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significantly weaker » significantly greater (Expand Search), significantly better (Expand Search), significantly related (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
weaker decrease » greater decrease (Expand Search), teer decrease (Expand Search), water decreases (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
significantly weaker » significantly greater (Expand Search), significantly better (Expand Search), significantly related (Expand Search)
significant decrease » significant increase (Expand Search), significantly increased (Expand Search)
weaker decrease » greater decrease (Expand Search), teer decrease (Expand Search), water decreases (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
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GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age.
Published 2021“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”
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Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver.
Published 2021“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”
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Significantly Enriched Pathways.
Published 2025“…Pathway analysis revealed a marked decrease in expression within certain key metabolic pathways (such as the one-carbon pool by folate) in the NAFLD group, while expression in DNA repair-related pathways (such as non-homologous end joining) was significantly increased. …”
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