Schematic model depicting the relationship between lipids and proteins by target gene knockdown. by Takuya Kitamoto (11721639)

Data_Sheet_1_Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke.docx by Jae-Sung Lim (532986)

“…</p>Results<p>Among 208 eligible patients, 11 decliners and 10 matched non-decliners were identified over an average follow-up of 5.7 years. No significant differences in cSVD markers were noted between the groups, except for white matter hyperintensities (WMHs), which were strongly linked with MMSE scores among decliners (rho = −0.85, p < 0.01). …”

Data Sheet 1_Radiomics reveals the biological basis for non-small cell lung cancer prognostic stratification by reflecting tumor immune microenvironment heterogeneity.docx by Qing Huang (240196)

“…Immune microenvironment profiling showed significantly reduced immune scores and decreased proportions of naive B cells in high-risk patients, indicating impaired immune activity. …”

Table 1_Transcriptional patterns of brain structural abnormalities in CSVD-related cognitive impairment.docx by Haixia Mao (3775582)

“…Furthermore, a total of 1,580 genes were revealed to be significantly associated with regional change in GMV. …”

Flowchart of the study population. by Emma Hertting (21568077)

“…<div><p>Objective</p><p>To investigate the effect of antenatal identification of small for gestational age (SGA) fetuses on perinatal and childhood outcomes, separately analyzing early- and late-onset fetal growth restriction (FGR).…”

Video 2_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…Small interfering RNA (siRNA) targeting the Bet1L gene was injected on a weekly basis into the hindlimb muscle of pre-symptomatic ALS and wild-type (WT) rats. …”

Video 1_Muscle-specific Bet1L knockdown induces neuromuscular denervation, motor neuron degeneration, and motor dysfunction in a rat model of familial ALS.mp4 by Adam Eckardt (20573576)

“…Small interfering RNA (siRNA) targeting the Bet1L gene was injected on a weekly basis into the hindlimb muscle of pre-symptomatic ALS and wild-type (WT) rats. …”

Occurrence of subcortical immature neurons (scINs) in the amygdala of mouse and primates: relationship with evolution of subnuclei scaling and cortical connectomics. by Marco Ghibaudi (16701750)

Data Sheet 1_Case Report: Micronized purified flavonoid fraction [Daflon]-induced bradycardia.pdf by Jhennyfer Aline Lima Rodrigues (10278251)

“…Because venous insufficiency decreased during the observed drug administration period, further studies are needed to examine whether the ability of diosmin and hesperidin to reduce vein disorders is directly linked to their action on heart rate.…”

Data Sheet 1_TREM-1 as a potential gatekeeper of neuroinflammatory responses: therapeutic validation and mechanistic insights in experimental traumatic brain injury.zip by Yunsheng Zhang (474242)

“…Spleen tyrosine kinase (SYK) inhibition was achieved using R406, and TREM-1 small interfering RNA (siRNA) and overexpressing plasmids were performed to validate its role in NF-κB signaling and pyroptosis quantified using WB and enzyme-linked immunosorbent assay (ELISA). …”

Table 1_Analysis of the microbiota of pregnant women in relation to weight gain during pregnancy – a pilot study.docx by Katarzyna Kosinska-Kaczynska (6794522)

“…However, in both sites none difference was found to be statistically significant after p-value correction.</p>Conclusions<p>Despite small sample size, we demonstrated slight trends in microbiota composition between groups. …”

Data Sheet 1_The impact of a home visiting program on the care environment of Brazilian adolescent mothers - an descriptive exploratory study.pdf by Letícia Aparecida da Silva (21178136)

“…From 12 to 24 months, both groups showed a tendency for the median to decrease, with a more marked decrease in the CG, which reached values lower than those previously observed. …”

Prognostic indicators and survival rates in vulvar cancer: insights from a retrospective study by Tharinee Rahong (21020147)

“…Additionally, a tumour size exceeding 4 cm in diameter was significantly linked with decreased OS (<i>p</i> = .001). …”

Continuing evolution of H5N1 highly pathogenic avian influenza viruses of clade 2.3.2.1a G2 genotype in domestic poultry of Bangladesh during 2018–2021 by Mohammed Nooruzzaman (3175290)

“…<p>We characterized 15 H5N1 HPAI viruses from different small- and medium-scale poultry flocks across Bangladesh during 2018–2021 based on their complete genome sequences. …”

Table 1_Correlation of serum irisin levels with diabetic nephropathy: an exhaustive systematic appraisal and meta-analytical investigation.xls by Yuan Deng (177795)

“…Background<p>Diabetic nephropathy (DN) is a major complication of diabetes, contributing significantly to end - stage renal disease. Irisin, an exercise - induced myokine, has been linked to metabolic disorders, but its relationship with DN remains unclear. …”

Image 4_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

Image 2_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

Image 1_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

Image 3_Unraveling impact and potential mechanisms of baseline pain on efficacy of immunotherapy in lung cancer patients: a retrospective and bioinformatic analysis.jpg by Zexin Zhang (7507979)

“…ELISA assay results indicated that the level of CXCL12 significantly decreased compared to baseline after pain was relieved.…”

Table 1_Co-frequency or contrary? The effects of Qiwei Baizhu Powder and its bioactive compounds on mucosa-associated microbiota of mice with antibiotic-associated diarrhea.docx by Zeli Zhang (3422570)

“…Mice in the N group and R group were gavaged with sterile water. 16S rRNA gene sequencing was used to investigate the changes of mucosa-associated microbiota (MAM) in the small intestine of mice. Moreover, the levels of diamine oxidase (DAO), D-Lactate, secretory immunoglobulin A (sIgA), interleukin 6 (IL-6), IL-10, and tumor necrosis factor-α (TNF-α) were detected using enzyme-linked immunosorbent assay (ELISA) kits. …”