Quantitative Proteomics Unveils the Synergistic Effects of Combination Drugs on Cytoskeleton Composition and Autophagy-Mediated Cell Death in Neuroblastoma by Pei-Chen Yu (1860772)

Active DNA Demethylation Mediated by <i>OsGADD45a2</i> Regulates Growth, Development, and Blast (Magnaporthe oryzea) Resistance in Rice by Ganghua Zhou (9283406)

“…In <i>OsGADD45a2</i> overexpression lines, significant decreases in CG and CHG methylation levels were observed in protein-coding genes, leading to their upregulation. …”

Ultrafine Particulate Matter Exacerbates the Risk of Delayed Neural Differentiation: Modulation Role of METTL3-Mediated m⁶A Modification by Rui Wang (52434)

“…By employing <i>N</i>6-methyladenosine (m⁶A) methylated RNA immunoprecipitation sequencing and bioinformatics, we identified <i>Zic1</i> as a key target of PM_0.1-induced developmental disturbances. …”

Path diagram of the 2-factor CFA analysis. by Vincenza Tarantino (182506)

“…Interestingly, mediation analysis revealed that the S-Hab-Q score mediated the relationship between SPQ and AQ scores. …”

All DEGs in wild-type and <i>atb’’αβγδ</i> plants. by Hyuk Sung Yoon (20208672)

“…Transcriptome analysis showed a significant decrease in the expression of <i>CYP707A3</i>, a gene potentially targeted by VIP1 that regulates abscisic acid (ABA) catabolism, in the <i>atb’’αβγδ</i> mutant compared to wild type leaves. …”

Homer-derived motifs. by Hyuk Sung Yoon (20208672)

“…Transcriptome analysis showed a significant decrease in the expression of <i>CYP707A3</i>, a gene potentially targeted by VIP1 that regulates abscisic acid (ABA) catabolism, in the <i>atb’’αβγδ</i> mutant compared to wild type leaves. …”

All TPM values. by Hyuk Sung Yoon (20208672)

“…Transcriptome analysis showed a significant decrease in the expression of <i>CYP707A3</i>, a gene potentially targeted by VIP1 that regulates abscisic acid (ABA) catabolism, in the <i>atb’’αβγδ</i> mutant compared to wild type leaves. …”

Primer sequences. by Ceyan Kuang (8554557)

“…Microinjection of HL-IR double-stranded RNA (dsRNA) showed that reduced transcript levels led to significant decreases in the tick repellency rate from cinnamaldehyde and the EAG response of Haller’s organ. …”

SHAP dependence plots with interaction coloring. by Wentao Yang (205781)

“…</p><p>Conclusion</p><p>This first NHANES-based study demonstrates a significant negative correlation between eGDR and frailty, confirming DM’s partial mediating role. …”

Screening process diagram. by Wentao Yang (205781)

“…</p><p>Conclusion</p><p>This first NHANES-based study demonstrates a significant negative correlation between eGDR and frailty, confirming DM’s partial mediating role. …”

SHAP waterfall plot. by Wentao Yang (205781)

“…</p><p>Conclusion</p><p>This first NHANES-based study demonstrates a significant negative correlation between eGDR and frailty, confirming DM’s partial mediating role. …”

SHAP decision plot. by Wentao Yang (205781)

“…</p><p>Conclusion</p><p>This first NHANES-based study demonstrates a significant negative correlation between eGDR and frailty, confirming DM’s partial mediating role. …”

LASSO regression visualization plot. by Wentao Yang (205781)

“…</p><p>Conclusion</p><p>This first NHANES-based study demonstrates a significant negative correlation between eGDR and frailty, confirming DM’s partial mediating role. …”

SHAP dependence plots. by Wentao Yang (205781)

“…</p><p>Conclusion</p><p>This first NHANES-based study demonstrates a significant negative correlation between eGDR and frailty, confirming DM’s partial mediating role. …”

Tertile stratified subgroup analysis. by Wentao Yang (205781)

“…</p><p>Conclusion</p><p>This first NHANES-based study demonstrates a significant negative correlation between eGDR and frailty, confirming DM’s partial mediating role. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Functional Delivery Systems for Targeting Tumor Heterogeneity: Reversing Immunosuppression and Modulating Cancer-Immune Interplay by Di Han (618795)

“…After coincubation with edited CMCs, the proportions of CD8+CD69+ and CD8+CD44+ T cells significantly increase, while the proportion of CD4+Foxp3+ T_regs notably decreases, indicating the restoration of immune responses. …”

Data for Fig 6D. by Xiaohua Zhang (350570)

“…Further research showed that UL4 promoted the phosphorylation levels of SYK and JNK to enhance the ASC phosphorylation, which led to the increase of ASC oligomerization, thus promoting the activation of NLRP3 and AIM2 inflammasome and enhanced GSDMD-mediated pyroptosis. In <i>vivo</i> experiments further showed that PRV UL4 (¹³²DVAADAAAEAAAAE¹⁴⁵) mutated strain (PRV-UL4^mut) infection did not lead to a significant decrease in viral titers at 12 h. p. i, but it induced lower levels of IL-1β, IL-18, and GSDMD-NT, which led to an alleviated inflammatory infiltration and pathological damage in the lungs and brains, and a lower death rate compared with wild-type PRV strain infection. …”