Table 1_Association of oxidative balance score with metabolic syndrome and its components in middle-aged and older individuals in the United States.docx by Qu Zhang (486455)

“…</p>Results<p>Higher OBS quartiles were associated with a reduced MetS risk (OR 0.25; 95% confidence interval [CI]: 0.12–0.51; p < 0.0001), after adjusting for confounders. Increased OBS was linked to decreases in waist circumference (WC) (OR 0.41; 95% CI: 0.30–0.51; p < 0.0001), triglycerides (TG) (OR 0.71; 95% CI: 0.53–0.92; p = 0.0139), blood pressure (BP) (OR 0.53; 95% CI: 0.40–0.69; p < 0.0001), and fasting glucose (FG) (OR 0.61; 95% CI: 0.45–0.81; p < 0.0001), while HDL-C increased (OR 0.68; 95% CI: 0.51–0.90; p = 0.0065). …”

Table 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.xlsx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Data Sheet 1_Causality of genetically determined glucosamine supplementation on cognition and sarcopenia: a Mendelian randomization study.docx by Yi Kang (387134)

“…Background<p>Evidence indicates a negative link between glucosamine and age-related cognitive decline and sarcopenia. …”

Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025 by Alexandre Berthier (16876311)

“…</p><h3>Results</h3><p dir="ltr">Our study shows that temporarily blocking the insulin receptor in young mice leads to later-life liver issues by hindering PPARα-mediated adaptation to a high-fat diet. This is linked to decreased histone active marks at PPARα sites and reduced endogenous PPARα ligands. …”

Table_1_Major air pollution and climate policies in NYC and trends in NYC air quality 1998–2021.docx by Kathleen Lau (19855266)

“…Between 1998 and 2020, PAH concentrations decreased significantly by 66%.</p>Discussion/conclusion<p>While it is not possible to link improved air quality to a single policy, our analysis provides evidence of a cumulative beneficial effect of clean air and climate policies enacted between 1998 and 2021 both city-wide and in our cohorts residing in communities that have been disproportionately affected by air pollution. …”

Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip by Xueshan Chen (17477633)

“…Notably, highly expressed proteins in horse milk were closely linked to immune signaling pathways, functioning as immune modulators. …”

Image 1_The advanced lung cancer inflammation index as a predictor of kidney stone risk in men: a cross-sectional analysis.tif by Yan Zhou (6523)

“…Background<p>Kidney stone incidence and recurrence are increasing, which poses significant health problems. The Advanced Lung Cancer Inflammation Index (ALI) combines body mass index (BMI), albumin, and neutrophil-to-lymphocyte ratio (NLR). …”

Image 2_The advanced lung cancer inflammation index as a predictor of kidney stone risk in men: a cross-sectional analysis.tif by Yan Zhou (6523)

“…Background<p>Kidney stone incidence and recurrence are increasing, which poses significant health problems. The Advanced Lung Cancer Inflammation Index (ALI) combines body mass index (BMI), albumin, and neutrophil-to-lymphocyte ratio (NLR). …”

Table1_The association of physical activity with kidney function risk among adults with long working hours.docx by Tenglong Yan (14132220)

“…Introduction<p>Long working hours are likely associated with the decreased of kidney function, while physical activity (PA) was linked to improvements in kidney function. …”

Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

Table 1_The advanced lung cancer inflammation index as a predictor of kidney stone risk in men: a cross-sectional analysis.docx by Yan Zhou (6523)

“…Background<p>Kidney stone incidence and recurrence are increasing, which poses significant health problems. The Advanced Lung Cancer Inflammation Index (ALI) combines body mass index (BMI), albumin, and neutrophil-to-lymphocyte ratio (NLR). …”

DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

Multi-Omics Insights into Microbiome and Metabolite Signatures as Potential Biomarkers for Feline Hypertrophic Cardiomyopathy by Yuhong Wu (21545486)

“…Compared to healthy cats, those with HCM exhibited significant gut microbiota dysbiosis, including decreased abundances of <i>Campilobacterota</i>, <i>unclassified_k_norank_d_Bacteria</i>, <i>Blautia</i>, <i>Helicobacter</i>, and <i>Ruminococcus_torques_group</i>, while <i>Romboutsia</i> and <i>Lactococcus</i> were enriched in the HCM group. …”

Image 1_Bright light exposure reduces negative affect and modulates EEG activity in sleep-deprived and well-rested adolescents.tif by Jana Kopřivová (14754945)

“…</p>Results<p>Bright light significantly reduced negative affect and improved Digit Span Forward task performance. …”

Data Sheet 1_Microbiome-metabolome dysbiosis of bronchoalveolar lavage fluid of lung cancer patients.docx by Jing Wang (6206297)

“…Metabolites increased in lung cancer were Citric acid, N-Acetylneuraminic acid, Oxoglutaric acid, and Neopterin, whereas L-Tryptophan, Uridine, 3-Hydroxybutyric acid decreased. The KEGG pathways suggest a significant link between microbial presence and both tumorigenesis and progression.…”

Image 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.pdf by Liping Shi (734514)

“…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …”

Table 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.csv by Liping Shi (734514)

“…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …”

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”

Image1_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.jpeg by Aaron D. Schwab (18289974)

“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”