Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases by Mazhar Pasha (11197767)

“…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…”

Predictive Power of Random Forests in Analyzing Risk Management in Islamic Banking by Ahmet Faruk Aysan (11902115)

Gut Microbiota in Familial Mediterranean Fever: Insights into Microbial Patterns and Disease Severity by Rukaya Basala

“…Our findings revealed no significant differences in gut microbiota composition or diversity between FMF patients and healthy controls, nor among FMF subgroups stratified by disease severity. …”
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Combined bronchodilators (tiotropium plus olodaterol) for patients with chronic obstructive pulmonary disease by Ramadan, Wijdan H.

“…For patients not sufficiently controlled on a single long-acting bronchodilator, a combination of different bronchodilators has shown a significant increase in lung function. Tiotropium, a once-daily dosing LAMA, demonstrated sustained improvements in lung function as well as improved health-related quality of life, reduced exacerbations, and increased survival without altering the rate of decline in the mean forced expiratory volume in 1 second (FEV1) with fairly tolerable side effects. …”
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Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease by Sudharsana Sundarrajan (3181371)

“…<p dir="ltr">Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. …”

Systematic analysis of healthcare big data analytics for efficient care and disease diagnosing by Sulaiman Khan (12585349)

“…It contains a gigantic amount of data, especially a plethora of data types that has been significantly useful in diverse research domains. In healthcare domain, the researchers use computational devices to extract enriched relevant information from this data and develop smart applications to solve real-life problems in a timely fashion. …”

Air pollution burden of disease over highly populated states in the Middle East by Rima J. Isaifan (8350056)

“…</p><h3>Conclusions </h3><p dir="ltr">The results indicate a significant impact of air pollution due to long-term exposure to fine particles resulting in early mortality. …”

Exendin-4 alleviates steatosis in an in vitro cell model by lowering FABP1 and FOXA1 expression via the Wnt/-catenin signaling pathway by Olfa Khalifa (10914452)

“…Further treatment with 200 nM Ex-4 for 3 h significantly reduced the OA-induced lipid accumulation (p < 0.05). …”

Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study by Shubham Chauhan (21334742)

“…While prevalence rates experienced a minor decline, Disability‐Adjusted Life Years (DALYs) rose from 272.02 to 308.27 per 100,000, reflecting an increasing burden of the disease. Notably, Nepal significantly reduced its incidence rates, while Pakistan saw an increase in mortality rates. …”

Whole blood DNA aberrant methylation in pancreatic adenocarcinoma shows association with the course of the disease by El Maarri, Osman

“…Pancreatic tumors are usually diagnosed at an advanced stage in the progression of the disease, thus reducing the survival chances of the patients. …”
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Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

“…</p><p><br></p><h3>Methods</h3><p dir="ltr">We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study. …”

The role of preoperative transfusion in sickle cell disease, a systematic review and meta-analysis by Yasamin Abdu (15899155)

“…Notably, the increased bleeding risk observed seldom had clinical significance. We recommend individualizing management strategies, considering the overall positive impact of transfusions in reducing complications. …”

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…When performed within 4 weeks of chemotherapy, PET had a negative predictive value of 13.3% and a positive predictive value of 94.3%. …”
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Favipiravir for the treatment of coronavirus disease 2019 pneumonia; a propensity score-matched cohort study by Rand A. Alattar (9538554)

Prediction of critical total drawdown in sand production from gas wells: Machine learning approach by Fahd Saeed Alakbari (10701871)

“…Although some models are available for CTD prediction, most of them are proven to lack accuracy or use commercial software. …”

Using Data Mining and Text Mining Techniques in Predicting the Price of Real Estate Properties in Dubai by Khashan, Deena Younis Abo

“…The root mean squared errors RMSEs for all data subsets have decreased leading to enhancing the accuracy of prediction. …”
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Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma by Abdalla, Eddie

“…The presence of hepatitis did not significantly affect the survival rate, but hepatic fibrosis and vascular invasion predicted a decreased survival rate. …”
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Photobiomodulation Suppresses Alpha-Synuclein-Induced Toxicity in an AAV-Based Rat Genetic Model of Parkinson’s Disease by Abid Oueslati (816135)

“…This treatment also significantly reduced dopaminergic neuronal loss in the injected substantia nigra and preserved dopaminergic fibers in the ipsilateral striatum. …”

Serum metabolic signatures for Alzheimer’s Disease reveal alterations in amino acid composition: a validation study by Jonas Ellegaard Nielsen (21633062)

“…Pyruvic acid and valine were consistently reduced in the discovery and validation cohorts. Pathway analysis of significantly altered metabolites in the validation set revealed that they are involved in branched-chain amino acids (BCAAs) and energy metabolism (glycolysis and gluconeogenesis). …”

Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity by Mohamed A. Elrayess (7956179)

“…Functional enrichment analysis revealed long-chain polyunsaturated fatty acids (n-3 and n-6) as the pathway exhibiting the most significant changes with increased disease severity in hypertensive patients (FDR = 0.07).…”