Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

“…Furthermore, OCT1 protein expression decreased after 1 h and 1 day of HH exposure (P < 0.05), while P-gp expression decreased after 1 h (P < 0.05).…”

Table 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.xlsx by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Insight into Greenhouse Gas Emission Characteristics of Light-Duty Vehicles in China Driven by Technological Innovation by Xinping Yang (17371783)

“…As anticipated, with advancements in emission standards and powertrains, vehicular GHG emissions have significantly decreased. However, our findings also revealed surprising trends. …”

Table 2_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.xlsx by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Image 1_Vitamin K protects against lipopolysaccharide-induced intestinal inflammation in piglets by inhibiting the MAPK and PI3K-AKT pathways.pdf by Huakai Wang (505567)

“…</p>Results<p>Morphological analysis revealed that VK significantly restored the decreased villus height and ratio of villus height to crypt depth induced by LPS. …”

Image 2_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Data Sheet 1_Growth regulation mechanism of Rhododendron moulmainense to high-temperature stress: integrated physiological, transcriptomic, and metabolomic insights.docx by Zaid Khan (625790)

“…Scanning electron microscopy resulted in reduced leaf stomatal traits, altering gas exchange, and thus, photosynthetic rates were decreased. …”

Image 1_Growth regulation mechanism of Rhododendron moulmainense to high-temperature stress: integrated physiological, transcriptomic, and metabolomic insights.jpg by Zaid Khan (625790)

“…Scanning electron microscopy resulted in reduced leaf stomatal traits, altering gas exchange, and thus, photosynthetic rates were decreased. …”

Image 2_Growth regulation mechanism of Rhododendron moulmainense to high-temperature stress: integrated physiological, transcriptomic, and metabolomic insights.jpg by Zaid Khan (625790)

“…Scanning electron microscopy resulted in reduced leaf stomatal traits, altering gas exchange, and thus, photosynthetic rates were decreased. …”

Table 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.docx by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

DataSheet1_Effects of Abelmoschus manihot (L.) and its combination with irbesartan in the treatment of diabetic nephropathy via the gut–kidney axis.PDF by Hongmei Yu (584700)

“…</p>Results<p>After treatment with HKC, EB, and their combination for 4 weeks, the urinary albumin-to-creatinine ratios decreased significantly in the db/db mice with DN. …”

Image 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Table 1_Growth regulation mechanism of Rhododendron moulmainense to high-temperature stress: integrated physiological, transcriptomic, and metabolomic insights.xlsx by Zaid Khan (625790)

“…Scanning electron microscopy resulted in reduced leaf stomatal traits, altering gas exchange, and thus, photosynthetic rates were decreased. …”

Image 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Table 1_Effects of selenium-mediated RUNX2 overexpression and its transcriptome alterations on Chondrocyte injury in Kashin Beck disease.docx by Di Zhang (197959)

“…</p>Results<p>The proportion of RUNX2-positive cells in KBD cartilage was significantly higher than in controls. RUNX2 mRNA levels were elevated, whereas methylation levels were reduced in KBD samples. …”

Data Sheet 1_HAX1, gene responsible for Kostmann syndrome, regulates gingival epithelial barrier function via intracellular trafficking of JAM1.pdf by Keita Tanigaki (13162449)

“…In HAX1-knockdown IHGE cells, significantly decreased levels of JAM1 were found. Additionally, cisplatin, a chemotherapeutic agent reported to inhibit HAX1, also led to decreased expression of both HAX1 and JAM1. …”

Image 1_Unveiling the intricacies: small interfering RNA targeting Snail-1 unravels dynamics in endometrial carcinoma cell behavior.jpeg by Feng Li (30515)

“…</p>Results<p>Transfection with 60 pmol/mL of Snail-1-specific siRNA significantly reduced Snail-1 expression at both the mRNA and protein levels. …”

Image 1_Modulating effects of Phellinus linteus polysaccharides on antioxidant capacity, immune function, intestinal function and microbiota in lipopolysaccharide-challenged broile... by Yang Li (7082)

“…The results demonstrated that LPS significantly decreased average daily gain (ADG), average daily feed intake (ADFI), and total antioxidant capacity (T-AOC) activity in serum and duodenum. …”

Data Sheet 2_Comprehensive analysis of SQOR involvement in ferroptosis resistance of pancreatic ductal adenocarcinoma in hypoxic environments.docx by Quan Lin (5958)

“…</p>Results<p>PDAC exhibited significantly higher hypoxia levels than normal tissues, correlating with reduced overall survival in patients. …”

Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... by Huijing Ren (19986303)

“…The results demonstrated that the combined administration of these 4 components (CPGB) had superior mitigating effects on AD cell model, as evidenced by the reduced pro-inflammatory cytokine production and decreased deposition of Aβ protein. …”