend Films via In-Situ Synthesized Silver Nanoparticles by Viyan J. Jalal (22032376)

“…UV–Vis spectroscopy confirmed that lower crystallinity corresponds to a reduced absorption edge, a decrease in direct band gaps and indirect band gap energy, and an increase in Urbach energy. …”

Data Sheet 1_Enhanced computerized cognitive remediation therapy improved cognitive function, negative symptoms, and GDNF in male long-term inpatients with schizophrenia.zip by Peiyun Zhang (4484194)

“…Moreover, improvements in list recall were associated with reduced negative symptoms. Additionally, CCRT ameliorated the decrease in serum GDNF levels in patients with schizophrenia.…”

Image 1_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”

Table 2_The comparison of remimazolam and midazolam in bronchoscopic sedation: a systematic review and meta-analysis of randomized controlled trials.docx by Yahya Kayed AbuJwaid (21676193)

“…</p>Conclusion<p>Remimazolam may reduce induction and recovery times and decrease the need for rescue sedation compared to midazolam. …”

Image 2_Multi-omics analysis reveals neutrophil heterogeneity and key molecular drivers in sepsis-associated acute kidney injury.jpg by Tianle Cheng (20788417)

“…We identified four neutrophil subtypes—pro-inflammatory, anti-inflammatory, mature, and immature—revealing a significant increase in pro-inflammatory neutrophils in sepsis (40.53% versus 4.19% in controls) and a decrease in anti-inflammatory neutrophils (18.43% versus 27.04%). …”

Table 1_The comparison of remimazolam and midazolam in bronchoscopic sedation: a systematic review and meta-analysis of randomized controlled trials.docx by Yahya Kayed AbuJwaid (21676193)

“…</p>Conclusion<p>Remimazolam may reduce induction and recovery times and decrease the need for rescue sedation compared to midazolam. …”

Comparative analysis of functional group effects on CO₂, CH₄, CO, and N₂ adsorption in UiO-66 and its derivatives by Prudhviraj Medikonda (20561356)

“…The selectivity of CO₂ over CH₄, CO, and N₂ showed that introducing larger and more complex functional groups caused a sudden decrease in selectivity with increasing temperature; this difference was more significant at lower temperatures and negligible at higher temperatures.…”

Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx by Bhavana Bhatnagar (11016429)

“…All patients achieved stable disease; however, a significant reduction in bone marrow blast percentage after one to two cycles of treatment was observed in two patients, which correlated with a decrease in FLT3-ITD allelic ratio and variant allele frequency of co-occurring mutations (e.g., NPM1 and DNMT3A). …”

community_experiment_and_pure_culture.xlsx by Wen-Wen Huang (22122439)

“…In both experiments, PE and PVC significantly reduced viral abundances. However, their effects on bacterial abundances were context-dependent. …”

Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d... by Carol Costa Encarnação (21412730)

“…Additionally, OB EVs caused metabolic changes, including reduced lactate levels and decreased pyruvate kinase (PK) activity, while increasing glucose-6-phosphate dehydrogenase (G6PDH) activity, suggesting metabolic reprogramming that supports tumor cell survival and proliferation. …”

Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx by Yang Guo (399435)

“…</p>Conclusion<p>Patients with OSA exhibit reduced diversity, changes in bacterial abundance, and altered structure in the microbiota, especially in the gut microbiota. …”

RICTOR silencing inhibits cell proliferation via UGCG regulation. by Mohammad Nafees Ansari (22232505)

“…(<b>E</b>) Heat map representing normalized absolute quantitation of ceramides and glucosylceramides in MCF-7_RICTOR^SH and MCF-7 cells. (<b>F</b>) Fold change (mean ± SEM, <i>n</i> = 5) in different sphingolipid species reveals an increase in ceramides and a decrease in glucosylceramides in MCF-7_RICTOR^SH cells compared to MCF-7 cells. …”

Supplementary file 1_Therapeutic potential of formononetin in cirrhotic portal hypertension: modulating hepatic fibrosis, macrophage polarization, and lymphangiogenesis.doc by Zhenghao Wu (9732511)

“…For in vitro experiments, hepatic stellate cells, macrophages and lymphatic endothelial cells were used to observe the multiple effects of FN.</p>Results<p>FN significantly ameliorated portal pressure in cirrhosis-induced PHT, improved liver function, and reduced liver fibrosis and hepatic stellate cell activation with decreased SMAD3 protein expression. …”

Data Sheet 1_Differential effects of physical activity on behavioral and prefrontal responses during repetitive inhibitory control in older adults.docx by Jae-Hoon Lee (334543)

“…The PA group showed a significant decrease in reaction time across repetitions (p < 0.001), whereas no such change was observed in the PI group. …”

Data Sheet 1_The role of lycopene in alleviating soybean meal-induced intestinal injury in an early-weaned piglet model.docx by Shugui Zheng (18151898)

“…</p>Results<p>Dietary lycopene significantly improved average daily gain (ADG) and average daily feed intake (ADFI) while reducing incidence of diarrhea in early-weaned piglets. …”