DEG conditions and clusters. by Xiaoke Xu (3468623)

“…Our analysis revealed six distinct microglial clusters including homeostatic microglia, preactivated microglia, and activated microglia expressing high levels of inflammatory and disease-related molecules. …”

Infected cells in tissue and myeloid clusters. by Xiaoke Xu (3468623)

“…Our analysis revealed six distinct microglial clusters including homeostatic microglia, preactivated microglia, and activated microglia expressing high levels of inflammatory and disease-related molecules. …”

Comparative transcriptome analysis provides global insight into gene expression differences between two orchid cultivars by Yu Jiang (234328)

“…Biochemical analysis uncovered the contents of chlorophyll a, chlorophyll b, total chlorophyll and carotenoid were notably decreased in YL. …”

Data_Sheet_1_Molecular Signatures of Neuroinflammation Induced by αSynuclein Aggregates in Microglial Cells.xlsx by Souvarish Sarkar (8382513)

“…We validated progranulin (PGRN) as a lysosomal PD-associated protein that is downregulated by αSyn_Agg in microglia in-vivo and is expressed by microglia in post-mortem PD brain, congruent with our in vitro findings.…”

Myeloid cell comparison. by Xiaoke Xu (3468623)

“…Our analysis revealed six distinct microglial clusters including homeostatic microglia, preactivated microglia, and activated microglia expressing high levels of inflammatory and disease-related molecules. …”

<i>Gambiense</i> Human African Trypanosomiasis and Immunological Memory: Effect on Phenotypic Lymphocyte Profiles and Humoral Immunity by Veerle Lejon (116133)

“…<div><p>In mice, experimental infection with <i>Trypanosoma brucei</i> causes decreased bone marrow B-cell development, abolished splenic B-cell maturation and loss of antibody mediated protection including vaccine induced memory responses. …”

Data Sheet 1_Exhaustion of NK cells and interferon activation in anti-MDA5+ dermatomyositis are associated and determine the development of ILD.docx by Chenyi Shao (6444911)

“…Flow cytometry confirmed significantly decreased NK cell counts and increased apoptosis in the ILD group. …”

DataSheet_1_AURKA inhibitor-induced PD-L1 upregulation impairs antitumor immune responses.docx by Bi Meng (16970205)

“…</p>Results<p>We found that AURKA inhibitor MLN8237 promoted the expression of PD-L1 in a time- and concentration-dependent manner while exerted its antitumor effect. …”

DataSheet8_Guanxinkang Decoction Attenuates the Inflammation in Atherosclerosis by Regulating Efferocytosis and MAPKs Signaling Pathway in LDLR−/− Mice and RAW264.7 Cells.docx by Yifan Zhang (119570)

“…<p>Guanxinkang decoction (GXK), a traditional Chinese medicinal drug, is used to treat cardiovascular disease. …”

Pathway analysis. by Xiaoke Xu (3468623)

“…Our analysis revealed six distinct microglial clusters including homeostatic microglia, preactivated microglia, and activated microglia expressing high levels of inflammatory and disease-related molecules. …”

Seq and cell summary. by Xiaoke Xu (3468623)

“…Our analysis revealed six distinct microglial clusters including homeostatic microglia, preactivated microglia, and activated microglia expressing high levels of inflammatory and disease-related molecules. …”

Table_1_The impact of Bacillus subtilis DSM32315 and L-Threonine supplementation on the amino acid composition of eggs and early post-hatch performance of ducklings.doc by Mahmoud Mostafa Azzam (16868625)

“…In addition, L-Thr supplementation resulted in a tendency for decreased feed conversion ratio without affecting egg quality. …”

Table_2_Cellular Mechanisms Underlying B Cell Abnormalities in Patients With Gain-of-Function Mutations in the PIK3CD Gene.docx by Wenjie Wang (413433)

“…</p>Conclusions<p>The present study suggests additional mechanistic insight into B cell pathology of APDS: (1) decreased peripheral B cell numbers may be due to the increased death of naïve B cells; (2) larger B cell sizes and expanded DNB population suggest enhanced activation and differentiation of naïve B cells into DNB cells; (3) the impaired CSR yet normal PB differentiation can predominantly generate IgM-secreting cells, resulting in elevated IgM levels.…”

Data_Sheet_1_Multiple treatment interruptions and protecting HIV-specific CD4 T cells enable durable CD8 T cell response and viral control.PDF by Anshika Jain (8037536)

“…Four patients participated in a second ATI. During the second ATI, the Gag-specific CD8 T cells were either maintained or rose in response to viral rebound and the peak viremia was substantially decreased. …”

Alternative Approach for an Anomalous Pulmonary Venous Connection to the Superior Vena Cava by Roman Sekelyk (17840822)

“…<p dir="ltr">A mildly symptomatic seven-year-old male patient presented with a high partial anomalous pulmonary venous connection of the right upper and middle veins into the superior vena cava high above the right pulmonary artery with a secundum atrial septal defect. …”

5′pppRNA activates innate immunity and protects mice from lethal influenza infection <i>in vivo</i>. by Marie-Line Goulet (407117)

“…Error bars represent SEM from six different animals. ND: not detected. (<b>D</b>) Repetitive administration of 5′pppRNA on the indicated days further decreases lung viral titers following infection with 500 PFU of influenza, as determined by plaque assay on Day 3 post-infection. …”

Table_3_Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential.DOCX by Zhengxi Wei (7846514)

“…However, there has not yet been a large-scale comparison of the effects of topical-use compounds in different cellular skin models. …”

Image_1_Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential.JPEG by Zhengxi Wei (7846514)

“…However, there has not yet been a large-scale comparison of the effects of topical-use compounds in different cellular skin models. …”

image1_Polyporus Umbellatus Protects Against Renal Fibrosis by Regulating Intrarenal Fatty Acyl Metabolites.pdf by Yan-Ni Wang (1930960)

“…</p><p>Results: Compared with control group, decreased creatinine clearance rate indicated declining kidney function in CRF group. …”

Table1_Systematic review and meta-analysis of Chinese herbal formula Tongxie Yaofang for diarrhea-predominant irritable bowel syndrome: Evidence for clinical practice and future tr... by Shi-Bing Liang (10200806)

“…Ancient classical Chinese medical texts have recognized Tongxie Yaofang (TXYF) as a therapy for diarrhea which is widely used in clinical practice. …”