Effect of fasudil on clinical outcomes of pulmonary hypertension: a systematic review and meta-analysis by Wanying Bao (19665769)

“…</p> <p>Inclusion of 3269 Group-3 PH patients demonstrated that Fasudil increased effective events, forced expiratory volume in one second (FEV₁), 6-minute walking distance (6MWD) and arterial partial pressure of oxygen (PaO₂), and decreased mean pulmonary artery pressure (mPAP) and pulmonary artery systolic pressure (PASP); Inclusion of 197 Group-2 PH patients suggested that Fasudil increased 6MWD and PaO₂, and decreased PASP. …”

Table_1_Combinatorial protection of cochlear hair cells: not too little but not too much.DOCX by Arwa Kurabi (344167)

“…All compounds were added at a dosage below that required for significant protection in the assay, and only this single dose was then employed. …”

Data Sheet 6_Experimental study on the correlation between pore evolution characteristics and seepage flow of loaded lignite.xlsx by Xi Zhang (83736)

“…The fractal dimension D₂ and D₃ values of pores in the medium and macropores scale range are close to 3, with the maximum value of D₂ being 2.971. This indicates significant fractal characteristics, suggesting that medium pores are the most developed in this scale range. …”

Analytical framework. by Yunxia Zhang (30848)

“…<div><p>It is significant to explore the evolution pattern and driving mechanism of non-grain of cultivated land in the main grain-producing areas to promote the sustainable development of agriculture and guarantee national food security. …”

Image 1_Unveiling the intricacies: small interfering RNA targeting Snail-1 unravels dynamics in endometrial carcinoma cell behavior.jpeg by Feng Li (30515)

“…Moreover, transfection correlated with increased apoptosis and decreased migration of treated HEC-1A cells.</p>Conclusion<p>The study emphasizes the significant influence of Snail-1 on EMT in EC cells, thereby impacting apoptosis and metastasis. …”

Trends in management of central cord syndrome: Insights from the New York State SPARCS database by Kevin Yoon (22393401)

“…The current study found that surgical management is associated with decreased probability of 90-day readmission and a non-significate decreased probability of mortality within 90 days of discharge.…”

Assessing cell viability with WST-8 assay. by Shepard C. Moore (22537510)

“…Normalized viability differences between cell lines exposed to (A) 100 µg/mL and (B) 500 µg/mL of uranium oxide particulates; A549 shows significantly decreased viability compared to HBTEC (p = 0.0047) and HSAEC (p = 0.0026) at 100 µg/mL. …”

Data Sheet 1_Global, regional, and national time trends in falls and their predictions: an age-period-cohort analysis of the Global Burden of Disease Study 2021.pdf by Huan Jiang (1672375)

“…</p>Conclusion<p>Falls among older adults remain a persistent global issue, with significant regional and intra-regional disparities in falls mortality. …”

Data Sheet 4_Epidemiology of inflammatory bowel disease-associated anemia in children and adolescents from 1990 to 2021: a global, regional analysis from the Global Burden of Disea... by Chenjing Xu (12109035)

“…</p>Conclusion<p>The ASPR of IBD-associated anemia in children and adolescents increased from 2005 to 2010 and then decreased after reaching a peak in 2010. In the future, IBD-associated anemia will continue to pose a significant public health problem.…”

Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

Behavioral characterization of prenatal nicotine exposure (PNE) and control mice. by Rodrigo Vidal (4177060)

“…Quantification of the average total distance traveled. Significant differences were observed between PNE animals and control mice (PNE: 78.37 ± 2.01 m; n = 6; Control = 51.57 ± 3.33 m; n = 6), t = 6,883 df = 10, p < 0,0001. …”

The effect of inulin treatment on plasma untargeted metabolomic profiles in mice of diverse groups. by Ke Li (106849)

“…Color key in the heat map represents the metabolite expression value: red represents the significant increases and blue stands for the remarkable decreases. …”

De-repression of endogenous retroelements triggers viral mimicry, interferon, and cytokine response. by Sarfraz Shafiq (13259589)

“…<p><b>(A)</b> Volcano plot of ATAC-seq results for sequence repeats with increased (blue) and decreased (red) chromatin accessibility in ATRX-null microglia. …”

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Table2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Image2_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…</p>Results<p>Acod1^−/− mice treated with LPS demonstrated decreased BALF levels of itaconate, TCA cycle reprogramming, decreased BALF neutrophils, increased lung CD4⁺ T cells, decreased BALF and lung levels of TNF-α, and decreased BALF CXCL1 compared to WT animals. …”

Cilium disassembly defects were rescued with ectopic expression of CCDC66 but not CEP104. by Jovana Deretic (13113617)

“…Mean cilia length measured in 3D in CCDC66 depletion is decreased to 0.97-fold of the mean control length. …”