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significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significantly teer » significantly better (Expand Search), significantly weaker (Expand Search), significantly lower (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
significantly teer » significantly better (Expand Search), significantly weaker (Expand Search), significantly lower (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
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Data Sheet 1_Validation of an MPS-based intestinal cell culture model for the evaluation of drug-induced toxicity.docx
Published 2025“…Overall, from the 23 tested compounds, 15 showed the expected outcome, i.e., the compound led to a decrease of the TEER for the positive control compounds, or the TEER value remained stable after treatment with non-GI-toxic compounds.…”
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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The effect of HA digestion and HA replenishment alone or with CS on barrier function measured by TEER.
Published 2025“…PS decreased TEER. (C) Different treatments (treatment groups n = 8)with HA and/or CS did not affect TEER recovery after PS treatment, full recovery was seen in all groups after 24 hours. …”