Unveiling the molecular legacy of transient insulin resistance: Implications for hepatic metabolic adaptability (Sup Tables). Berthier et al. J. Hepatol. 2025 by Alexandre Berthier (16876311)

“…</p><h3>Results</h3><p dir="ltr">Our study shows that temporarily blocking the insulin receptor in young mice leads to later-life liver issues by hindering PPARα-mediated adaptation to a high-fat diet. This is linked to decreased histone active marks at PPARα sites and reduced endogenous PPARα ligands. …”

<p></p><p></p><p dir="ltr"><b>Trends in GP dispensing of thickeners in the NHS England, 2019-24</b></p> by ARLENE MCCURTIN (22819052)

“…Thickened liquids is primarily an intervention for older people although there was a significant decreasing trend in dispensed thickener items in adult populations. …”

Table 1_Changes in self-reported alcohol consumption at high and low consumption in the wake of the COVID-19 pandemic: a test of the polarization hypothesis.docx by Alexander Tran (11038679)

“…We also conducted a multivariate linear regression using mental well-being and sociodemographic variables as predictors of consumption.…”

Table_1_Major air pollution and climate policies in NYC and trends in NYC air quality 1998–2021.docx by Kathleen Lau (19855266)

“…Between 1998 and 2020, PAH concentrations decreased significantly by 66%.</p>Discussion/conclusion<p>While it is not possible to link improved air quality to a single policy, our analysis provides evidence of a cumulative beneficial effect of clean air and climate policies enacted between 1998 and 2021 both city-wide and in our cohorts residing in communities that have been disproportionately affected by air pollution. …”

Data Sheet 1_Association of body roundness index with cardiovascular disease in patients with cardiometabolic syndrome: a cross-sectional study based on NHANES 2009-2018.pdf by Xiaohua He (361530)

“…For CVD, stratified analyses did not show significant difference between strata. For CHF, BMI interacted with the association, with BRI being associated with decreased risk of CHF in a subgroup of normal weight subjects and increased risk of CHF in a subgroup of obese subjects. …”

Table 1_Association of serum iron with all-cause mortality and cardiovascular mortality in the cardiovascular patients: a retrospective cohort study based on the NHANES 1999–2018.d... by Jing Lu (120666)

“…Restricted cubic spline showed a nonlinear relationship between SI and all-cause mortality and a linear relationship between SI and cardiovascular mortality. …”

Table 1_Inner engineering is associated with perceived improvements in relationship quality, interpersonal connections, and interpersonal compassion.docx by Nashaw Jafari (20467640)

“…The following measures were used: the Positive-Negative Relationship Quality (PN-RQ) scale, Interpersonal Mindfulness Scale (IMS), Perceived Stress Scale (PSS), Compassion Scale (CS), and Flourishing Measure. Linear mixed-effects models were used to analyze the survey data, with p-values of < 0.05 considered statistically significant.…”

Association between Lyn tyrosine kinase and renal injury in patients with systemic lupus erythematosus by Jian Sun (27858)

“…Lyn levels negatively correlated with SLEDAI and 24-hour urine protein (24h-U-pro) while positively correlated with serum C3, C4, hemoglobin, and albumin. Multiple linear regression indicated an independent association between Lyn mRNA and SLEDAI. …”

Table 1_Association of rs440446 in the APOE intron region with multidimensional cognitive function, lipid/metabolic markers, and spontaneous neural activity in Chinese urban commun... by Zhiyuan Wang (535663)

“…Neuropsychological tests, lipid/metabolic markers (n = 326), and resting-state fMRI (rs-fMRI) data (n = 216) were collected. Multivariable linear regression was used to assess associations between rs440446 and cognitive performance, lipids, and metabolic indicators. …”

Table_1_Association between the Planetary Health Diet Index and biological aging among the U.S. population.DOCX by Shaoqun Huang (19810725)

“…Weighted multivariate linear models, restricted cubic spline (RCS), and subgroup analysis were subsequently carried out to evaluate the influence of PHDI on biological aging.…”

Data Sheet 1_Comparative analysis of proteomics and transcriptomics reveals novel mechanism underlying the antibacterial activity and immune-enhancing properties of horse milk.zip by Xueshan Chen (17477633)

“…Notably, highly expressed proteins in horse milk were closely linked to immune signaling pathways, functioning as immune modulators. …”

Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

Multi-Omics Insights into Microbiome and Metabolite Signatures as Potential Biomarkers for Feline Hypertrophic Cardiomyopathy by Yuhong Wu (21545486)

“…Compared to healthy cats, those with HCM exhibited significant gut microbiota dysbiosis, including decreased abundances of <i>Campilobacterota</i>, <i>unclassified_k_norank_d_Bacteria</i>, <i>Blautia</i>, <i>Helicobacter</i>, and <i>Ruminococcus_torques_group</i>, while <i>Romboutsia</i> and <i>Lactococcus</i> were enriched in the HCM group. …”

Image 1_Bright light exposure reduces negative affect and modulates EEG activity in sleep-deprived and well-rested adolescents.tif by Jana Kopřivová (14754945)

“…</p>Results<p>Bright light significantly reduced negative affect and improved Digit Span Forward task performance. …”

Data Sheet 1_Microbiome-metabolome dysbiosis of bronchoalveolar lavage fluid of lung cancer patients.docx by Jing Wang (6206297)

“…Metabolites increased in lung cancer were Citric acid, N-Acetylneuraminic acid, Oxoglutaric acid, and Neopterin, whereas L-Tryptophan, Uridine, 3-Hydroxybutyric acid decreased. The KEGG pathways suggest a significant link between microbial presence and both tumorigenesis and progression.…”

Image 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.pdf by Liping Shi (734514)

“…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …”

Table 1_Understanding the influence of plant genetic factors on rhizosphere microbiome assembly in Panax notoginseng.csv by Liping Shi (734514)

“…The relative abundance of PBB, but not FPP, decreased after plant cultivation. There were significantly negative correlations between FPP and PBB, particularly the biocontrol subgroup (ρ = −0.56, p < 0.001). …”

Table3_Aconitate decarboxylase 1 mediates the acute airway inflammatory response to environmental exposures.docx by Aaron D. Schwab (18289974)

“…Aconitate decarboxylase 1 (Acod1) was one of the most upregulated genes following LPS (vs. saline) exposure of murine whole lungs with transcriptomic profiling of sorted lung monocyte/macrophage subpopulations also highlighting its significance. Given monocyte/macrophage activation can be tightly linked to metabolism, the objective of these studies was to determine the role of the immunometabolic regulator ACOD1 in environmental exposure-induced lung inflammation.…”