Impacts of COVID-19 pandemic on environment, society, and food security حسب Hafiz Mohkum Hammad (17541432)

"…Environmental pollution was significantly reduced due to lockdown during the COVID-19 period. …"

The Prevalence and Genetic Spectrum of Familial Hypercholesterolemia in Qatar Based on Whole Genome Sequencing of 14,000 Subjects حسب Ilhame Diboun (3522413)

"…<p dir="ltr">Familial hypercholesterolemia (FH) is an inherited disease characterized by reduced efficiency of low-density lipoprotein-cholesterol (LDL-C) removal from the blood and, consequently, an increased risk of life-threatening early cardiovascular complications. …"

Impact of COVID‑19 pandemic restrictions and subsequent relaxation on the prevalence of respiratory virus hospitalizations in children حسب Ahmed Abushahin (17337703)

"…</p><h3>Conclusion</h3><p dir="ltr">Our study showed reduced viral ALRTI hospitalizations in Qatar during the COVID-19 pandemic with reduced RSV detection. …"

Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases حسب Hirbli, K.

"…This incidence was significantly higher than the calculated probability of the two diseases occurring by chance in the same patient. …"
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Neonatal autoimmune lymphoproliferative syndrome with a novel pathogenic homozygous FAS variant effectively treated with sirolimus: Case report حسب Fawzia M. Elgharbawy (17045534)

"…(lle259*). Sirolimus significantly reduced DNTs and substantially relieved the patient’s clinical symptoms.…"

Development of a cancer metastasis-on-chip assay for high throughput drug screening حسب Lutfiye Yildiz Ozer (17732619)

"…Further experimental analysis showed that Imatinib enhanced endothelial barrier stability as measured by trans-endothelial electrical resistance and significantly reduced the trans-endothelial invasion activity of tumor cells. …"

Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 حسب Olfa Khalifa (10914452)

"…Interestingly, knocking down MALAT1 significantly reduces the expression of CD36 in steatosis HepG2 cells in the presence of Ex-4. …"

Regulation of circulating CTRP-2/CTRP-9 and GDF-8/GDF-15 by intralipids and insulin in healthy control and polycystic ovary syndrome women following chronic exercise training حسب Jayakumar Jerobin (6595520)

"…Insulin suppressed CTRP9 levels during the intralipid study in both PCOS (P = 0.04) and control (P = 0.01) subjects. Exercise significantly reduced fasting GDF-8 levels in PCOS (P = 0.03) and control (P = 0.04) subjects; however, intralipids infusion after chronic exercise training increased GDF-8 levels in both PCOS (P = 0.003) and control (P = 0.05) subjects and insulin infusion during intralipid infusion reduced the rise of GDF-8 levels.…"

SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines حسب Hadeel T. Zedan (12535521)

"…Although post‐mRNA vaccination BTI elicited high levels of binding and NAbs, ADCC activity was significantly reduced. Also, there was no difference in ADCC levels across the four vaccines, although NAbs and binding antibody titers were significantly higher in mRNA‐vaccinated individuals. …"

Type II diabetes mellitus and hyperhomocysteinemia: a complex interaction حسب Daniel E. Platt (13982757)

"…</p><h3>Results</h3><p dir="ltr">We found that Hc levels were significantly reduced among subjects with diabetes compared to those without diabetes when adjusted for all potential confounders (OR 0.640; 95% CI [0.44–0.92]; <i>p</i> = 0.0200). …"

Effect of consanguinity on birth weight for gestational age in a developing country حسب Wakim, Gerard

"…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …"
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A multi-targeted approach to identify potential flavonoids against three targets in the SARS-CoV-2 life cycle حسب Sanjay Kumar (8853)

"…By examining the effects of glycosylation and other structural-activity relationships, the presence of sugar moiety in flavonoids significantly reduces its binding energy. It increases the solubility of flavonoids leading to reduced toxicity and higher bioavailability. …"

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis حسب Nabil, Shallik

"…Coronavirus disease 2019 (COVID-19) is an infectious disease caused by SARS-CoV-2, which was first discovered in Wuhan, China. …"
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Comparison of visible and near-infrared wavelength-excitable fluorescent dyes for molecular imaging of cancer حسب Adams, Kristen E.

"…Our images show that while both agents target EGFr, the EGF-IRDye® 800CW evidenced a significantly reduced background and enhanced the tumor-to-background ratio (TBR) compared to the EGF-Cy5.5. …"
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Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes حسب Abbas Khan (5141000)

"…<h3>Introduction</h3><p dir="ltr">Diabetes mellitus (DM) is recognized as one of the oldest chronic diseases and has become a significant public health issue, necessitating innovative therapeutic strategies to enhance patient outcomes. …"

High flow nasal oxygen (HFNO) in the treatment of COVID-19 infection of adult patients from – An emergency perspective: A systematic review and meta-analysis حسب Nabil Shallik (15900256)

"…<p>Coronavirus disease 2019 (COVID-19) is an infectious disease caused by SARS-CoV-2, which was first discovered in Wuhan, China. …"

Managing Endothelial Dysfunction in COVID-19 حسب Matli, Kamal

"…Background Coronavirus disease 2019 (Covid-19) is associated with endothelial dysfunction. …"
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Vitamin K2 supplementation and arterial stiffness among renal transplant recipients—a single-arm, single-center clinical trial حسب Kilany, Hala

"…Mean dp-ucMGP concentrations were also significantly reduced by 55.1% following menaquinone-7 supplementation with a reduction in the prevalence of subclinical deficiency by 40% ( P = .001). …"
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ABC transporter inhibition by beauvericin partially overcomes drug resistance in <i>Leishmania tropica</i> حسب Charbel Al Khoury (13167975)

"…The IC50 values, following BEA treatment, were significantly reduced from 30.83, 48.17, and 16.83 µM using ML to 8.14, 11.1, and 7.18 µM when using a combinatorial treatment (ML + BEA) against promastigotes, axenic amastigotes, and intracellular amastigotes, respectively. …"

Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report حسب Maysaloun Merhi (4246147)

"…The patient was treated with second-line treatment of nivolumab and had a stable disease for over 7 months. His NY-ESO-1 antibody was found to be lower after the third (****p < 0.0001) and the fifth (****p < 0.0001) cycles of treatment compared to base line, and this was in line with the stability of the disease. …"